Advanced glycation end products and their receptors in serum of patients with type 2 diabetes
Glycation is a non-enzymatic process involving the reaction of reducing sugars or reactive oxoaldehyde with proteins, lipids or nucleic acids, which results in the formation of advanced glycation end products (AGEs).
Diana Indyk +3 more
doaj +1 more source
The Past and Present Lives of the Intraocular Transmembrane Protein CD36
Cluster of differentiation 36 (CD36) belongs to the B2 receptors of the scavenger receptor class B family, which is comprised of single-chain secondary transmembrane glycoproteins.
Rucui Yang, Qingping Liu, Mingzhi Zhang
doaj +1 more source
The Helicobacter cinaedi antigen CAIP participates in atherosclerotic inflammation by promoting the differentiation of macrophages in foam cells [PDF]
open12siopenD'Elios, Mario Milco; Vallese, Francesca; Capitani, Nagaja; Benagiano, Marisa; Bernardini, Maria Lina; Rossi, Mirko; Rossi, Gianpaolo; Ferrari, Mauro; Baldari, Cosima Tatiana; Zanotti, Giuseppe; DE BERNARD, Marina; Codolo, GaiaD'Elios, Mario ...
core +1 more source
Roles of reconstituted high-density lipoprotein nanoparticles in cardiovascular disease: A new paradigm for drug discovery [PDF]
Epidemiological results revealed that there is an inverse correlation between high-density lipoprotein (HDL) cholesterol levels and risks of atherosclerotic cardiovascular disease (ASCVD).
Huang, Hui +3 more
core +2 more sources
In addition to its effect on high density lipoprotein (HDL) cholesteryl ester (CE) uptake, scavenger receptor BI (SR-BI) was recently reported to stimulate free cholesterol (FC) flux from Chinese hamster ovary (CHO) cells stably expressing mouse SR-BI, a
Margarita de la Llera-Moya +6 more
doaj +1 more source
Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions [PDF]
The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially ...
Amatruda TT +28 more
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Sterol regulation of scavenger receptor class B type I in macrophages [PDF]
Scavenger receptor class B type I (SR-BI) is expressed in macrophages, but its role in sterol trafficking in these cells remains controversial. We examined the effect of sterol loading on SR-BI expression in human monocytes/macrophages, mouse peritoneal macrophages, and a cultured mouse macrophage cell line (J774 cells).
Liqing Yu +3 more
openaire +3 more sources
Macrophage autophagy in atherosclerosis [PDF]
Macrophages play crucial roles in atherosclerotic immune responses. Recent investigation into macrophage autophagy (AP) in atherosclerosis has demonstrated a novel pathway through which these cells contribute to vascular inflammation.
Carnuccio, R. +5 more
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Targeting SR-BI for cancer diagnostics, imaging and therapy
Scavenger receptor class B type I (SR-BI) plays an important role in trafficking cholesteryl esters between the core of high density lipoprotein and the liver. Interestingly, this integral membrane protein receptor is also implicated in the metabolism of
Maneesha Amrita Rajora +4 more
doaj +1 more source
Targeting Early Dementia: Using Lipid Cubic Phase Nanocarriers to Cross the Blood–Brain Barrier
Over the past decades, a frequent co-morbidity of cerebrovascular pathology and Alzheimer’s disease has been observed. Numerous published studies indicate that the preservation of a healthy cerebrovascular endothelium can be an important therapeutic ...
Joseph S. D’Arrigo
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