Results 11 to 20 of about 15,256,107 (329)

Insights into binding of S100 proteins to scavenger receptors: class B scavenger receptor CD36 binds S100A12 with high affinity. [PDF]

open access: yesAmino Acids, 2017
The EF-hand type calcium-binding protein S100A12 exerts numerous intra- and extracellular functions of (patho)physiological relevance. Therefore, receptors of S100A12 are of high interest for research and clinical applications.
Tondera C, Laube M, Pietzsch J.
europepmc   +6 more sources

Regulation of platelet function by class B scavenger receptors in hyperlipidemia [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 2010
Platelets constitutively express class B scavenger receptors CD36 and SR-BI, 2 closely related pattern recognition receptors best known for their roles in lipoprotein and lipid metabolism. The biological role of scavenger receptors in platelets is poorly
A. Zimman, E. Podrez
semanticscholar   +4 more sources

HSL-knockout mouse testis exhibits class B scavenger receptor upregulation and disrupted lipid raft microdomains[S]

open access: yesJournal of Lipid Research, 2012
There is a tight relationship between fertility and changes in cholesterol metabolism during spermatogenesis. In the testis, class B scavenger receptors (SR-B) SR-BI, SR-BII, and LIMP II mediate the selective uptake of cholesterol esters from HDL, which ...
María Emilia Casado   +8 more
doaj   +3 more sources

The Class B Scavenger Receptors SR-BI and CD36 Are Receptors for Anionic Phospholipids (*) [PDF]

open access: yesJournal of Biological Chemistry, 1995
The specific recognition of anionic phospholipids in the outer leaflets of cell membranes and lipoproteins by cell surface receptors may play an important role in a variety of physiologic and pathophysiologic processes (e.g.
A. Rigotti, S. Acton, M. Krieger
semanticscholar   +3 more sources

Distinct mechanisms for OxLDL uptake and cellular trafficking by class B scavenger receptors CD36 and SR-BI

open access: yesJournal of Lipid Research, 2007
Modified forms of LDL, including oxidized low density lipoprotein (OxLDL), contribute to macrophage lipid accumulation in the vessel wall. Despite the pathophysiological importance of uptake pathways for OxLDL, the molecular details of OxLDL endocytosis ...
Bing Sun   +5 more
doaj   +2 more sources

ApoA-II modulates the association of HDL with class B scavenger receptors SR-BI and CD36

open access: yesJournal of Lipid Research, 2004
The class B scavenger receptors SR-BI and CD36 exhibit a broad ligand binding specificity. SR-BI is well characterized as a HDL receptor that mediates selective cholesteryl ester uptake from HDL.
Maria C. de Beer   +5 more
doaj   +2 more sources

Influence of class B scavenger receptors on cholesterol flux across the brush border membrane and intestinal absorption

open access: yesJournal of Lipid Research, 2009
To learn more about how the step of cholesterol uptake into the brush border membrane (BBM) of enterocytes influences overall cholesterol absorption, we measured cholesterol absorption 4 and 24 h after administration of an intragastric bolus of ...
David V. Nguyen   +5 more
doaj   +2 more sources

The class A scavenger receptor SR-A/CD204 and the class B scavenger receptor CD36 regulate immune functions of macrophages differently [PDF]

open access: yesInnate Immunity, 2014
SR-A/CD204 and CD36 are major receptors responsible for oxidized lipoproteins uptake by macrophages in atherosclerotic plaques. Both receptors also share the role as receptors for different pathogens, but studies on their signaling have been hampered by the lack of selective ligands. We report that, upon specific ligation by Ab, SR-
S. Jozefowski   +4 more
semanticscholar   +4 more sources

Scavenger receptor class B type I as a receptor for oxidized low density lipoprotein [PDF]

open access: yesJournal of Lipid Research, 2001
Scavenger receptor class B type I (SR-BI) has been established as the primary mediator of the selective transfer of lipids from HDL to mammalian cells.
Kristin Gillotte-Taylor   +4 more
doaj   +3 more sources

Structural Basis for the Recognition of Oxidized Phospholipids in Oxidized Low Density Lipoproteins by Class B Scavenger Receptors CD36 and SR-BI*

open access: yesJournal of Biological Chemistry, 2009
Specific oxidized phospholipids (oxPCCD36) accumulate in vivo at sites of oxidative stress and serve as high affinity ligands for scavenger receptors class B (CD36 and SR-BI).
Detao Gao   +5 more
semanticscholar   +2 more sources

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