Results 11 to 20 of about 51,493 (310)

Scavenger receptor class B type I as a receptor for oxidized low density lipoprotein [PDF]

Journal of Lipid Research, 2001
Scavenger receptor class B type I (SR-BI) has been established as the primary mediator of the selective transfer of lipids from HDL to mammalian cells.
Kristin Gillotte-Taylor, Agnès Boullier, Joseph L. Witztum, Daniel Steinberg, Oswald Quehenberger   +4 more
doaj   +3 more sources

Insights into binding of S100 proteins to scavenger receptors: class B scavenger receptor CD36 binds S100A12 with high affinity. [PDF]

Amino Acids, 2017
The EF-hand type calcium-binding protein S100A12 exerts numerous intra- and extracellular functions of (patho)physiological relevance. Therefore, receptors of S100A12 are of high interest for research and clinical applications. Beside the extensively studied receptor for advanced glycation endproducts (RAGE), G-protein coupled receptors and more ...
Tondera C, Laube M, Pietzsch J.
europepmc   +5 more sources

Scavenger receptor class B type I: a multifunctional receptor [PDF]

Annals of the New York Academy of Sciences, 2011
The scavenger receptor class B type I (SR‐B1) plays an important role in meditating the uptake of HDL‐derived cholesterol and cholesteryl ester in the liver and steroidogenic tissues. In addition to being ubiquitous, SR‐B1 is a high‐density lipoprotein (HDL) receptor in many tissues, though the mechanism by which SR‐B1 does this is unclear.
VALACCHI, Giuseppe, STICOZZI, Claudia, Y. Lim, A. Pecorelli   +3 more
openaire   +3 more sources

Scavenger receptor class B, type 1 facilitates cellular fatty acid uptake [PDF]

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2020
SR-B1 belongs to the class B scavenger receptor, or CD36 super family. SR-B1 and CD36 share an affinity for a wide array of ligands. Although they exhibit similar ligand binding specificity, SR-B1 and CD36 have some very specific lipid transport functions.
Wei, Wang, Zhe, Yan, Jie, Hu, Wen-Jun, Shen, Salman, Azhar, Fredric B, Kraemer   +5 more
openaire   +2 more sources

Dimerization of the scavenger receptor class B type I [PDF]

Journal of Lipid Research, 2004
This study has examined the dimeric/oligomeric forms of scavenger receptor class B type I (SR-BI) and its alternatively spliced form, SR-BII, in a diverse group of cells and tissues: i.e., normal and hormonally altered tissues of mice and rats as well as tissues of transgenic animals and genetically altered steroidogenic and nonsteroidogenic cells ...
Eve Reaven, Yuan Cortez, Susan Leers-Sucheta, Ann Nomoto, Salman Azhar   +4 more
openaire   +2 more sources

MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis.

PLoS Pathogens, 2009
Virtually all of the elements of Mycobacterium tuberculosis (Mtb) pathogenesis, including pro-inflammatory cytokine production, granuloma formation, cachexia, and mortality, can be induced by its predominant cell wall glycolipid, trehalose 6,6 ...
Dawn M E Bowdish, Kaori Sakamoto, Mi-Jeong Kim, Mariliis Kroos, Subhankar Mukhopadhyay, Cynthia A Leifer, Karl Tryggvason, Siamon Gordon, David G Russell   +8 more
doaj   +1 more source

Targeting neuroinflammation in Alzheimer’s disease [PDF]

, 2016
Almost 47 million people suffer from dementia worldwide, with an estimated new case diagnosed every 3.2 seconds. Alzheimer’s disease (AD) accounts for approximately 60%–80% of all dementia cases. Given this evidence, it is clear dementia represents one
Bronzuoli, MARIA ROSANNA, Iacomino, Aniello, Scuderi, Caterina, Steardo, Luca   +3 more
core   +1 more source

Contribution of Glycation and Oxidative Stress to Thyroid Gland Pathology—A Pilot Study

Biomolecules, 2021
The patho-mechanism of changes in the thyroid gland, including carcinogenesis, is a complex process, which involves oxidative stress. The goal of our investigation was to verify the extent of stress in the thyroid gland related to glycation.
Aleksandra Kuzan, Emilia Królewicz, Karolina Nowakowska, Kamilla Stach, Krzysztof Kaliszewski, Paweł Domosławski, Łukasz Kotyra, Andrzej Gamian, Irena Kustrzeba-Wójcicka   +8 more
doaj   +1 more source

Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes. [PDF]

, 2012
BACKGROUND The intricate interactions between the immune, endocrine and central nervous systems shape the innate immune response of the brain. We have previously shown that estradiol suppresses expression of immune genes in the frontal cortex of ...
Carl Cotman, Erik Hrabovszky, Imre Kalló, István Likó, Miklós Sárvári, Nicole Berchtold, Norbert Solymosi, Sárvári, Miklós, Zsolt Liposits   +8 more
core   +2 more sources

Influence of class B scavenger receptors on cholesterol flux across the brush border membrane and intestinal absorption

Journal of Lipid Research, 2009
To learn more about how the step of cholesterol uptake into the brush border membrane (BBM) of enterocytes influences overall cholesterol absorption, we measured cholesterol absorption 4 and 24 h after administration of an intragastric bolus of ...
David V. Nguyen, Victor A. Drover, Martin Knopfel, Padmaja Dhanasekaran, Helmut Hauser, Michael C. Phillips   +5 more
doaj   +1 more source