Results 171 to 180 of about 153,822 (251)

Correction: Taletrectinib promotes pyroptosis in colorectal carcinoma via SRC/AKT/mTOR axis inhibition. [PDF]

Sci Rep
Zhang T, Zou Y, Zhang SH, Wang YY, He S, Yuan W, Yang M, Liu T, Deng SH, Wu DM, Xu Y.   +10 more
europepmc   +1 more source

Hsp90 Inhibition on the Western Blot: N‐Terminal Versus C‐Terminal Inhibitors in Breast Cancer

Medicinal Research Reviews, EarlyView.
ABSTRACT Heat shock protein 90 (Hsp90) is an established and clinically validated anticancer target. By regulating the folding and maturation of diverse client proteins, it is indirectly involved in carcinogenesis. Key breast cancer oncogenic drivers, including estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, are ...
Jaka Dernovšek, Jernej Cingl, Urša Pečar Fonović, Tihomir Tomašič   +3 more
wiley   +1 more source

uPAR/suPAR Signaling and Organ Crosstalk in Cardiovascular-Kidney-Metabolic Syndrome. [PDF]

Circ Res
Hayek SS, Dryer SE.
europepmc   +1 more source

Muscle‐Specific Kinase Signaling and Its Therapeutic Potential

Muscle &Nerve, EarlyView.
ABSTRACT The function of the neuromuscular junction (NMJ) is compromised in many neuromuscular diseases (NMDs) such as autoimmune or congenital myasthenia gravis (MG), amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA), and muscular dystrophies.
Stine Marie Jensen, Dana L. E. Vergoossen, Maartje G. Huijbers   +2 more
wiley   +1 more source

Association of Glucagon‐Like Peptide‐1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes

Obesity, EarlyView.
ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu, Hao Dai, Huilin Tang, William T. Donahoo, Thomas J. George, Ramon C. Sun, Sizun Jiang, Aik Choon Tan, Yi Guo, Jonathan D. Licht, John M. Allen, Kelvin P. Lee, Jingchuan Guo, Jiang Bian   +13 more
wiley   +1 more source

Metacognitive monitoring and calibration in the vocal emotion recognition task. [PDF]

Front Psychol
Sinvani RT, Fogel-Grinvald H.
europepmc   +1 more source

Multi-omics integration and experimental validation reveal the mechanism of berberine against triple-negative breast cancer. [PDF]

Front Pharmacol
Zhang Y, Lu T, Liu K, Zhang B, Xu S.
europepmc   +1 more source

Unpacking the task of synthesis when weaving knowledge systems for biodiversity assessments

People and Nature, EarlyView.
Abstract The pivot towards evidence‐based conservation since 2000 has inspired global environmental assessments to gather evidence across multiple knowledge systems, including through co‐production with Indigenous Peoples and local communities. Knowledge co‐production is highlighted as a strategy for transformative change towards a just future that ...
Maria Tengö, Isabel Díaz‐Reviriego, Álvaro Fernández‐Llamazares, Pernilla Malmer, Wilfredo V. Alangui, Puaʻala Pascua, Prasert Trakansuphakon, Rosemary Hill   +7 more
wiley   +1 more source

Directly adopting inverse biosensors to image live cell enzyme activities in nanodomains. [PDF]

Proc Natl Acad Sci U S A
Srivastava K, Schnur KP, Petruzzi K, Mo GCH.   +3 more
europepmc   +1 more source