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Scavenger Receptors and Atherosclerosis
Biological Research, 2000 Scavenger receptors were discovered as cell surface proteins capable of binding and internalization of modified lipoproteins. These receptors exhibit a broad ligand binding specificity including potential physiological and pathophysiological ligands ...
ATTILIO RIGOTTI
doaj +2 more sources
Scavenger Receptor Class B Type I Is a Plasma Membrane Cholesterol Sensor [PDF]
Circulation Research, 2013 Rationale: Signal initiation by the high-density lipoprotein (HDL) receptor scavenger receptor class B, type I (SR-BI), which is important to actions of HDL on endothelium and other processes, requires cholesterol efflux and the C-terminal transmembrane domain.
Etienne Morel +2 more
exaly +3 more sources
SR-B1 knockdown suppresses breast cancer cell proliferation, migration, and invasion via the PI3K/AKT pathway [PDF]
Einstein (São Paulo)Background The role of scavenger receptor class B type 1 (SR-B1) in breast cancer remains largely unknown. Objective This study aimed to investigate the effects of SR-B1 on breast cancer cell proliferation, migration, and invasion and to elucidate the
Ming Li, Yanmei Xu, Jinwen Li, Juan Li
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A class B scavenger receptor mediates the cellular uptake of carotenoids in Drosophila [PDF]
Proceedings of the National Academy of Sciences, 2002 Carotenoids are currently being intensely investigated regarding their potential to lower the risk of chronic disease and vitamin A deficiency. Invertebrate models in which vitamin A deficiency is not lethal allow the isolation of blind but viable mutants affected in the pathway leading from dietary carotenoids to vitamin A.
Cornelia Kiefer +3 more
semanticscholar +3 more sources
Soluble CD5 and CD6: Lymphocytic Class I Scavenger Receptors as Immunotherapeutic Agents
Cells, 2020 CD5 and CD6 are closely related signal-transducing class I scavenger receptors mainly expressed on lymphocytes. Both receptors are involved in the modulation of the activation and differentiation cell processes triggered by clonotypic antigen-specific ...
María Velasco-de Andrés +5 more
doaj +3 more sources
Journal of Lipid Research, 2015 Scavenger receptors (SRs) like cluster determinant 36 (CD36) and SR class B type I (SR-BI) play a debated role in lipid transport across the intestinal brush border membrane. We used surface plasmon resonance to analyze real-time interactions between the
Aurélie Goncalves +6 more
doaj +2 more sources
Uptake and fate of class B scavenger receptor ligands in HepG2 cells.
European Journal of Biochemistry, 1999 Class B scavenger receptors (SR‐Bs) interact with native, acetylated and oxidized low‐density lipoprotein (LDL, AcLDL and OxLDL), high‐density lipoprotein (HDL3) and maleylated BSA (M‐BSA). The aim of this study was to analyze the catabolism of CD36‐ and LIMPII‐analogous‐1 (CLA‐1), the human orthologue for the scavenger receptor class B type I (SR‐BI),
D. Rhainds +3 more
semanticscholar +3 more sources
Contribution of receptors to 'Neisseria meningitidis' interactions with human macrophages [PDF]
, 2004 N. meningitidis is a gram-negative human pathogen that invades human cells, evades immune responses and goes on to cause meningococcal disease, sepsis and death.
Abdillahi, Fatumo Abdi
core +6 more sources
Loss of Function of Scavenger Receptor SCAV-5 Protects C. elegans Against Pathogenic Bacteria
Frontiers in Cellular and Infection Microbiology, 2021 Scavenger receptors play a critical role in innate immunity by acting as the pattern-recognition receptors. There are six class B scavenger receptors homologs in C. elegans.
Aixiao Luo +5 more
doaj +1 more source
Scavenger receptor class B type I: a multifunctional receptor [PDF]
Annals of the New York Academy of Sciences, 2011 The scavenger receptor class B type I (SR‐B1) plays an important role in meditating the uptake of HDL‐derived cholesterol and cholesteryl ester in the liver and steroidogenic tissues. In addition to being ubiquitous, SR‐B1 is a high‐density lipoprotein (HDL) receptor in many tissues, though the mechanism by which SR‐B1 does this is unclear.
VALACCHI, Giuseppe +3 more
openaire +3 more sources