Results 1 to 10 of about 23,795 (167)
Insights into binding of S100 proteins to scavenger receptors: class B scavenger receptor CD36 binds S100A12 with high affinity. [PDF]
Amino Acids, 2017 The EF-hand type calcium-binding protein S100A12 exerts numerous intra- and extracellular functions of (patho)physiological relevance. Therefore, receptors of S100A12 are of high interest for research and clinical applications. Beside the extensively studied receptor for advanced glycation endproducts (RAGE), G-protein coupled receptors and more ...
Tondera C, Laube M, Pietzsch J.
europepmc +5 more sources
Scavenger receptor class B type I as a receptor for oxidized low density lipoprotein [PDF]
Journal of Lipid Research, 2001 Scavenger receptor class B type I (SR-BI) has been established as the primary mediator of the selective transfer of lipids from HDL to mammalian cells.
Kristin Gillotte-Taylor +4 more
doaj +3 more sources
Journal of Lipid Research, 2007 Modified forms of LDL, including oxidized low density lipoprotein (OxLDL), contribute to macrophage lipid accumulation in the vessel wall. Despite the pathophysiological importance of uptake pathways for OxLDL, the molecular details of OxLDL endocytosis ...
Bing Sun +5 more
doaj +3 more sources
Loss of Function of Scavenger Receptor SCAV-5 Protects C. elegans Against Pathogenic Bacteria
Frontiers in Cellular and Infection Microbiology, 2021 Scavenger receptors play a critical role in innate immunity by acting as the pattern-recognition receptors. There are six class B scavenger receptors homologs in C. elegans.
Aixiao Luo +5 more
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Scavenger receptor class B type I: a multifunctional receptor [PDF]
Annals of the New York Academy of Sciences, 2011 The scavenger receptor class B type I (SR‐B1) plays an important role in meditating the uptake of HDL‐derived cholesterol and cholesteryl ester in the liver and steroidogenic tissues. In addition to being ubiquitous, SR‐B1 is a high‐density lipoprotein (HDL) receptor in many tissues, though the mechanism by which SR‐B1 does this is unclear.
VALACCHI, Giuseppe +3 more
openaire +3 more sources
The class A scavenger receptor SR-A/CD204 and the class B scavenger receptor CD36 regulate immune functions of macrophages differently [PDF]
Innate Immunity, 2013 SR-A/CD204 and CD36 are major receptors responsible for oxidized lipoproteins uptake by macrophages in atherosclerotic plaques. Both receptors also share the role as receptors for different pathogens, but studies on their signaling have been hampered by the lack of selective ligands. We report that, upon specific ligation by Ab, SR-
Józefowski, Szczepan +4 more
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A gut feeling for drugs that have metabolic benefits
Nature Communications, 2023 Resveratrol (REV) is a natural polyphenol with anti-obesity effects. However, the mechanisms remain unclear due to its low bioavailability and the lack of defined membrane-bound or nuclear receptors.
Eryun Zhang, Alon Agua, Wendong Huang
doaj +1 more source
Regulation of Platelet Function by Class B Scavenger Receptors in Hyperlipidemia [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2010 Platelets constitutively express class B scavenger receptors CD36 and SR-BI, 2 closely related pattern recognition receptors best known for their roles in lipoprotein and lipid metabolism. The biological role of scavenger receptors in platelets is poorly understood.
Alejandro, Zimman, Eugene A, Podrez
openaire +2 more sources
Journal of Lipid Research, 2012 There is a tight relationship between fertility and changes in cholesterol metabolism during spermatogenesis. In the testis, class B scavenger receptors (SR-B) SR-BI, SR-BII, and LIMP II mediate the selective uptake of cholesterol esters from HDL, which ...
María Emilia Casado +8 more
doaj +1 more source
The Class B Scavenger Receptors SR-BI and CD36 Are Receptors for Anionic Phospholipids [PDF]
Journal of Biological Chemistry, 1995 The specific recognition of anionic phospholipids in the outer leaflets of cell membranes and lipoproteins by cell surface receptors may play an important role in a variety of physiologic and pathophysiologic processes (e.g. recognition of damaged or senescent cells by the reticuloendothelial system or lipoprotein homeostasis).
A, Rigotti, S L, Acton, M, Krieger
openaire +2 more sources