Results 41 to 50 of about 1,272,764 (261)

Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors [PDF]

open access: yes, 2010
Hepatitis C virus (HCV) naturally infects only humans and chimpanzees. The determinants responsible for this narrow species tropism are not well defined.
Christiane Brohm   +25 more
core   +2 more sources

Scavenger receptor-BI is a receptor for lipoprotein(a)

open access: yesJournal of Lipid Research, 2013
Scavenger receptor class B type I (SR-BI) is a multi-ligand receptor that binds a variety of lipoproteins, including high density lipoprotein (HDL) and low density lipoprotein (LDL), but lipoprotein(a) [Lp(a)] has not been investigated as a possible ...
Xiao-Ping Yang   +9 more
doaj   +1 more source

Ontogeny, immunolocalisation, distribution and function of SR-BI in the human intestine [PDF]

open access: yesJournal of Cell Science, 2004
Studies employing human fetal intestine have yielded remarkable information on the role of polarized enterocytes in fat absorption. In this report, we investigated the intestinal expression, spatiotemporal distributions, ontogeny and function of the scavenger receptor, Class B, Type I (SR-BI) that plays a crucial role in cholesterol homeostasis.
Emile, Levy   +7 more
openaire   +2 more sources

The role of scavenger receptor B-I in hepatitis C virus attachment and entry. [PDF]

open access: yes, 2009
Hepatitis C Virus (HCV) poses a global health problem, leading to progressive disease often culminating in conditions such as hepatocellular carcinoma.
Grove, Joseph
core   +7 more sources

Scavenger receptor class B type I reduces cholesterol absorption in cultured enterocyte CaCo-2 cells1

open access: yesJournal of Lipid Research, 2004
Scavenger receptor class B type I (SR-BI) mediates selective uptake of cholesteryl esters from HDL as well as efflux of cellular free cholesterol to HDL. It is unclear whether the receptor is involved in intestinal cholesterol absorption.
Lei Cai   +6 more
doaj   +1 more source

The predominance of one of the SR-BI isoforms is associated with increased esterified cholesterol levels not apoptosis in mink testis

open access: yesJournal of Lipid Research, 2006
Scavenger receptor class B type I (SR-BI) contributes to HDL-mediated cellular cholesterol efflux and is a phagocytosis-inducing phospholipid phosphatidylserine receptor in rat Sertoli cells, whereas the spliced variant of the SR-B gene, SR-BII, is ...
Casimir D. Akpovi   +3 more
doaj   +1 more source

Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type I-deficient mice

open access: yesJournal of Lipid Research, 2001
The scavenger receptor class B type I (SR-BI), which is expressed in the liver and intestine, plays a critical role in cholesterol metabolism in rodents.
Pablo Mardones   +11 more
doaj   +1 more source

Studies of SR-BI in HDL Lipid Uptake in Hepatocytes [PDF]

open access: yes, 2007
Gene-targeted studies in mice have shown that the murine scavenger receptor class B type I (mSR-BI) is atheroprotective and plays a key role in the clearance of high density lipoprotein (HDL) cholesterol by the liver. We focused on the analysis of human
Brunet, Rachelle
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Regulation of scavenger receptor class B type I in hamster liver and Hep3B cells by endotoxin and cytokines

open access: yesJournal of Lipid Research, 2001
Multiple changes in HDL metabolism occur during infection and inflammation that could potentially impair the antiatherogenic functions of HDL. Scavenger receptor class B type I (SR-BI) promotes cholesterol efflux from peripheral cells and mediates ...
Weerapan Khovidhunkit   +4 more
doaj   +1 more source

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