Background The efficacy of highly active antiretroviral therapy (HAART) determined by simultaneous monitoring over 100 cell-surface antigens overtime has not been attempted.
Wang Bin +5 more
doaj +1 more source
Functions of two distinct Kupffer cells in the liver
Tissue-resident macrophages play critically important roles in host homeostasis and pathogenesis of diseases, with the functions of phagocytosis, metabolism, and immune modulation.
Chunye Zhang, Shuai Liu, Ming Yang
doaj +1 more source
Parasite infectivity and immunity to Plasmodium falciparum gametocytes in Gambian children. [PDF]
Immunity to the sexual stages of Plasmodium falciparum can be induced during natural infections. Characterization of this immunity may facilitate the design of a transmission-blocking vaccine (TBV).
Bousema, T. +13 more
core +1 more source
Comparison of schistosoma mansoni soluble cercarial antigens and soluble egg antigens for serodiagnosing schistosome infections [PDF]
A Schistosoma mansoni cercarial antigen preparation (cercarial transformation fluid – SmCTF) was evaluated for detection of anti-schistosome antibodies in human sera in 4 collaborating laboratories.
Dawson, E. +40 more
core +2 more sources
The role and mechanism of action of endoplasmic reticulum transmembrane protein 166 in liver lipid metabolism [PDF]
Objective To investigate the role and specific molecular mechanism of action of endoplasmic reticulum transmembrane protein 166 (TMEM166) in liver lipid metabolism. Methods Tmem166flox/flox mice were crossed with Alb-Cre mice, and the offspring Tmem166+/+
LI Lianhui, YANG Di, ZANG Kailai, SUN Yani, DU Qiyuan, LI Ning
doaj +1 more source
Phenotypic and functional changes in blood monocytes following adherence to endothelium. [PDF]
ObjectiveBlood monocytes are known to express endothelial-like genes during co-culture with endothelium. In this study, the time-dependent change in the phenotype pattern of primary blood monocytes after adhering to endothelium is reported using a novel ...
Colin Tso, Kerry-Anne Rye, Philip Barter
doaj +1 more source
CD36-ir at cardiomyocyte intercalated discs was significantly increased by PPARγ activation.
(A-C) Photomicrographs of left ventricle cardiomyocytes immunostained for CD36 in the (A) control, (B) 6-OHDA + placebo, and (C) 6-OHDA + pioglitazone groups. Scale bar = 50 μm. Arrowheads point to CD36-ir at intercalated discs.
Viktoriya Bondarenko (319083) +8 more
core +1 more source
Immunity to Intracellular Salmonella Depends on Surface-associated Antigens [PDF]
Invasive Salmonella infection is an important health problem that is worsening because of rising antimicrobial resistance and changing Salmonella serovar spectrum.
Rizos Konstantin +50 more
core +2 more sources
PPARα modulation of macrophage polarization and inflammatory signaling in mimic periodontitis [PDF]
Objective This study investigates the role of peroxisome proliferator-activated receptor alpha (PPARα) in regulating macrophage polarization and inflammatory signaling under stimulation by periodontal pathogens.
HU Arthur, Yvette Y CHEN
doaj +1 more source
Background: Endemic Burkitt lymphoma (eBL) is an aggressive childhood B-cell lymphoma linked to Plasmodium falciparum (Pf) malaria in sub-Saharan Africa.
Andriy Derkach +19 more
doaj +1 more source

