Annals of Laboratory Medicine, 2022 Antibodies against human CD36 are responsible for several immune-mediated disorders. The detection of anti-CD36 antibodies using the standard monoclonal antibody (mAb) immobilization of platelet antigens (MAIPA) assay is hampered by a high frequency of false-negative results, most likely due to competitive inhibition of the mAb used as the capture ...
Xiuzhang Xu +11 more
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Oxidation by neutrophils-derived HOCl increases immunogenicity of proteins by converting them into ligands of several endocytic receptors involved in antigen uptake by dendritic cells and macrophages. [PDF]
PLoS ONE, 2015 The initiation of adaptive immune responses to protein antigens has to be preceded by their uptake by antigen presenting cells and intracellular proteolytic processing.
Rafał Biedroń +3 more
doaj +1 more source
Infectivity of Plasmodium falciparum in malaria-naive individuals is related to knob expression and cytoadherence of the parasite [PDF]
, 2016 Plasmodium falciparum is the most virulent human malaria parasite because of its ability to cytoadhere in the microvasculature. Nonhuman primate studies demonstrated relationships among knob expression, cytoadherence, and infectivity.
Beeson, James G. +20 more
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Decrease of Very Late Activation Antigen-4 and CD36 on Reticulocytes in Sickle Cell Patients Treated With Hydroxyurea [PDF]
Blood, 1997 Abstract Sickle cell disease (SCD) is characterized by repeated vaso-occlusive events, which result in substantial morbidity. Abnormal adhesion of sickle red blood cells (RBC) to the vascular endothelium is postulated to play a role in the pathogenesis of vaso-occlusion.
L A, Styles +6 more
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Malaria vaccines 1985-2005: a full circle?
, 2005 Few who were actively engaged in malaria vaccine research 20 years ago (including myself) would have imagined that, in 2005, there would still be a prediction of a 10-20-year horizon before vaccines become part of malaria-control strategies.
Targett, Geoffrey A
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src‐related protein tyrosine kinases are physically associated with the surface antigen CD36 in human dermal microvascular endothelial cells [PDF]
FEBS Letters, 1994 src‐related cytoplasmic PTKs are physically and functionally associated with cell surface receptors and are involved in signal transduction. In this paper we report the identification of src‐related proteins p59 fyn , pp60c‐scr and p62 yes in human microvascular endothelial cells cultured from normal human skin and their physical association with ...
Bull, Helen A. +2 more
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Revista Brasileira de Hematologia e Hemoterapia, 2012 Chronic myelomonocytic leukemia is a clonal stem cell disorder that is characterized mainly by absolute peripheral monocytosis. This disease can present myeloproliferative and myelodysplastic characteristics.
Iris Mattos Santos +2 more
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Capacity strengthening in malaria research: the Gates Malaria Partnership.
, 2006 The Gates Malaria Partnership (GMP) includes five African and four European partner institutions. Its research programme has five priority areas involving an extensive range of field-based studies.
Bhasin, Amit +4 more
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Cytoadhesion to gC1qR through Plasmodium falciparum Erythrocyte Membrane Protein 1 in Severe Malaria [PDF]
, 2016 Cytoadhesion of Plasmodium falciparum infected erythrocytes to gC1qR has been associated with severe malaria, but the parasite ligand involved is currently unknown.
Aide, Pedro Carlos Paulino +20 more
core +3 more sources
, 2001 Combination therapy that includes artemisinin derivatives cures most falciparum malaria infections. Lowering transmission by reducing gametocyte infectivity would be an additional benefit.
Targett, G +10 more
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