Background Plasmodium falciparum STEVOR proteins, encoded by the multicopy stevor gene family have no known biological functions. Their expression and unique locations in different parasite life cycle stages evoke multiple functionalities.
Petter Michaela +5 more
doaj +4 more sources
CD36 Signal Transduction in Metabolic Diseases: Novel Insights and Therapeutic Targeting
The cluster of differentiation 36 (CD36) is a scavenger receptor present on various types of cells and has multiple biological functions that may be important in inflammation and in the pathogenesis of metabolic diseases, including diabetes.
Udayakumar Karunakaran +3 more
doaj +3 more sources
Identification of differentially expressed genes associated with tracheal injury recovery in a rabbit model of septic shock [PDF]
Background Sepsis is a syndrome caused by the host’s inflammatory response to an infection with an unknown mechanism. This study aimed to identify differentially expressed genes (DEGs) potentially involved in the development and recovery of tracheal ...
Pei Zhang +8 more
doaj +2 more sources
PPARα modulation of macrophage polarization and inflammatory signaling in mimic periodontitis [PDF]
Objective This study investigates the role of peroxisome proliferator-activated receptor alpha (PPARα) in regulating macrophage polarization and inflammatory signaling under stimulation by periodontal pathogens.
HU Arthur, Yvette Y CHEN
doaj +2 more sources
Plasma CD36 and Incident Diabetes: A Case-Cohort Study in Danish Men and Women [PDF]
BackgroundMembrane CD36 is a fatty acid transporter implicated in the pathogenesis of metabolic disease. We aimed to evaluate the association between plasma CD36 levels and diabetes risk and to examine if the association was independent of adiposity ...
Yeli Wang +8 more
doaj +1 more source
The Role of CD36 in Type 2 Diabetes Mellitus: β-Cell Dysfunction and Beyond [PDF]
Impaired β-cell function is the key pathophysiology of type 2 diabetes mellitus, and chronic exposure of nutrient excess could lead to this tragedy.
Jun Sung Moon +4 more
doaj +1 more source
Objective To search compatible and suitable platelets for platelet transfusion refractoriness (PTR) patient caused by compound antibodies against HLA and CD36.
Jing DENG +10 more
doaj +1 more source
Analysis and prospect of platelet compatible transfusion
Platelet compatible transfusion can effectively solve the immune mediated platelet transfusion refractoriness (PTR), save platelet resources and improve blood safety.
Faming ZHU, Wei MAO, Zhixin ZHANG
doaj +1 more source
Macrophages are innate immune cells that internalize and present exogenous antigens to T cells via MHC class II proteins. They operate at sites of infection in a highly inflammatory environment, generated in part by reactive oxygen species, in particular
Agnes Ulfig +5 more
doaj +1 more source
Neonatal Intracranial Hemorrhage with a Dramatic Outcome Due to Maternal Anti CD36 Antibodies
Fetal/neonatal allo-immune thrombocytopenia (FNAIT) results from maternal immunization against fetal platelet-specific antigens (HPA) inherited from the father. Most cases involve HPA located on glycoproteins (GP) IbIX, IaIIa and IIbIIIa.
Gérald Bertrand +5 more
doaj +1 more source

