Results 191 to 200 of about 153,822 (251)

Hybrid physics–data‐driven modeling for sea ice thermodynamics and transfer learning

Quarterly Journal of the Royal Meteorological Society, EarlyView.
Icepack–NN, a machine‐learning‐based hybrid version of the sea‐ice column model Icepack, is developed to correct state‐dependent forecast errors arising from misspecified snow thermodynamics, using neural networks applied online within the physical model.
G. De Cillis, A. Carrassi, J. Brajard, L. Bertino, M. Broccoli, D. Iovino, T.S. Finn, M. Bocquet   +7 more
wiley   +1 more source

How are gender and sexual minority populations included in climate change-associated disaster preparedness plans in Bulawayo Province? A mixed-methods research protocol. [PDF]

BMJ Public Health
Ncube O, Khozah MY, Nunu WN.
europepmc   +1 more source

Stair‐Climbing Wheelchairs for Enhanced Mobility: A Comprehensive Review of Fundamental Mechanisms, Design Concepts, and Performance Analysis

Journal of Field Robotics, EarlyView.
ABSTRACT People with physical disabilities face significant mobility challenges while climbing uneven surfaces and staircases. In these circumstances, traditional wheelchairs do not provide stable, safely controlled mobility, underscoring the importance of building superior stair‐climbing wheelchairs for both medical and infrastructure purposes.
Gopisetti Manikanta, S. M. Abhinandan, Anand Reddy, G. Chandana, Divya, P. Anil Kumar, Ch. Venkata Rao, Ashish Garg, Ravi C. Soni, Jogendra Kumar, Bhargav Akkinepally   +10 more
wiley   +1 more source

Selective antitumor and apoptosis‑inducing effects of the Src inhibitor PP1 in human tongue squamous cell carcinoma cells. [PDF]

Int J Oncol
Kantibekovna SL, Wang S, Kang H, Shin YM, Jang BC.   +4 more
europepmc   +1 more source

MXene Bioinks for 3D Bioprinting: Design and Translation

Small, EarlyView.
This study establishes a comprehensive framework for MXene‐based bioinks in 3D bioprinting, highlighting the interplay between rheological engineering and electroactive hydrogels. By optimizing electrical percolation and mediated signaling, these formulations drive tissue‐specific biological outcomes and accelerated regeneration.
Begüm Sarac, Seydanur Yücer, Fatih Ciftci   +2 more
wiley   +1 more source

Assessing Lymph Node Metastasis Risk in Patients With Mucosal Gastric Cancer: A Comparison of the WHO and Japanese Criteria and Implications for Endoscopic Submucosal Dissection. [PDF]

JGH Open
Kim JC, Cho YS, Kwak Y, Kong SH, Park DJ, Cho SJ, Lee HJ, Lee HS, Yang HK.   +8 more
europepmc   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

SRC-mediated phosphorylation of UBC9 regulates inflammatory and metabolic signaling in alcohol-associated liver disease. [PDF]

Sci Adv
Chandla S, Lim Y, Floris A, Mazarei M, Yang X, Tsuchiya T, Dagar M, Darmawan A, Justo M, Murali R, Gangi A, Tomasi I, Mavila N, Ramani K, Tomasi ML.   +14 more
europepmc   +1 more source

The Complement System in Post‐Transplant Kidney Injury

Organ Medicine, EarlyView.
Mengsi Hu
wiley   +1 more source

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

Smart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang, Haitao Xie, Guoqing Xiang, Yanhua Li, Changgui Tong, Hongyan Cui, Qixian Chen, Haidong Li, Yan Zhao   +8 more
wiley   +1 more source