Results 71 to 80 of about 895,142 (270)

Regulation of adrenal scavenger receptor-BI expression by ACTH and cellular cholesterol pools

Journal of Lipid Research, 1999
Scavenger receptor BI (SR-BI) mediates selective uptake of high density lipoprotein (HDL) cholesteryl ester in the liver and adrenal gland. Adrenal SR-BI is increased both in adrenocorticotropic hormone (ACTH)-treated mice and also in apolipoprotein A-I ...
Yu Sun, Nan Wang, Alan R. Tall
doaj   +1 more source

Multi‐Channel Electrically Tunable Varifocal Metalens With Compact Multilayer Polarization‐Dependent Metasurfaces and Liquid Crystals

Advanced Science, EarlyView.
A compact eight‐channel electrically tunable varifocal metalens with three single‐layer polarization‐multiplexed bi‐focal metalens and three LC cells. The total thickness of the device is ∼6 mm, while the focal lengths can be switched among eight values (3.6, 4.2, 4.5, 4.9, 6.2, 6.9, 8.4, and 9.6 mm). ABSTRACT As an essential module of optical systems,
Zhiyao Ma, Yize Liu, Zhe Li, Tian Tian, Yuxuan Liao, Xue Feng, Yongzhuo Li, Kaiyu Cui, Fang Liu, Hao Sun, Wei Zhang, Yidong Huang   +11 more
wiley   +1 more source

Scavenger receptor class B type I is solely responsible for the selective uptake of cholesteryl esters from HDL by the liver and the adrenals in mice

Journal of Lipid Research, 2004
Scavenger receptor class B type I (SR-BI) has been identified as a functional HDL binding protein that can mediate the selective uptake of cholesteryl ester (CE) from HDL.
Ruud Out, Menno Hoekstra, John A.A. Spijkers, Johan K. Kruijt, Miranda van Eck, Ingrid S.T. Bos, Jaap Twisk, Theo J.C. Van Berkel   +7 more
doaj   +1 more source

Restoration of SR-BI expression in BM derived cells attenuates diet induced increases in heart size and cardiac fibrosis in SR-BI-null/apoE-hypomorphic mice.

, 2013
A. Ratios of heart weight to body weight (HW:BW) are plotted for SR-BI−/− → SR-BI−/− mice (circles) and SR-BI+/+ → SR-BI−/− mice (diamonds) fed the HFCC diet for 4 weeks.
Mark T. Fuller (445277), Pei Yu (203358), Suleiman A. Igdoura (445280), Bernardo L. Trigatti (445281), Elizabeth J. White (445279), Dina Aboutouk (445276), Ying Pei (445275), Xing Chen (140292), Omid Dadoo (445278)   +8 more
core   +1 more source

Temperature‐Driven Emission Redistribution of Yb2+ in SrB4O7 Enables Highly Sensitive Optical Thermometry Supported by Multiple Linear Regression

Advanced Science, EarlyView.
A novel optical thermometer exploits the rare UV emission of Yb2+ ions in a SrB4O7 host, enabling highly sensitive, non‐contact temperature measurements from 80 to 420 K. The applied multiple linear regression (MLR) analysis results in a multiple increase in the resulting temperature sensitivity.
Fang Zhao, Teng Zheng, Przemysław Woźny, Miguel A. Hernández‐Rodríguez, Shiqing Xu, Inocencio R. Martín, Marcin Runowski   +6 more
wiley   +1 more source

Distinct mechanisms for OxLDL uptake and cellular trafficking by class B scavenger receptors CD36 and SR-BI

Journal of Lipid Research, 2007
Modified forms of LDL, including oxidized low density lipoprotein (OxLDL), contribute to macrophage lipid accumulation in the vessel wall. Despite the pathophysiological importance of uptake pathways for OxLDL, the molecular details of OxLDL endocytosis ...
Bing Sun, Boris B. Boyanovsky, Margery A. Connelly, Preetha Shridas, Deneys R. van der Westhuyzen, Nancy R. Webb   +5 more
doaj   +1 more source

The role of the high-density lipoprotein receptor SR-BI in cholesterol metabolism

Current Opinion in Lipidology, 2000
The HDL receptor scavenger receptor class B type I (SR-BI), which mediates selective HDL cholesterol uptake, plays a role in murine HDL metabolism, reverse cholesterol transport and whole-body cholesterol homeostasis. SR-BI is found in the liver, where its expression is regulated by estrogen, dietary cholesterol and fat, and controls murine plasma HDL ...
Trigatti, B, Rigotti, A, Krieger, M
openaire   +4 more sources

Quantitative analysis of SR-BI-dependent HDL retroendocytosis in hepatocytes and fibroblasts [PDF]

Journal of Lipid Research, 2006
Previous studies have suggested that HDL retroendocytosis may play a role in scavenger receptor class B type I (SR-BI)-dependent selective lipid uptake in a cell-specific manner. To investigate this possibility, we developed methods to quantitatively measure HDL uptake and resecretion in fibroblast (COS-7) and hepatocyte (HepG2) cells expressing ...
Bing Sun, Erik R.M. Eckhardt, Shoba Shetty, Deneys R. van der Westhuyzen, Nancy R. Webb   +4 more
openaire   +3 more sources

Asymmetric Electrostrain/Electrobending in Piezoelectric Ceramics: Role of Defect Dipoles or Oxygen Vacancies

Advanced Science, EarlyView.
Defect‐configurational origins of the asymmetric apparent electrostrain are revealed in different piezoelectric ceramics via atomic‐scale visualization of defect configurations. Migration of oxygen vacancies leads to the electrobending effect in N2‐sintered BaTiO3, while defect dipoles in Ba0.99TiO2.99 generate true asymmetric electrostrain without ...
Jie Wang, Geng Huangfu, Hongjie Zhang, Tiannan Yang, Zhenhua Ma, Jingsheng Chen, Yun Liu, Yiping Guo   +7 more
wiley   +1 more source

BCMA‐Engineered Dendritic Cell‐Derived Exosomes as Bi‐Functional Therapeutics Orchestrating Cytokine Sequestration and Immune Activation for Multiple Myeloma

Advanced Science, EarlyView.
A dual‐function cell‐free therapeutic based on DC2.4 cell‐derived exosomes engineered to display BCMA. (Left) Soluble Ligand Sequestration (Decoy Function): DB Exo act as molecular decoys that predominantly sequester soluble APRIL with partial BAFF attenuation, effectively disrupting the NF‐κB survival signaling axis and suppressing myeloma cell ...
Yuqing Zeng, Chao He, Zhibin He, Hongbo Chen, Fang Cheng, Yongjiang Zheng   +5 more
wiley   +1 more source