Immature Dendritic Cells Phagocytose Apoptotic Cells via αvβ5 and CD36, and Cross-present Antigens to Cytotoxic T Lymphocytes [PDF]
Dendritic cells, but not macrophages, efficiently phagocytose apoptotic cells and cross-present viral, tumor, and self-antigens to CD8+ T cells. This in vitro pathway corresponds to the in vivo phenomena of cross-priming and cross-tolerance. Here, we demonstrate that phagocytosis of apoptotic cells is restricted to the immature stage of dendritic cell (
Albert, M +6 more
openaire +6 more sources
Transfer of Cell-Surface Antigens by Scavenger Receptor CD36 Promotes Thymic Regulatory T Cell Receptor Repertoire Development and Allo-tolerance [PDF]
The development of T cell tolerance in the thymus requires the presentation of host proteins by multiple antigen-presenting cell (APC) types. However, the importance of transferring host antigens from transcription factor AIRE-dependent medullary thymic epithelial cells (mTECs) to bone marrow (BM) APCs is unknown.
Perry, Justin SA +14 more
openaire +8 more sources
CD36 family members are TCR-independent ligands for CD1 antigen–presenting molecules [PDF]
CD1 molecules bind CD36 family members, and blocking this interaction facilitates staining and study of CD1-restricted T cells.
Nicholas A. Gherardin +16 more
openaire +5 more sources
Expression of the myelomonocytic antigens L1 and CD36 in human epidermis [PDF]
Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/74721/1/j.1365-2133.1990.tb01466.x ...
Barker, Jonathan N.W.N. +4 more
openaire +3 more sources
Knob-independent cytoadherence of Plasmodium falciparum to the leukocyte differentiation antigen CD36. [PDF]
The survival of Plasmodium falciparum-infected erythrocytes is enhanced by the sequestration of mature trophozoites and schizonts from the peripheral circulation. Cytoadherence of infected erythrocytes in vivo is associated with the presence of knobs on the erythrocyte surface, but we and others have shown recently that cytoadherence to C32 melanoma ...
BIGGS, BA +8 more
openaire +3 more sources
Nanoparticles Containing Curcumin Useful for Suppressing Macrophages In Vivo in Mice. [PDF]
To explore a novel method using liposomes to suppress macrophages, we screened food constituents through cell culture assays. Curcumin was one of the strongest compounds exhibiting suppressive effects on macrophages. We subsequently tried various methods
Chie Amano +6 more
doaj +1 more source
Dendritic cells in plasmodium infection [PDF]
Infection with Plasmodium parasites (malaria) contributes greatly to morbidity and mortality in affected areas. Interaction of the protozoan with the immune system has a critical role in the pathogenesis of the disease, but may also hold a key to ...
Alonso +15 more
core +2 more sources
Endothelial cell CD36 (glycoprotein IV) has been purified from bovine heart tissue by detergent partitioning and immunoaffinity chromatography. Bovine CD36 differs from human CD36 in its apparent mass (85 versus 88 kDa), primary structure, and immunological cross-reactivity.
D E, Greenwalt +4 more
openaire +2 more sources
Lipid-related disorders, which primarily affect metabolic tissues, including adipose tissue and the liver are associated with alterations in lysosome homeostasis.
Fernanda Cabrera-Reyes +5 more
doaj +1 more source
Overcoming β-Cell Dysfunction in Type 2 Diabetes Mellitus: CD36 Inhibition and Antioxidant System [PDF]
Type 2 diabetes mellitus (T2DM) is marked by chronic hyperglycemia, gradually worsening β-cell failure, and insulin resistance. Glucotoxicity and oxidative stress cause β-cell failure by increasing reactive oxygen species (ROS) production, impairing ...
Il Rae Park +2 more
doaj +1 more source

