Results 31 to 40 of about 24,292 (301)

Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors

, 2010
Hepatitis C virus (HCV) naturally infects only humans and chimpanzees. The determinants responsible for this narrow species tropism are not well defined.
Christiane Brohm, Kathrin Hueging, Michael Ott, Hueging, Kathrin, Brohm, Christiane, Ott, Michael, Bitzegeio, Julia, Dorothea Bankwitz, Herrmann, Eva, Sibylle Haid, Thomas Pietschmann, Mirjam B. Zeisel, Baumert, Thomas F, Iken, Marcus, Haid, Sibylle, Marcus Iken, Julia Bitzegeio, Thomas F. Baumert, Zeisel, Mirjam B, Thomas F Baumert, Mirjam B Zeisel, Eva Herrmann, Baumert, Thomas, Bankwitz, Dorothea, Zeisel, Mirjam B., Pietschmann, Thomas   +25 more
core   +1 more source

CD36 does not play a direct role in HDL or LDL metabolism

Journal of Lipid Research, 2001
CD36 and scavenger receptor class B, type I (SR-BI) are both class B scavenger receptors that recognize a broad variety of ligands, including oxidized low density lipoprotein (oxLDL), HDL, anionic phospholipids, and apoptotic cells.
Willem J.S. de Villiers, Lei Cai, Nancy R. Webb, Maria C. de Beer, Deneys R. van der Westhuyzen, Frederick C. de Beer   +5 more
doaj   +1 more source

Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus. [PDF]

PLoS Pathogens, 2016
Scavenger receptor class B type 1 (SR-B1) and low-density lipoprotein receptor (LDLR) are known to be involved in entry of hepatitis C virus (HCV), but their precise roles and their interplay are not fully understood. In this study, deficiency of both SR-
Satomi Yamamoto, Takasuke Fukuhara, Chikako Ono, Kentaro Uemura, Yukako Kawachi, Mai Shiokawa, Hiroyuki Mori, Masami Wada, Ryoichi Shima, Toru Okamoto, Nobuhiko Hiraga, Ryosuke Suzuki, Kazuaki Chayama, Takaji Wakita, Yoshiharu Matsuura   +14 more
doaj   +1 more source

Developmental and Hormonal Regulation of Murine Scavenger Receptor, Class B, Type 1 [PDF]

Molecular Endocrinology, 1999
The scavenger receptor, class B, type I (SR-BI), is the predominant receptor that supplies plasma cholesterol to steroidogenic tissues in rodents. We showed previously that steroidogenic factor-1 (SF-1) binds a sequence in the human SR-BI promoter whose integrity is required for high-level SR-BI expression in cultured adrenocortical tumor cells. We now
G, Cao, L, Zhao, H, Stangl, T, Hasegawa, J A, Richardson, K L, Parker, H H, Hobbs   +6 more
openaire   +2 more sources

Quantification of apolipoprotein E receptors in human brain-derived cell lines by real-time polymerase chain reaction

, 2004
Apolipoprotein (apo) E4 is a risk factor for Alzheimer's disease (AD) and other neurodegenerative diseases, compared to wild-type apoE3. The mechanism(s) is unknown.
Owen, JS, Everett, D M, Murdock, P R, Everett, DM, Murdock, PR, Owen, J S, Dingwall, C, Thilakawardhana, S   +7 more
core   +1 more source

Myricetin ameliorates atherosclerosis in the low-density-lipoprotein receptor knockout mice by suppression of cholesterol accumulation in macrophage foam cells

Nutrition & Metabolism, 2019
Background Myricetin, a major flavonoid found in several foods including berries, grapes and wine, exhibited strong antioxidant potency, yet the effect on atherosclerosis is not fully understood.
Zhe Meng, Mengyu Wang, Junhui Xing, Yuzhou Liu, Haiyu Li   +4 more
doaj   +1 more source

β-Amyloid promotes accumulation of lipid peroxides by inhibiting CD36-mediated clearance of oxidized lipoproteins

Journal of Neuroinflammation, 2004
Background Recent studies suggest that hypercholesterolemia, an established risk factor for atherosclerosis, is also a risk factor for Alzheimer's disease.
Khan Tayeba, Medeiros Lea A, Tseng Anita A, Kunjathoor Vidya V, Moore Kathryn J   +4 more
doaj   +1 more source

Biomimetic Nanocarrier Targeting Drug(s) to Upstream-Receptor Mechanisms in Dementia: Focusing on Linking Pathogenic Cascades

Biomimetics, 2020
Past published studies have already documented that, subsequent to the intravenous injection of colloidal lipid nanocarriers, apolipoprotein (apo)A-I is adsorbed from the blood onto the nanoparticle surface.
Joseph S. D’Arrigo
doaj   +1 more source

Scavenger Receptor Class B Type I Is a Plasma Membrane Cholesterol Sensor [PDF]

Circulation Research, 2013
Rationale: Signal initiation by the high-density lipoprotein (HDL) receptor scavenger receptor class B, type I (SR-BI), which is important to actions of HDL on endothelium and other processes, requires cholesterol efflux and the C-terminal transmembrane domain.
Sonika, Saddar, Véronique, Carriere, Wan-Ru, Lee, Keiji, Tanigaki, Ivan S, Yuhanna, Sajesh, Parathath, Etienne, Morel, Manya, Warrier, Janet K, Sawyer, Robert D, Gerard, Ryan E, Temel, J Mark, Brown, Margery, Connelly, Chieko, Mineo, Philip W, Shaul   +14 more
openaire   +2 more sources

Contribution of receptors to 'Neisseria meningitidis' interactions with human macrophages [PDF]

, 2004
N. meningitidis is a gram-negative human pathogen that invades human cells, evades immune responses and goes on to cause meningococcal disease, sepsis and death.
Abdillahi, Fatumo Abdi
core