Results 11 to 20 of about 182,736 (214)

Cytoadherence and virulence - the case of Plasmodium knowlesi malaria [PDF]

Malaria Journal, 2012
Background Cytoadherence of infected red blood cells to brain endothelium is causally implicated in malarial coma, one of the severe manifestations of falciparum malaria.
Fatih Farrah A, Siner Angela, Ahmed Atique, Woon Lu, Craig Alister G, Singh Balbir, Krishna Sanjeev, Cox-Singh Janet   +7 more
doaj   +2 more sources

CD36 deficiency in mice impairs lipoprotein lipase-mediated triglyceride clearance [PDF]

, 2005
CD36 is involved in high-affinity peripheral FFA uptake. CD36-deficient (cd36-/-) mice exhibit increased plasma FFA and triglyceride (TG) levels. The aim of the present study was to elucidate the cause of the increased plasma TG levels in cd36-/- mice ...
Romijn, Johannes A., Romijn, J A, Havekes, Louis M., oer, M.A.M. den, Febbraio, M, Havekes, L.M., Febbraio, Maria, Voshol, Peter J., Rensen, Patrick C. N., Febbraio, M., Goudriaan, J R, Kuipers, F., Goudriaan, J.R., Goudriaan, Jeltje R., Voshol, P.J., Voshol, P J, Kuipers, F, Romijn, J.A., Rensen, P.C.N., Havekes, L M, Kuipers, F; id_orcid, Kuipers, Folkert, Rensen, P C N, den Boer, Marion A. M., den Boer, M A M   +24 more
core   +2 more sources

Positive selection of a CD36 nonsense variant in sub-Saharan Africa, but no association with severe malaria phenotypes. [PDF]

, 2009
The prevalence of CD36 deficiency in East Asian and African populations suggests that the causal variants are under selection by severe malaria. Previous analysis of data from the International HapMap Project indicated that a CD36 haplotype bearing a ...
Jallow, Muminatou, Palma, Alejandro, Jeffreys, Anna E, Michael J. Griffiths, Fry, Andrew Evan, Teo, Yik Y, Taylor, Terrie E., Kerrin S. Small, Fry, A. E., Fry, Andrew E., Williams, T. N., Diakite, M, Palma, A., Oduro, Abraham R., Newton, C. R., Kwiatkowski, DP, Anna E. Jeffreys, Pinder, M., Jeffreys, AE, Kwadwo A. Koram, Fry, AE, Kwiatkowski, Dominic, Sisay-Joof, Fatou, Williams, Thomas N., Kirk A. Rockett, Clark, Taane G., Wilson, Jonathan, Rockett, KA, Koram, KA, Abraham R. Oduro, Dominic P. Kwiatkowski, Mahamadou Diakite, Yik Y. Teo, Ghansa, A., Jeffreys, A. E., Kwiatkowski, Dominic P., Campino, S, Anita Ghansa, Taane G. Clark, Koram, Kwadwo, Clark, Taane G, Clark, TG, Malcolm E. Molyneux, Molyneux, Malcolm E, Thomas N. Williams, Ghansa, Anita, Green, Angela, Kevin Marsh, Griffiths, Michael J., Small, Kerrin S, Fatou Sisay-Joof, Pinder, M, Taylor, T. E., Clark, T. G., Susana Campino, Auburn, S., Norbert Peshu, Sarah Auburn, Pardis C. Sabeti, Diakite, Mahamadou, Rockett, Kirk A, Sabeti, PC, Rogers, WO, Oduro, Abraham R, Molyneux, Malcolm E., Jallow, M, Marsh, K, Teo, Yik Y., Small, K. S., Campino, S., Rogers, W. O., Green, A., Koram, Kwadwo A., Marsh, Kevin, Pinder, Margaret, Small, Kerrin S., Angela Green, Oduro, AR, Andrew E. Fry, Teo, YY, Teoh, Yin Yoong Jimmy, Kwiatkowski, D. P., Palma, A, Jonathan Wilson, Peshu, N, Alejandro Palma, Williams, TN, Taylor, Terrie E, Griffiths, M. J., Rockett, K. A., Green, A, William O. Rogers, Terrie E. Taylor, Koram, K. A., Sabeti, Pardis C., Sisay-Joof, F, Newton, Charles R., Teo, Y. Y., Molyneux, ME, Rogers, William O, Oduro, A. R., Peshu, N., Rockett, Kirk A., Jeffreys, Anna E., Auburn, Sarah, Diakite, M., Wilson, J., Auburn, S, Koram, Kwadwo A, Griffiths, MJ, Griffiths, Michael J, Newton, Charles R, Muminatou Jallow, Fry, Andrew E, Small, KS, Newton, CR, Jallow, M., Peshu, Norbert, Campino, Susana, Sabeti, Pardis, Sabeti, P. C., Sisay-Joof, F., Williams, Thomas N, Rogers, William O., Taylor, TE, Wilson, J, Charles R. Newton, Ghansa, A, Margaret Pinder, Williams, Thomas, Sabeti, Pardis C, Kwiatkowski, Dominic P   +131 more
core   +1 more source

Plasmodium falciparum antigens on the surface of the gametocyte-infected erythrocyte. [PDF]

, 2008
BACKGROUND: The asexual blood stages of the human malaria parasite Plasmodium falciparum produce highly immunogenic polymorphic antigens that are expressed on the surface of the host cell.
Christopher J. Drakeley, Saeed Maha, Saeed, Maha, Alexander Neal, Saeed, M., Geoffrey A T Targett, Sutherland, Colin J, Drakeley Christopher J., Targett Geoffrey A. T., Roeffen Will, Geoffrey A. T. Targett, Colin J. Sutherland, Targett, Geoffrey AT, Alexander, N., Neal Alexander, Colin J Sutherland, Sutherland Colin J., Targett, G.A.T., Roeffen, W.F.G., Roeffen, Will, Maha Saeed, Alexander, Neal, Drakeley, Christopher J, Drakeley, C., Will Roeffen, Christopher J Drakeley, Sutherland, C.J.   +26 more
core   +2 more sources

CD36 deficiency increases insulin sensitivity in muscle, but induces insulin resistance in the liver in mice [PDF]

, 2003
CD36 (fatty acid translocase) is involved in high-affinity peripheral fatty acid uptake. Mice lacking CD36 exhibit increased plasma free fatty acid and triglyceride (TG) levels and decreased glucose levels.
Maassen, J.A., Voshol, P.J., Romijn, Johannes A., Teusink, Bas, Romijn, J.A., Havekes, Louis M., Maassen, J. Anton, Dahlmans, V.E.H., Dahlmans, Vivian E. H., Havekes, L.M., Febbraio, Maria, Voshol, Peter J., Febbraio, M., Ouwens, D.M., Teusink, B., Goudriaan, J.R., Goudriaan, Jeltje R., Ouwens, D. Margriet   +17 more
core   +1 more source

Alpha (v) integrins license regulatory T cells to apoptotic cells and self-associated antigens [PDF]

, 2010
Defects in apoptotic cell clearance are thought to contribute to autoimmunity by failure to induce tolerance, coupled with accumulation of immunogenic material.
Paidassi, Helena, Lacy-Hulbert, Adam, Helena Païdassi, Adam Lacy-Hulbert, Mridu Acharya, Acharya, Mridu   +5 more
core   +1 more source

Alterations in Lysosome Homeostasis in Lipid-Related Disorders: Impact on Metabolic Tissues and Immune Cells

Frontiers in Cell and Developmental Biology, 2021
Lipid-related disorders, which primarily affect metabolic tissues, including adipose tissue and the liver are associated with alterations in lysosome homeostasis.
Fernanda Cabrera-Reyes, Fernanda Cabrera-Reyes, Claudia Parra-Ruiz, Claudia Parra-Ruiz, María Isabel Yuseff, Silvana Zanlungo   +5 more
doaj   +1 more source

Immunomodulatory cross-talk between conjunctival goblet cells and dendritic cells. [PDF]

PLoS ONE, 2015
Goblet cells are secretory epithelial cells of mucosal tissues that confer protection from environmental agents or pathogens via expression and secretion of soluble mucins.
Laura Contreras-Ruiz, Sharmila Masli
doaj   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

IFN-γ production by brain-resident cells activates cerebral mRNA expression of a wide spectrum of molecules critical for both innate and T cell-mediated protective immunity to control reactivation of chronic infection with Toxoplasma gondii

Frontiers in Cellular and Infection Microbiology, 2023
We previously demonstrated that brain-resident cells produce IFN-γ in response to reactivation of cerebral infection with Toxoplasma gondii. To obtain an overall landscape view of the effects of IFN-γ from brain-resident cells on the cerebral protective ...
Yasuhiro Suzuki, Jenny Lutshumba, Kuey Chu Chen, Kuey Chu Chen, Mohamed H. Abdelaziz, Qila Sa, Eri Ochiai   +6 more
doaj   +1 more source