Results 71 to 80 of about 9,756 (185)

The Gates Malaria Partnership: a consortium approach to malaria research and capacity development.

, 2012
Recently, there has been a major increase in financial support for malaria control. Most of these funds have, appropriately, been spent on the tools needed for effective prevention and treatment of malaria such as insecticide-treated bed nets, indoor ...
Greenwood, Brian, Targett, Geoffrey, Bhasin, Amit   +2 more
core   +1 more source

Artesunate reduces but does not prevent posttreatment transmission of Plasmodium falciparum to Anopheles gambiae.

, 2001
Combination therapy that includes artemisinin derivatives cures most falciparum malaria infections. Lowering transmission by reducing gametocyte infectivity would be an additional benefit.
Targett, G, Jawara, M, Doherty, T, Milligan, P, von Seidlein, L, Sutherland, C, Drakeley, C, Coleman, R, Pinder, M, Walraven, G, Deen, J   +10 more
core   +1 more source

Transforming growth factor beta 2 and heme oxygenase 1 genes are risk factors for the cerebral malaria syndrome in Angolan children. [PDF]

, 2010
BACKGROUND: Cerebral malaria (CM) represents a severe outcome of the Plasmodium falciparum infection. Recent genetic studies have correlated human genes with severe malaria susceptibility, but there is little data on genetic variants that increase the ...
Sambo, Maria Rosário, Carla Benchimol, Marques, Maria Isabel, Nuno Sepúlveda, Carlos Penha-Gonçalves, Maria Rosário Sambo, Maria Isabel Marques, Stefan Mustafa, Sepúlveda, Nuno, Sepúlveda Nuno, Gonçalves Lígia, Trovoada, Maria Jesus, Mustafa Stefan, Rute Velosa, Marques Maria Isabel, Velosa, Rute, António Coutinho, Benchimol, Carla, Vatúsia Quinhentos, Sambo Maria Rosário, Quinhentos Vatúsia, Oswald Wagner, Taane G Clark, Benchimol Carla, Penha-Gonçalves Carlos, Penha-Gonçalves, Carlos, Gonçalves, Lígia, Mustafa, Stefan, Coutinho, António, Maria Jesus Trovoada, Coutinho António, Clark Taane G., Lígia Gonçalves, Trovoada Maria Jesus, Quinhentos, Vatúsia, Wagner, Oswald, Wagner Oswald, Taane G. Clark, Clark, Taane G, Velosa Rute   +39 more
core   +1 more source

Malaria.

, 2005
Malaria is the most important parasitic infection in people, accounting for more than 1 million deaths a year. Malaria has become a priority for the international health community and is now the focus of several new initiatives.
Greenwood, Brian M, Bojang, Kalifa, Whitty, Christopher JM, Targett, Geoffrey AT   +3 more
core   +1 more source

In Human Dermis, Ultraviolet Radiation Induces Expansion of a CD36+ CD11b+ CD1- Macrophage Subset by Infiltration and Proliferation; CD1+ Langerhans-Like Dendritic Antigen-Presenting Cells are Concomitantly Depleted

Journal of Investigative Dermatology, 1995
Antigen-presenting (APC), suppressor T-cell-inducing macrophages infiltrate both human and murine epidermis after ultraviolet radiation (UVR) exposure. To determine their derivation, we prepared epidermal cell and dermal cell suspensions from human keratome biopsy specimens obtained from nonexposed skin and from UVB-irradiated sites (3 d after four ...
Meunier, Laurent, Bata-Csorgo, Zsuzsanna, Cooper, Kevin D.   +2 more
openaire   +2 more sources

Changes in monocyte subsets in volunteers who received an oral wild-type Salmonella Typhi challenge and reached typhoid diagnosis criteria

Frontiers in Immunology
An oral Controlled Human Infection Model (CHIM) with wild-type S. Typhi was re-established allowing us to explore the development of immunity. In this model, ~55% of volunteers who received the challenge reached typhoid diagnosis criteria (TD), while ~45%
Franklin R. Toapanta, Jingping Hu, Kari Ann Shirey, Paula J. Bernal, Myron M. Levine, Myron M. Levine, Thomas C. Darton, Claire S. Waddington, Andrew J. Pollard, Marcelo B. Sztein, Marcelo B. Sztein, Marcelo B. Sztein   +11 more
doaj   +1 more source

A new transfectant panel cell line‐based MoAb‐independent antigen capture assay system for detection of CD36 antibody

Vox Sanguinis, 2014
Background and ObjectivesCD36 antibody (Ab) causes several disorders: neonatal alloimmune thrombocytopenia, platelet transfusion refractoriness and non‐haemolytic transfusion reactions. However, there is no gold‐standard test for CD36 Ab.Materials and MethodsWe developed a transfectant panel cell line‐based MoAb‐independent antigen capture assay system
E, Amakishi, T, Hayashi, Y, Koh, N, Matsuyama, H, Ishii, H, Matsukura, K, Yasui, F, Hirayama   +7 more
openaire   +3 more sources

CD13 is a bona-fide marker of bovine pre-adipocytes with potential in cultivated fat applications

npj Science of Food
Despite its significant potential, cultivated fat manufacture remains a relatively inefficient process, as it primarily uses source preparations of animal-derived mesenchymal stem/stromal cells (MSC) that are poorly defined and highly heterogenous in ...
Seungmee Lee, Thomas Thrower, Susanna E. Riley, Cristina L. Esteves, F. Xavier Donadeu   +4 more
doaj   +1 more source

The epidemiology of Plasmodium falciparum gametocytes: weapons of mass dispersion.

, 2006
Much of the epidemiology of Plasmodium falciparum in Sub-Saharan Africa focuses on the prevalence patterns of asexual parasites in people of different ages, whereas the gametocytes that propagate the disease are often neglected.
Sauerwein, Robert W, Drakeley, Chris, Drakeley, C., Sutherland, C., Bousema, J Teun, Targett, Geoffrey AT, Bousema, J.T., Sauerwein, R.W., Sutherland, Colin, Targett, G.A.T.   +9 more
core   +1 more source

Seasonal carriage of pfcrt and pfmdr1 alleles in Gambian Plasmodium falciparum imply reduced fitness of chloroquine-resistant parasites.

, 2007
BACKGROUND: Observations in natural Plasmodium falciparum populations after removal of failing drugs suggest that there is a fitness cost of drug resistance.
Ord, Rosalynn, Jawara, Musa, Neal Alexander, Sam Dunyo, Sutherland, Colin J, Hallett, Rachel, Rachel Hallett, Alexander, Neal, Drakeley, Christopher J, Colin J. Sutherland, Dunyo, Sam, Rosalynn Ord, Musa Jawara, Geoffrey Targett, Targett, Geoffrey, Christopher J. Drakeley   +15 more
core   +1 more source