Results 61 to 70 of about 2,525,619 (266)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Journal of Modern ScienceObjectives The aim of the work is to discuss selected issues related to administrative-legal activities concerning the naming of streets and squares in the practice of functioning of basic units of local government.
Krzysztof Henryk Lewandowski
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
The "Game about Squares" is NP-hard [PDF]
, 2014 In the "Game about Squares" the task is to push unit squares on an integer lattice onto corresponding dots. A square can only be moved into one given direction. When a square is pushed onto a lattice point with an arrow the direction of the square adopts
Maßberg, Jens
core
The Pythagoras number and the $u$-invariant of Laurent series fields in several variables
, 2015 We show that every sum of squares in the three-variable Laurent series field $\mathbb{R}((x,y,z))$ is a sum of 4 squares, as was conjectured in a paper of Choi, Dai, Lam and Reznick in the 1980's.
Hu, Yong
core +1 more source
Atmosphere, 2021 China was the first country to undergo large-scale lockdowns in response to the pandemic in early 2020 and a progressive return to normalization after April 2020.
Trissevgeni Stavrakou +19 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Distinct Squares in Circular Words
, 2017 A circular word, or a necklace, is an equivalence class under conjugation of a word. A fundamental question concerning regularities in standard words is bounding the number of distinct squares in a word of length $n$.
Amit, Mika, Gawrychowski, Paweł
core +1 more source