Results 21 to 30 of about 895,142 (270)

Macrophage SR-BI regulates LPS-induced pro-inflammatory signaling in mice and isolated macrophages

Journal of Lipid Research, 2012
Scavenger receptor BI (SR-BI), an HDL receptor, plays a key role in reverse cholesterol transport. In mice, disruption of SR-BI results in hypersensitivity to lipopolysaccharide (LPS) and bacteria-induced septic shock due to adrenal insufficiency and ...
Lei Cai, Zhen Wang, Jason M. Meyer, Ailing Ji, Deneys R. van der Westhuyzen   +4 more
doaj   +1 more source

Scavenger receptor BI facilitates the metabolism of VLDL lipoproteins in vivo

Journal of Lipid Research, 2008
Scavenger receptor class B type I (SR-BI) functions as an HDL receptor that promotes the selective uptake of cholesteryl esters (CEs). The physiological role of SR-BI in VLDL metabolism, however, is largely unknown.
Miranda Van Eck, Menno Hoekstra, Ruud Out, I. Sophie T. Bos, J. Kar Kruijt, Reeni B. Hildebrand, Theo J.C. Van Berkel   +6 more
doaj   +1 more source

Scavenger receptor SR-BI in macrophage lipid metabolism [PDF]

Atherosclerosis, 2011
To investigate the mechanisms by which macrophage scavenger receptor BI (SR-BI) regulates macrophage cholesterol homeostasis and protects against atherosclerosis.The expression and function of SR-BI was investigated in cultured mouse bone marrow-derived macrophages (BMM).
Ailing, Ji, Jason M, Meyer, Lei, Cai, Akinwunmi, Akinmusire, Maria C, de Beer, Nancy R, Webb, Deneys R, van der Westhuyzen   +6 more
openaire   +2 more sources

SR-BI Selective Lipid Uptake [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2009
Objective— The purpose of this study was to investigate the interaction of SAA and SR-BI in remodeling of acute phase HDL (AP HDL). Methods and Results— We used SAA and SR-BI adenoviral vector expression models to study the ...
Maria C, de Beer, Nancy R, Webb, Nathan L, Whitaker, Joanne M, Wroblewski, Anisa, Jahangiri, Deneys R, van der Westhuyzen, Frederick C, de Beer   +6 more
openaire   +2 more sources

17β-Estradiol promotes the up-regulation of SR-BII in HepG2 cells and in rat livers

Journal of Lipid Research, 2001
The scavenger receptor class B type I (SR-BI) binds to HDL and mediates the selective uptake of cholesterol esters from HDL to cells. SR-BII is an alternatively spliced product of the SR-BI gene that only differs in the C-terminal cytoplasmic domain ...
Gregory A. Graf, Kathy L. Roswell, Eric J. Smart   +2 more
doaj   +1 more source

Influence of the HDL Receptor SR-BI on Lipoprotein Metabolism and Atherosclerosis [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2003
The scavenger receptor class B type I (SR-BI) was the first molecularly well-defined cell-surface HDL receptor to be described. SR-BI mediates selective HDL cholesterol uptake by formation of a productive lipoprotein/receptor complex, which requires specific structural domains and conformation states of apolipoprotein A-I present in HDL particles.
Trigatti, BL, Krieger, M, Rigotti, A
openaire   +4 more sources

Differentiation-dependent expression and localization of the class B type I scavenger receptor in intestine

Journal of Lipid Research, 2001
The current study used the human Caco-2 cell line and mouse intestine to explore the topology of expression of the class B type I scavenger receptor (SR-BI) in intestinal cells.
Sheng F. Cai, R. Jason Kirby, Philip N. Howles, David Y. Hui   +3 more
doaj   +1 more source

Human variant of scavenger receptor BI (R174C) exhibits impaired cholesterol transport functions

Journal of Lipid Research, 2021
: HDL and its primary receptor, scavenger receptor class B type I (SR-BI), work together to promote the clearance of excess plasma cholesterol, thereby protecting against atherosclerosis. Human variants of SR-BI have been identified in patients with high
Sarah C. May, Jacqueline S. Dron, Robert A. Hegele, Daisy Sahoo   +3 more
doaj   +1 more source

Diffusion of Sr, Bi, and Ta in amorphous SiO2 [PDF]

Materials Science in Semiconductor Processing, 2003
Abstract Diffusion of Sr, Bi, and Ta in SiO2 was studied to determine diffusion coefficients and diffusion mechanisms of these elements in the amorphous material. Technological motivation is the introduction of strontium bismuth tantalate (SBT) as ferroelectric material for nonvolatile memories.
Ralf Büngener, Werner Pamler, Ulrich Gösele   +2 more
openaire   +1 more source

Hvordan få til sirkulær massehåndtering for bygg- og anleggsprosjekter i Oslo-området? [PDF]

, 2021
Dette forprosjektet har hatt som formål å identifisere interessante aspekter og problemstillinger knyttet til spørsmålet: Hvordan kan man få til sirkulær massehåndtering til og fra bygg- og anleggsprosjekter i Oslo-området? For å svare på spørsmålet, har
Bygballe, Lena Elisabeth, Harrison, Debbie, Flygansvær, Bente Merete, Soldal, Olav B.   +3 more
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