Results 51 to 60 of about 1,272,764 (261)

Challenges in using cultured primary rodent hepatocytes or cell lines to study hepatic HDL receptor SR-BI regulation by its cytoplasmic adaptor PDZK1. [PDF]

PLoS ONE, 2013
PDZK1 is a four PDZ-domain containing cytoplasmic protein that binds to a variety of membrane proteins via their C-termini and can influence the abundance, localization and/or function of its target proteins.
Kosuke Tsukamoto, Lorenna Buck, Walker Inman, Linda Griffith, Olivier Kocher, Monty Krieger   +5 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Intestinal SR-BI does not impact cholesterol absorption or transintestinal cholesterol efflux in mice

Journal of Lipid Research, 2013
Reverse cholesterol transport (RCT) can proceed through the classic hepatobiliary route or through the nonbiliary transintestinal cholesterol efflux (TICE) pathway.
Kanwardeep S. Bura, Caleb Lord, Stephanie Marshall, Allison McDaniel, Gwyn Thomas, Manya Warrier, Jun Zhang, Matthew A. Davis, Janet K. Sawyer, Ramesh Shah, Martha D. Wilson, Arne Dikkers, Uwe J.F. Tietge, Xavier Collet, Lawrence L. Rudel, Ryan E. Temel, J.Mark Brown   +16 more
doaj   +1 more source

Developmental abnormalities in mouse embryos lacking the HDL receptor SR-BI [PDF]

Human Molecular Genetics, 2012
The srbi gene encodes a lipoprotein receptor with high affinity for high density lipoprotein that is mainly expressed in the liver and in steroidogenic tissues. Disruption of this gene in mice and mutations in humans lead to alterations in lipoprotein metabolism and/or fertility. During murine development, scavenger receptor class B member I (SR-BI) is
Santander, Nicolás Guillermo, Contreras Duarte, Susana de las Mercedes, Awad, María Fernanda, Lizama, Carlos, Passalacqua, Isabella, Rigotti Rivera, Attilio, Busso, Dolores   +6 more
openaire   +6 more sources

SR-BI attenuates monocyte recruitment.

, 2013
A. ICAM-1 binding, B. VCAM-1 binding, by monocytes from SR-BI+/+apoE-hypomorphic (blue) or SR-BI−/−apoE-hypomorphic mice (red) as determined by flow cytometry. Representative histograms of 4 replicates are shown.
Mark T. Fuller (445277), Pei Yu (203358), Suleiman A. Igdoura (445280), Bernardo L. Trigatti (445281), Elizabeth J. White (445279), Dina Aboutouk (445276), Ying Pei (445275), Xing Chen (140292), Omid Dadoo (445278)   +8 more
core   +1 more source

Extending Service Beyond Active Duty: Generalizability of Rheumatoid Arthritis Research Conducted Among U.S. Veterans

Arthritis Care &Research, Accepted Article.
Biomedical research involving United States Veterans continues to advance healthcare beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where Veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both ...
Austin M. Wheeler, Joshua F. Baker, Jennifer L. Barton, Maria I. Danila, Tate M. Johnson, Kamini Kuchinad, Kaleb Michaud, Amir A. Razmjou, J. Steuart Richards, Namrata Singh, Isaac D. Smith, Katherine D. Wysham, Grant W. Cannon, Bryant R. England, Amy Joseph, Deana Lazaro, Katherine P. Liao, Courtney Loecker, Andreas Reimold, Beth I. Wallace, Ted R. Mikuls   +20 more
wiley   +1 more source

Control of Polarization and Polar Helicity in BiFeO3 by Epitaxial Strain and Interfacial Chemistry

Advanced Functional Materials, EarlyView.
In BiFeO3 thin films, the interplay of interfacial chemistry, electrostatics, and epitaxial strain is engineered to stabilize homohelicity in polarization textures at the domain scale. The synergistic use of a Bi2O2‐terminated Aurivillius buffer layer and a highly anisotropic compressive epitaxial strain offers new routes to control the polar‐texture ...
Elzbieta Gradauskaite, Lilia Huynh, Natascha Gray, Quintin N. Meier, Marta D. Rossell, Morgan Trassin   +5 more
wiley   +1 more source

Scavenger receptor BI facilitates hepatic very low density lipoprotein production in mice

Journal of Lipid Research, 2010
Scavenger receptor BI (SR-BI) is a selective uptake receptor for HDL cholesterol but is also involved in the catabolism of apolipoprotein (apo)B-containing lipoproteins. However, plasma levels of apoB-containing lipoproteins increase following hepatic SR-
Harmen Wiersma, Niels Nijstad, Thomas Gautier, Jahangir Iqbal, Folkert Kuipers, M. Mahmood Hussain, Uwe J.F. Tietge   +6 more
doaj   +1 more source

Valuing Banks: Case Study of Sparebank 1 SR-Bank [PDF]

, 2018
Masteroppgave(MSc) in Master of Science in Business, Finance - Handelshøyskolen BI, 2018The purpose of this thesis is to identify the value of Sparebank 1 SR-Bank (SRBANK) as of 31.12.2017.
Indergaard, Einar Lie, Thiis-Evensen, Asbjørn   +1 more
core  

Omnipolar Magnetic Field Detection by Superlattice‐Based Hall Sensor

Advanced Functional Materials, EarlyView.
Magnetic‐field‐induced electronic switching is demonstrated in unit‐cell‐engineered La0.7Sr0.3MnO3–BiFeO3 superlattices. Distinct substrate terminations modify magnetic and transport properties. Hall resistance measurements show omnipolar, hysteretic anomalous Hall switching above the Curie temperature, arising from Fe─Mn interfacial exchange, enabling
Mark Huijben, Nicolas Gauquelin, Arno Annys, Zhaoliang Liao, Jo Verbeeck, Guus Rijnders, Gertjan Koster   +6 more
wiley   +1 more source