Results 61 to 70 of about 9,756 (185)

Induction of monocyte differentiation and foam cell formation in vitro by 7-ketocholesterol

Journal of Lipid Research, 2002
Oxidized LDL (OxLDL) is composed of many potentially proatherogenic molecules, including oxysterols. Of the oxysterols, 7-ketocholesterol (7-KC) is found in relatively large abundance in OxLDL, as well as in atherosclerotic plaque and foam cells in vivo.
John M. Hayden, Libuse Brachova, Karen Higgins, Lewis Obermiller, Alex Sevanian, Srikrishna Khandrika, Peter D. Reaven   +6 more
doaj   +1 more source

Inhibition of phosphatidylserine recognition heightens the immunogenicity of irradiated lymphoma cells in vivo

, 2004
Strategies to enhance the immunogenicity of tumors are urgently needed. Although vaccination with irradiated dying lymphoma cells recruits a tumor-specific immune response, its efficiency as immunogen is poor.
Zimmermann, VS, Voll, Reinhard E., Turnay, Javier, Manfredi, Angelo A., Turnay, J, Dumitriu, IE, Voll, RE, Zimmermann, Valérie S, Angelo A. Manfredi, Bertling, Wolf, Rovere-Querini, P, Kalden, JR, Udo S. Gaipl, Herrmann, M, Attilio Bondanza, Gaipl, Udo S, Wolf Bertling, Bertling, W, Patrizia Rovere-Querini, Ingrid E. Dumitriu, Bondanza, Attilio, Stach, Christian M., Pöschl, E, Stach, Christian M, Gaipl, US, Javier Turnay, Herrmann, Martin, Martin Herrmann, Dumitriu, Ingrid E., Rovere-Querini, Patrizia, Christian M. Stach, Manfredi, Angelo A, Kalden, Joachim R, Valérie S. Zimmermann, Pöschl, Ernst, Stach, CM, Dumitriu, Ingrid E; id_orcid, Gaipl, Udo S., Joachim R. Kalden, Bondanza, A, Zimmermann, Valérie S., Voll, Reinhard E, Kalden, Joachim R., Reinhard E. Voll, Manfredi, AA, Ernst Pöschl   +45 more
core   +1 more source

"Plasmodium falciparum var" Gene Expression Dynamics and its Relevance in Malaria Disease in Children from Papua New Guinea [PDF]

, 2005
Malaria is a tremendous global public health problem. While especially hitting the poorest countries in the world, malaria elicits each year 300 million febrile illnesses and up to 1 million deaths. Widespread drug resistances, climatic changes, but also
Kästli, Mirjam Elisabeth
core   +1 more source

Capacity strengthening in malaria research: the Gates Malaria Partnership.

, 2006
The Gates Malaria Partnership (GMP) includes five African and four European partner institutions. Its research programme has five priority areas involving an extensive range of field-based studies.
Greenwood, Brian M, Bowler, Cathy H, Naylor, Heather, Bhasin, Amit, Targett, Geoffrey A   +4 more
core   +1 more source

Chloroquine/sulphadoxine-pyrimethamine for gambian children with malaria: transmission to mosquitoes of multidrug-resistant Plasmodium falciparum. [PDF]

, 2006
OBJECTIVES: In the Gambia, chloroquine (CQ) plus sulphadoxine-pyrimethamine (SP) is the first-line antimalarial treatment. Plasmodium falciparum parasites carrying mutations associated with resistance to each of these drugs were present in 2001 but did ...
Pinder Margaret, Jawara Musa, Targett Geoffrey A. T, Ord, Rosalynn, Hallett, Rachel L, Walraven, Gijs, Sutherland Colin J, Targett, Geoffrey AT, Alloueche Ali, Jawara, Musa, Dunyo, Samuel, Alexander Neal, Sutherland, Colin J, Randall, Anna, Walraven Gijs, Ord Rosalynn, Alexander, Neal, Hallett Rachel L, Dunyo Samuel, Pinder, Margaret, Alloueche, Ali, Randall Anna   +21 more
core   +1 more source

Schistosoma japonicum infection causes a reprogramming of glycolipid metabolism in the liver

Parasites & Vectors, 2019
Background Recent investigations indicate that schistosome infection is closely associated with aberrant glycolipid metabolism. However, the actual glycolipid metabolism gene expression, as well as the possible pathways that regulate glycolipid ...
Zhi-Peng Xu, Hao Chang, Yang-Yue Ni, Chen Li, Lin Chen, Min Hou, Min-Jun Ji   +6 more
doaj   +1 more source

Region‐Specific CD16+ Neutrophils Promote Colorectal Cancer Progression by Inhibiting Natural Killer Cells

Advanced Science
The colon is the largest compartment of the immune system, with innate immune cells exposed to antigens in the environment. However, the mechanisms by which the innate immune system is instigated are poorly defined in colorectal cancer (CRC).
Yan Zhang, Zien Wang, Yu Lu, David J. Sanchez, Jiaojiao Li, Linghao Wang, Xiaoxue Meng, Jianjun Chen, Tran Trung Kien, Ming Zhong, Wei‐Qiang Gao, Xianting Ding   +11 more
doaj   +1 more source

Addition of artesunate to chloroquine for treatment of Plasmodium falciparum malaria in Gambian children causes a significant but short-lived reduction in infectiousness for mosquitoes.

, 2004
OBJECTIVES: Combination therapy using existing anti-malarials together with artesunate (AS) has been advocated as a method to slow the spread of drug resistance.
Sutherland, Colin J, Obisike, Uche, Drakeley, Christopher J, Walraven, Gijs, Targett, Geoffrey AT, Jawara, Musa, Coleman, Rosalind, Pinder, Margaret   +7 more
core   +1 more source

Combination therapy counteracts the enhanced transmission of drug-resistant malaria parasites to mosquitoes.

, 2004
Malaria parasites carrying genes conferring resistance to antimalarials are thought to have a selective advantage which leads to higher rates of transmissibility from the drug-treated host.
Sutherland, Colin J, Drakeley, Chris J, Ord, Rosalynn, Hallett, Rachel L, Alexander, Neal, Walraven, Gijs, Targett, Geoffrey AT, Jawara, Musa, Pinder, Margaret, Alloueche, Ali   +9 more
core   +1 more source

CD36(OKM5)+ Dendritic Cells in the Oral Mucosal of HIV–and HIV+ Subjects

, 1991
In this study, we have investigated by light and electron microscopy the presence, distribution and inner structure of CD36(OKM5)+ dendritic cells (DC) in the lamina propria and epithelium of the oral mucosa of HIV–and HIV+ subjects; in the latter, both ...
Riccardi, Rossela, Ficarra, Giuseppe, Gaglioti, Domencio, Romagnoli, Paolo, Mori, Moira, Pimpinelli, Nicola, Borgognoni, Lorenzo   +6 more
core   +1 more source