Results 1 to 10 of about 15,256,107 (329)

Targeted Lysosomal Degradation of Extracellular and Membrane Proteins: From Receptor Hijacking to Programmable Endolysosomal Routing. [PDF]

Adv Sci (Weinh)
Targeted chimeric degraders engage extracellular or membrane proteins and endocytosable cell‐surface receptors, forming ternary complexes that induce receptor‐mediated internalization. Following endocytosis, post‐endocytic sorting—not internalization alone—determines target fate.
Liu K, Wang X, Liu X, He C, Qian D, Meng X, Zhu L.   +6 more
europepmc   +2 more sources

PCSK9-Mediated Inflammation in Foam Cell Formation and Exploring the Biologically Active Compounds Derived From Natural Resources. [PDF]

Adv Pharmacol Pharm Sci
Wisesa MHM, Mathriul AQ, Suswidiantoro V, Puteri MU, Kato M, Idris MHM, Saputri FC.   +6 more
europepmc   +1 more source

Artemisinin-Related Therapeutic Strategies for Autoimmune Thyroiditis: Chemokine-Receptor Networks, Spatial Thyroid Biology, and Molecular Mechanisms. [PDF]

Drug Des Devel Ther
Sun Y, Yang X, Zhu Q, Yang R.
europepmc   +1 more source

Scavenger Receptor Class B Is Required for Hepatitis C Virus Uptake and Cross-Presentation by Human Dendritic Cells

Journal of Virology, 2008
H. Barth, E. Schnober, C. Neumann-Haefelin, C. Thumann, M. Zeisel, H. Diepolder, Zong-Yi Hu, T. Liang, H. Blum, R. Thimme, M. Lambotin, T. Baumert   +11 more
semanticscholar   +1 more source

A nucleic acid labeling chemistry reveals surface DNA on exosomes. [PDF]

Proc Natl Acad Sci U S A
Bošković F, Dutta Gupta P, Zhang J, Krishnan Y, Szostak JW.   +4 more
europepmc   +1 more source

Antigen-specific tolerance and control of autoimmunity effected by liver sinusoidal endothelial cells is unimpaired in liver fibrosis. [PDF]

Front Immunol
Gottwick C, Averhoff P, Casar C, Liebig LA, Pilz SM, Haas V, Krzikalla D, Fleischer S, Hübner N, Adlung L, Schwinge D, Schramm C, Carambia A, Herkel J.   +13 more
europepmc   +1 more source

CD36, a class B scavenger receptor, is expressed on microglia in Alzheimer's disease brains and can mediate production of reactive oxygen species in response to beta-amyloid fibrils.

American Journal of Pathology, 2002
Indra Sethy Coraci, J. Husemann, J. Berman, C. Hulette, Jennifer H. Dufour, Gabriele K. Campanella, A. Luster, S. Silverstein, J. E. El Khoury   +8 more
semanticscholar   +1 more source

From Genes to Pathways: The Molecular Landscape of Systemic Lupus Erythematosus. [PDF]

Int J Mol Sci
Rashid R, Ramirez-Ortiz ZG.
europepmc   +1 more source

IL-6 triggers lysosomal degradation of LDL-R and enhances LDL-C uptake in vascular endothelial cells via macropinocytosis. [PDF]

Mol Med
Zegeye MM, Veettil JT, Paramel GV, Kurt S, Salihovic S, Ljungberg LU, Kumawat AK, Sirsjö A.   +7 more
europepmc   +1 more source

Association of LDLR and SCARB1 gene polymorphisms with hepatocellular carcinoma: a case-control study proposing a 'double-hit' model. [PDF]

Lipids Health Dis
Altintas Z, Cevik MO, Derici Eker E, Altintas E.   +3 more
europepmc   +1 more source