Spontaneous Remission of Blastic Plasmacytoid Dendritic Cell Neoplasm: A Case Report
MedicinaSpontaneous remissions (SRs) in blastic plasmacytoid dendritic cell neoplasms (BPDCNs) are infrequent, poorly documented, and transient. We report a 40-year-old man presenting with bycitopenia and soft tissue infection.
Tamara Castaño-Bonilla +8 more
doaj +1 more source
Induction of monocyte differentiation and foam cell formation in vitro by 7-ketocholesterol
Journal of Lipid Research, 2002 Oxidized LDL (OxLDL) is composed of many potentially proatherogenic molecules, including oxysterols. Of the oxysterols, 7-ketocholesterol (7-KC) is found in relatively large abundance in OxLDL, as well as in atherosclerotic plaque and foam cells in vivo.
John M. Hayden +6 more
doaj +1 more source
Radiotherapy and Immune System Interactions Historical Perspectives and Clinical Advancements
Molecular Carcinogenesis, EarlyView.ABSTRACT Radiotherapy (RT) has evolved significantly since its inception from treating benign conditions to becoming a cornerstone of cancer treatment. This review examines the complex interactions between RT and the immune system, highlighting its diverse effects on various immune cell populations, and exploring emerging strategies to enhance ...
Safiy Yahia +3 more
wiley +1 more source
CD36 c.1264 T>G Null Mutation Impairs Acquisition of IgG Antibodies to Plasmodium falciparum MSP1‐19 Antigen and is Associated with Higher Malaria Incidences in Tanzanian Children [PDF]
Scandinavian Journal of Immunology, 2012 AbstractPolymorphisms in genes that encode crucial signalling molecules have been proposed as factors that influence susceptibility to, and outcome of malaria. We studied the role of a mutation, c.1264 T>G, that causes CD36 deficiency on IgG responses to MSP‐119 antigen and malaria incidence. Children were genotyped for the c.1264 T>G mutation at
D, Kajeguka +7 more
openaire +2 more sources
Virulence of malaria is associated with differential expression of Plasmodium falciparum var gene subgroups in a case-control study [PDF]
, 2006 Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a major pathogenicity factor in falciparum malaria that mediates cytoadherence. PfEMP1 is encoded by approximately 60 var genes per haploid genome.
Baea, Kay +5 more
core +1 more source
Med Research, EarlyView.ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang +22 more
wiley +1 more source
Schistosoma japonicum infection causes a reprogramming of glycolipid metabolism in the liver
Parasites & Vectors, 2019 Background Recent investigations indicate that schistosome infection is closely associated with aberrant glycolipid metabolism. However, the actual glycolipid metabolism gene expression, as well as the possible pathways that regulate glycolipid ...
Zhi-Peng Xu +6 more
doaj +1 more source
Loss of synchronized retinal phagocytosis and age-related blindness in mice lacking alphavbeta5 integrin. [PDF]
, 2004 Daily phagocytosis by the retinal pigment epithelium (RPE) of spent photoreceptor outer segment fragments is critical for vision. In the retina, early morning circadian photoreceptor rod shedding precedes synchronized uptake of shed photoreceptor ...
Brodie, Scott E +5 more
core +1 more source
The Gates Malaria Partnership: a consortium approach to malaria research and capacity development.
, 2012 Recently, there has been a major increase in financial support for malaria control. Most of these funds have, appropriately, been spent on the tools needed for effective prevention and treatment of malaria such as insecticide-treated bed nets, indoor ...
Bhasin, Amit +2 more
core +1 more source
The regulation of B cell responses in systemic autoimmunity [PDF]
, 2017 Our immune system is a complex network made up of physical barriers and specialized proteins, cells and organs that all work together to prevent pathogens from causing disease in the body.
Duhlin, Amanda
core +1 more source