Knob-independent cytoadherence of Plasmodium falciparum to the leukocyte differentiation antigen CD36. [PDF]
The Journal of experimental medicine, 1990 The survival of Plasmodium falciparum-infected erythrocytes is enhanced by the sequestration of mature trophozoites and schizonts from the peripheral circulation. Cytoadherence of infected erythrocytes in vivo is associated with the presence of knobs on the erythrocyte surface, but we and others have shown recently that cytoadherence to C32 melanoma ...
BIGGS, BA +8 more
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Overcoming β-Cell Dysfunction in Type 2 Diabetes Mellitus: CD36 Inhibition and Antioxidant System [PDF]
Diabetes & Metabolism JournalType 2 diabetes mellitus (T2DM) is marked by chronic hyperglycemia, gradually worsening β-cell failure, and insulin resistance. Glucotoxicity and oxidative stress cause β-cell failure by increasing reactive oxygen species (ROS) production, impairing ...
Il Rae Park +2 more
doaj +1 more source
Immunomodulatory cross-talk between conjunctival goblet cells and dendritic cells. [PDF]
PLoS ONE, 2015 Goblet cells are secretory epithelial cells of mucosal tissues that confer protection from environmental agents or pathogens via expression and secretion of soluble mucins.
Laura Contreras-Ruiz, Sharmila Masli
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Antigenic and functional differences in adhesion of Plasmodium falciparum-infected erythrocytes to human and bovine CD36 [PDF]
Infection and Immunity, 1993 Cytoadherence by Plasmodium falciparum-infected erythrocytes (PRBC) to microvascular endothelium is, in part, mediated by the specific interaction between a parasite-derived erythrocyte surface ligand and a specific binding site on human CD36. We describe the selection for increased adhesion of PRBC to bovine CD36 and demonstrate that the molecular ...
C F, Ockenhouse +3 more
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Frontiers in Cellular and Infection Microbiology, 2023 We previously demonstrated that brain-resident cells produce IFN-γ in response to reactivation of cerebral infection with Toxoplasma gondii. To obtain an overall landscape view of the effects of IFN-γ from brain-resident cells on the cerebral protective ...
Yasuhiro Suzuki +6 more
doaj +1 more source
Functions of two distinct Kupffer cells in the liver
Exploration of Medicine, 2021 Tissue-resident macrophages play critically important roles in host homeostasis and pathogenesis of diseases, with the functions of phagocytosis, metabolism, and immune modulation.
Chunye Zhang, Shuai Liu, Ming Yang
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Sympatric Plasmodium falciparum isolates from Venezuela have structured var gene repertoires. [PDF]
, 2003 BACKGROUND: The human malaria parasite Plasmodium falciparum expresses adhesins belonging to the erythrocyte membrane protein 1 (PfEMP1) family on the surface of the infected host erythrocyte.
Sutherland, Colin J +9 more
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Retrovirology, 2008 Background The efficacy of highly active antiretroviral therapy (HAART) determined by simultaneous monitoring over 100 cell-surface antigens overtime has not been attempted.
Wang Bin +5 more
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Seroepidemiological and parasitological evaluation of the heterogeneity of malaria infection in the Gambia. [PDF]
, 2013 BACKGROUND: As countries make progress in malaria control, transmission may be reduced to such an extent that few cases occur, and identification of the remaining foci of transmission may require a combination of surveillance tools.
David J Conway +11 more
core +1 more source
Sub-grouping of
, 2003 Background The variant surface antigen family Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP1) is an important target for protective immunity and is implicated in the pathology of malaria through its ability to adhere to host endothelial ...
Jensen Anja TR +9 more
core +1 more source