Results 71 to 80 of about 878,007 (304)

Role of the adaptor protein PDZK1 in controlling the HDL receptor SR-BI [PDF]

Current Opinion in Lipidology, 2009
Regulation of lipoprotein receptor activity influences lipoprotein metabolism, related physiology and pathophysiology. Adaptor proteins that bind to the LDL or HDL receptors apparently link these receptors to cellular components essential for their normal functioning. Here, we focus on the influence of PDZK1 on the HDL receptor scavenger receptor class
Monty Krieger, Olivier Kocher
openaire   +3 more sources

Traversing the Periodic Table through Phase‐Separating Nanoreactors

Advanced Materials, EarlyView.
Centimeter‐scale arrays of single nanoparticles, generated through either Dip Pen Nanolithography or Polymer Pen Lithography, allow for the discovery of novel nanomaterials at an unprecedented scale. The development of phase‐separating hydrophobic nanoreactors bypasses element‐specific chemistry limitations, enabling the synthesis of polyelemental ...
Carolin B. Wahl, Jordan H. Swisher, Peter T. Smith, Vinayak P. Dravid, Chad A. Mirkin   +4 more
wiley   +1 more source

Identification of novel neutralizing determinants for protection against HCV

Hepatology, EarlyView., 2022
Identification of novel neutralizing determinants for protection against hepatitis C virus. Abstract Background and Aims HCV evasion of neutralizing antibodies (nAb) results in viral persistence and poses challenges to the development of an urgently needed vaccine.
Garazi P. Alzua, Anne F. Pihl, Anna Offersgaard, Rodrigo Velázquez‐Moctezuma, Carlos R. Duarte Hernandez, Elias H. Augestad, Ulrik Fahnøe, Christian K. Mathiesen, Henrik Krarup, Mansun Law, Jannick Prentoe, Jens Bukh, Judith M. Gottwein   +12 more
wiley   +1 more source

Differentiation-dependent expression and localization of the class B type I scavenger receptor in intestine

Journal of Lipid Research, 2001
The current study used the human Caco-2 cell line and mouse intestine to explore the topology of expression of the class B type I scavenger receptor (SR-BI) in intestinal cells.
Sheng F. Cai, R. Jason Kirby, Philip N. Howles, David Y. Hui   +3 more
doaj  

Procollagen C-endopeptidase Enhancer Protein 2 (PCPE2) Reduces Atherosclerosis in Mice by Enhancing Scavenger Receptor Class B1 (SR-BI)-mediated High-density Lipoprotein (HDL)-Cholesteryl Ester Uptake*

Journal of Biological Chemistry, 2015
Background: Extracellular matrix protein PCPE2 is linked to alterations in HDL size and concentration. Results: PCPE2 protects against diet-induced atherosclerosis by promoting HDL catabolism, reverse cholesterol transport, and SR-BI-mediated uptake of ...
R. D. Pollard, C. Blesso, Manal Zabalawi, Brian E. Fulp, Mark Gerelus, Xuewei Zhu, Erica W. Lyons, N. Nuradin, O. Francone, Xiang-An Li, D. Sahoo, Michael J. Thomas, M. Sorci-Thomas   +12 more
semanticscholar   +1 more source

Role of SR-BI in atherosclerosis, malignancies, and infectious diseases [PDF]

Infection International, 2018
Abstract Scavenger receptor class B type I (SR-BI) is a high-affinity receptor for high-density lipoprotein (HDL). The primary role of this receptor is the selective uptake of HDLs in the liver through reverse cholesterol transport. SR-BI interacts with HDL to regulate lipid metabolism and affects various vascular cell functions involved in ...
openaire   +1 more source

Leveraging Grain Boundary Effects for Nanostructured Electrode Layers in Symmetric Solid Oxide Fuel Cells

Advanced Materials Interfaces, EarlyView.
Nanocrystalline thin‐films of lanthanum chromite exhibit extraordinary properties of fast oxygen kinetics. These properties are due to the peculiar chemistry of grain boundaries and can be harnessed for fabricating symmetric electrochemical devices with self‐healing properties. Abstract While grain boundary engineering is attracting great interest as a
Federico Baiutti, Francesco Chiabrera, Marlene Anzengruber, Kosova Kreka, Juande Sirvent, Lluis Yedra, Fjorelo Buzi, Macej Oskar Liedke, Andrea Cavallaro, Albert Carmona Zuazo, Sonia Estradé, Maik Butterling, Eric Hirschmann, Andreas Wagner, Ainara Aguadero, Francisca Peiró, Albert Tarancon   +16 more
wiley   +1 more source

17β-Estradiol promotes the up-regulation of SR-BII in HepG2 cells and in rat livers

Journal of Lipid Research, 2001
The scavenger receptor class B type I (SR-BI) binds to HDL and mediates the selective uptake of cholesterol esters from HDL to cells. SR-BII is an alternatively spliced product of the SR-BI gene that only differs in the C-terminal cytoplasmic domain ...
Gregory A. Graf, Kathy L. Roswell, Eric J. Smart   +2 more
doaj  

Rutaecarpine suppresses atherosclerosis in ApoE−/− mice through upregulating ABCA1 and SR-BI within RCT[S]

Journal of Lipid Research, 2014
ABCA1 and scavenger receptor class B type I (SR-BI)/CD36 and lysosomal integral membrane protein II analogous 1 (CLA-1) are the key transporter and receptor in reverse cholesterol transport (RCT).
Yanni Xu, Qi Liu, Yang Xu, Chang Liu, Xiao Wang, Xiaobo He, N. Zhu, Jikai Liu, Ye-xiang Wu, Yongzhen Li, Ni Li, T. Feng, F. Lai, Murui Zhang, B. Hong, Jiandong Jiang, S. Si   +16 more
semanticscholar   +1 more source

PCPE2 and SR-BI Partner to Impact Accumulation of Fat in Mice [PDF]

, 2018
ABSTRACTLDL receptor knockout mice (LDLr-/-) were crossed with PCPE2 knockout mice to obtainLdlr-/-,Pcpe2-/-mice. The rationale of these studies was to examine the effects of an extracellular matrix protein, PCPE2, on fat storage in a dyslipidemic mouse model.
Xu, Hao, Kaul, Sushma, Kallinger, Rachel, Thomas, Michael J., Schill, Rebecca L., Sahoo, Daisy, Sorci-Thomas, Mary G.   +6 more
openaire   +2 more sources