Animal Research and One Health, EarlyView.This study was to evaluate the role of GH in lipolysis and insulin sensitivity in bovine adipocytes and clarify the underlying mechanism. Our findings demonstrate that GH activates ERK/HSL signaling pathway, promotes lipolysis, and impairs insulin sensitivity in bovine adipocytes.
Xinxing Gao +10 more
wiley +1 more source
Integrating Transcriptomics and Gut Microbiota Analysis Reveals the Anti-Osteoporotic Mechanisms of Wine and Oil Co-Processed Epimedium. [PDF]
FASEB JLiang J +9 more
europepmc +1 more source
Metastasis-suppressor KAI1/CD82 induces homotypic aggregation of human prostate cancer cells through Src-dependent pathway [PDF]
, 2003 Bokeun Jee +4 more
openalex +1 more source
Prothrombotic Activation of Platelet Pannexin 1 Channels in Antiphospholipid Syndrome
Arthritis &Rheumatology, Accepted Article.Background ATP is released from platelets through both degranulation and pannexin‐1 (PANX1) channels. ATP then activates P2X receptors to amplify platelet activation via calcium‐dependent signaling. Objective To evaluate the role of platelet PANX1 channels in the pathophysiology of antiphospholipid syndrome (APS), an acquired thrombo‐inflammatory ...
Bruna de Moraes Mazetto Fonseca +13 more
wiley +1 more source
Computational Insights into the Molecular Mechanisms of <i>Coptis chinensis</i> Franch. in Treating Chronic Atrophic Gastritis: An Integrated Network Pharmacology, Machine Learning, and Molecular Dynamics Study. [PDF]
Int J Mol SciHu C, Liu Y, Ding Y, Jin Y, Han W.
europepmc +1 more source
Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases
BMEMat, EarlyView.This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou +6 more
wiley +1 more source
Unraveling the mechanisms of nicotine-induced osteoporosis via network toxicology, bioinformatics, and molecular docking. [PDF]
Tob Induc DisXu S +6 more
europepmc +1 more source
Business Strategy and the Environment, EarlyView.ABSTRACT This paper contributes to venture‐creation research by examining how sustainable startups can overcome market constraints to drive transformative change through their business development. Conceptually, we address this question by identifying venture‐creation narratives in the learning and experimental phases of sustainable startups that ...
Ville‐Veikko Piispanen +2 more
wiley +1 more source
Sport-related Concussion Can be Prevented by Injury Prevention Program: A Systematic Review and Meta-analysis of Prospective, Controlled Studies. [PDF]
Sports Med OpenChen YL, Chou TY, Sung MC, Huang YL.
europepmc +1 more source