Results 21 to 30 of about 24,292 (301)

The Past and Present Lives of the Intraocular Transmembrane Protein CD36

Cells, 2022
Cluster of differentiation 36 (CD36) belongs to the B2 receptors of the scavenger receptor class B family, which is comprised of single-chain secondary transmembrane glycoproteins.
Rucui Yang, Qingping Liu, Mingzhi Zhang
doaj   +1 more source

Scavenger receptor BI (SR-BI) mediates free cholesterol flux independently of HDL tethering to the cell surface

Journal of Lipid Research, 1999
In addition to its effect on high density lipoprotein (HDL) cholesteryl ester (CE) uptake, scavenger receptor BI (SR-BI) was recently reported to stimulate free cholesterol (FC) flux from Chinese hamster ovary (CHO) cells stably expressing mouse SR-BI, a
Margarita de la Llera-Moya, George H. Rothblat, Margery A. Connelly, Ginny Kellner-Weibel, Sana W. Sakr, Michael C. Phillips, David L. Williams   +6 more
doaj   +1 more source

Sterol regulation of scavenger receptor class B type I in macrophages [PDF]

Journal of Lipid Research, 2004
Scavenger receptor class B type I (SR-BI) is expressed in macrophages, but its role in sterol trafficking in these cells remains controversial. We examined the effect of sterol loading on SR-BI expression in human monocytes/macrophages, mouse peritoneal macrophages, and a cultured mouse macrophage cell line (J774 cells).
Liqing Yu, Guoqing Cao, Joyce Repa, Herbert Stangl   +3 more
openaire   +3 more sources

Targeting SR-BI for cancer diagnostics, imaging and therapy

Frontiers in Pharmacology, 2016
Scavenger receptor class B type I (SR-BI) plays an important role in trafficking cholesteryl esters between the core of high density lipoprotein and the liver. Interestingly, this integral membrane protein receptor is also implicated in the metabolism of
Maneesha Amrita Rajora, Maneesha Amrita Rajora, Gang Zheng, Gang Zheng, Gang Zheng   +4 more
doaj   +1 more source

Targeting Early Dementia: Using Lipid Cubic Phase Nanocarriers to Cross the Blood–Brain Barrier

Biomimetics, 2018
Over the past decades, a frequent co-morbidity of cerebrovascular pathology and Alzheimer’s disease has been observed. Numerous published studies indicate that the preservation of a healthy cerebrovascular endothelium can be an important therapeutic ...
Joseph S. D’Arrigo
doaj   +1 more source

Scavenger receptor B2 as a receptor for hand, foot and Mouth disease and severe neurological diseases

Frontiers in Microbiology, 2012
Enterovirus 71 (EV71) is one of the major causative agents of hand, foot and mouth disease (HFMD). Infection with EV71 is occasionally associated with severe neurological diseases such as acute encephalitis, acute flaccid paralysis and cardiopulmonary ...
Seiya eYamayoshi, Ken eFujii, Satoshi eKoike   +2 more
doaj   +1 more source

SR-BI-directed HDL-cholesteryl ester hydrolysis

Journal of Lipid Research, 2003
We have examined the metabolic fate of HDL cholesteryl ester (CE) delivered to cells expressing scavenger receptor class B type I (SR-BI). Comparison of SR-BI with a related class B scavenger receptor, CD36, showed a greater uptake and a more rapid and ...
Margery A. Connelly, Ginny Kellner-Weibel, George H. Rothblat, David L. Williams   +3 more
doaj   +1 more source

CD36, a Member of the Class B Scavenger Receptor Family, as a Receptor for Advanced Glycation End Products [PDF]

Journal of Biological Chemistry, 2001
Abstract: Interaction of advanced glycation end products (AGE) with AGE‐receptors induces several cellular phenomena relating potentially to diabetic complications. Five AGE‐receptors identified so far are RAGE (receptor for AGE), 80 K‐H, OST‐48, galectin‐3, and SR‐A (macrophage scavenger receptor type I and II).
N, Ohgami, R, Nagai, M, Ikemoto, H, Arai, A, Kuniyasu, S, Horiuchi, H, Nakayama   +6 more
openaire   +3 more sources

Class A scavenger receptor 1 (MSR1) restricts hepatitis C virus replication by mediating toll-like receptor 3 recognition of viral RNAs produced in neighboring cells

, 2013
Persistent infections with hepatitis C virus (HCV) may result in life-threatening liver disease, including cirrhosis and cancer, and impose an important burden on human health.
McGivern, David R., Fengyu Hu, Daisuke Yamane (206804), David R McGivern, Hu, Fengyu, Hiromichi Dansako (357935), Nobuyuki Kato (235685), Christoph Welsch (22852), Stanley M. Lemon (30543), Daisuke Yamane, Christoph Welsch, Welsch, Christoph, David R. McGivern (415119), Lemon, Stanley M., Kato, Nobuyuki, Fengyu Hu (415120), Dansako, Hiromichi, Stanley M Lemon, Yamane, Daisuke, Nobuyuki Kato, Hiromichi Dansako   +20 more
core   +1 more source

Alzheimer’s Disease, Brain Injury, and C.N.S. Nanotherapy in Humans: Sonoporation Augmenting Drug Targeting

Medical Sciences, 2017
Owing to the complexity of neurodegenerative diseases, multiple cellular types need to be targeted simultaneously in order for a given therapy to demonstrate any major effectiveness.
Joseph S. D’Arrigo
doaj   +1 more source