Results 41 to 50 of about 9,756 (185)

Alpha (v) integrins license regulatory T cells to apoptotic cells and self-associated antigens

, 2010
Defects in apoptotic cell clearance are thought to contribute to autoimmunity by failure to induce tolerance, coupled with accumulation of immunogenic material.
Paidassi, Helena, Lacy-Hulbert, Adam, Helena Païdassi, Adam Lacy-Hulbert, Mridu Acharya, Acharya, Mridu   +5 more
core   +1 more source

Improvement of Anti-CD36 Antibody Detection via Monoclonal Antibody Immobilization of Platelet Antigens Assay by Using Selected Monoclonal Antibodies

Annals of Laboratory Medicine, 2022
Antibodies against human CD36 are responsible for several immune-mediated disorders. The detection of anti-CD36 antibodies using the standard monoclonal antibody (mAb) immobilization of platelet antigens (MAIPA) assay is hampered by a high frequency of false-negative results, most likely due to competitive inhibition of the mAb used as the capture ...
Xiuzhang Xu, Dawei Chen, Xin Ye, Wenjie Xia, Yuan Shao, Jing Deng, Yangkai Chen, Haoqiang Ding, Jing Liu, Yaori Xu, Sentot Santoso, Yongshui Fu   +11 more
openaire   +2 more sources

CD36 deficiency in mice impairs lipoprotein lipase-mediated triglyceride clearance

, 2005
CD36 is involved in high-affinity peripheral FFA uptake. CD36-deficient (cd36-/-) mice exhibit increased plasma FFA and triglyceride (TG) levels. The aim of the present study was to elucidate the cause of the increased plasma TG levels in cd36-/- mice ...
Romijn, Johannes A., Romijn, J A, Havekes, Louis M., oer, M.A.M. den, Febbraio, M, Havekes, L.M., Febbraio, Maria, Voshol, Peter J., Rensen, Patrick C. N., Febbraio, M., Goudriaan, J R, Kuipers, F., Goudriaan, J.R., Goudriaan, Jeltje R., Voshol, P.J., Voshol, P J, Kuipers, F, Romijn, J.A., Rensen, P.C.N., Havekes, L M, Kuipers, F; id_orcid, Kuipers, Folkert, Rensen, P C N, den Boer, Marion A. M., den Boer, M A M   +24 more
core   +1 more source

Parasite infectivity and immunity to Plasmodium falciparum gametocytes in Gambian children.

, 2004
Immunity to the sexual stages of Plasmodium falciparum can be induced during natural infections. Characterization of this immunity may facilitate the design of a transmission-blocking vaccine (TBV).
Bousema, T., Greenwood, BM, Targett, GAT, Sauerwein, R, Teelen, K.A.E.M., Sauerwein, R.W., Drakeley, CJ, Targett, G.A.T., Bousema, JT, Eling, W.M.C., Greenwood, B.M., Eling, W, Drakeley, C., Teelen, K   +13 more
core   +1 more source

Sickle cell protection from malaria: a review

Hematology Reports, 2011
A linkage between presence of Sickle Haemoglobin (HbS) and protection from malaria infection and clinical manifestations in certain areas was suspected from early observations and progressively elucidated by more recent studies.
Sandro Eridani
doaj   +1 more source

Identification of an immunodominant functional domain on human CD36 antigen using human-mouse chimaeric proteins and homologue-replacement mutagenesis [PDF]

Biochemical Journal, 1995
The human CD36 antigen is a multifunctional membrane glycoprotein that acts as a receptor for thrombospondin, malaria-infected erythrocytes and oxidized low-density lipoprotein, as well as being implicated in the recognition of apoptotic neutrophils by macrophages.
L, Daviet, R, Buckland, M D, Puente Navazo, J L, McGregor   +3 more
openaire   +2 more sources

Plasmodium falciparum variant STEVOR antigens are expressed in merozoites and possibly associated with erythrocyte invasion

Malaria Journal, 2008
Background Plasmodium falciparum STEVOR proteins, encoded by the multicopy stevor gene family have no known biological functions. Their expression and unique locations in different parasite life cycle stages evoke multiple functionalities.
Petter Michaela, Schreiber Nadine, Bonow Insa, Khattab Ayman, Schmetz Christel, Klinkert Mo-Quen   +5 more
doaj   +1 more source

Differential regulation of CD36 expression in antigen-presenting cells: Oct-2 dependence in B lymphocytes but not dendritic cells or macrophages [PDF]

International Immunology, 2002
In mice, three antigen-presenting cell types [B lymphocytes, macrophages and dendritic cells (DC)] express the scavenger receptor CD36. This molecule has been implicated in many important functions, including DC maturation and antigen presentation. In murine B cells, the CD36 gene requires the Oct-2 transcription factor for its expression.
Lynn, Corcoran, David, Vremec, Maria, Febbraio, Tracey, Baldwin, Emanuela, Handman   +4 more
openaire   +2 more sources

Malaria vaccines 1985-2005: a full circle? [PDF]

, 2005
Few who were actively engaged in malaria vaccine research 20 years ago (including myself) would have imagined that, in 2005, there would still be a prediction of a 10-20-year horizon before vaccines become part of malaria-control strategies.
Targett, Geoffrey A
core   +1 more source

Influence of the Clinical Status on Stress Reticulocytes, CD 36 and CD 49d of SSFA2 Homozygous Sickle Cell Patients Followed in Abidjan

Advances in Hematology, 2014
Background and Objectives. Interactions between sickle cells involving CD 49d, CD36, and the vascular endothelium may initiate vasoocclusion leading to acute painful episodes and multiple organ failure. Materials and Methods.
Duni Sawadogo, Aïssata Tolo-Dilkébié, Mahawa Sangaré, Nelly Aguéhoundé, Hermance Kassi, Toussaint Latte   +5 more
doaj   +1 more source