Results 211 to 220 of about 260,978 (272)

A case of invasive lobular carcinoma with signet-ring-cell differentiation treated with multidisciplinary therapy: a rare case report. [PDF]

Front Oncol
Takuwa H, Hori T, Goda N, Takeuchi M.
europepmc   +1 more source

Hsp90 Inhibition on the Western Blot: N‐Terminal Versus C‐Terminal Inhibitors in Breast Cancer

Medicinal Research Reviews, EarlyView.
ABSTRACT Heat shock protein 90 (Hsp90) is an established and clinically validated anticancer target. By regulating the folding and maturation of diverse client proteins, it is indirectly involved in carcinogenesis. Key breast cancer oncogenic drivers, including estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, are ...
Jaka Dernovšek, Jernej Cingl, Urša Pečar Fonović, Tihomir Tomašič   +3 more
wiley   +1 more source

Curcumol Alleviates Obesity-Related Insulin Resistance and Inflammation in Skeletal Muscle via the SRC/PI3K/AKT Axis. [PDF]

Nutrients
Fu Y, Zeng X, Zhou B, Wang J, Qin H.
europepmc   +1 more source

Fast Reconstruction of Motion‐Corrupted Data With Mobile‐GRAPPA: Motion and δB0$$ \delta {B}_0 $$ Inhomogeneity Correction Leveraging Efficient GRAPPA

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop an accurate and computationally efficient motion‐corrected MRI reconstruction framework that incorporates hundreds to thousands of motion and δB0$$ \delta {B}_0 $$ estimates from high‐temporal‐resolution tracking. Methods We propose Mobile‐GRAPPA, a k‐space preprocessing approach that uses MLP‐parameterized local GRAPPA ...
Yimeng Lin, Nan Wang, Daniel Abraham, Daniel Polak, Xiaozhi Cao, Aizada Nurdinova, Stephen Cauley, Kawin Setsompop   +7 more
wiley   +1 more source

Integrated Network Pharmacology and Molecular Dynamics Reveal Luteolin from <i>Persea americana</i> as a Multi-Cancer SRC/GSK3β Inhibitor. [PDF]

Int J Mol Sci
Swaroop AK, Sanapalli BKR, Selvaraj J, Sigalapalli DK, Tokala R, Sanapalli V.   +5 more
europepmc   +1 more source

UNC5B regulates epithelial-to-mesenchymal transition through a SRC-ZEB1 signaling axis to facilitate pancreatic cancer metastasis. [PDF]

Oncogene
Sadeqi Nezhad M, Harris CR, Prela O, Narrow W, Breitenbach M, Wang L, Jain S, Becker JL, Bagci B, Hao Y, Hezel AF, Gerber SA, Mello S, Withers T, Carpizo DR.   +14 more
europepmc   +1 more source

Unpacking the task of synthesis when weaving knowledge systems for biodiversity assessments

People and Nature, EarlyView.
Abstract The pivot towards evidence‐based conservation since 2000 has inspired global environmental assessments to gather evidence across multiple knowledge systems, including through co‐production with Indigenous Peoples and local communities. Knowledge co‐production is highlighted as a strategy for transformative change towards a just future that ...
Maria Tengö, Isabel Díaz‐Reviriego, Álvaro Fernández‐Llamazares, Pernilla Malmer, Wilfredo V. Alangui, Puaʻala Pascua, Prasert Trakansuphakon, Rosemary Hill   +7 more
wiley   +1 more source

Cross‐Platform Comparison of Chemoproteomics Workflows: Orbitrap‐TMT Versus timsTOF‐diaPASEF

PROTEOMICS, EarlyView.
ABSTRACT Chemoproteomics aims to achieve precise and comprehensive quantification of protein–small molecule interactions, yet methodological comparisons across quantitative proteomics workflows remain scarce. Here, we systematically benchmark tandem mass tag data‐dependent acquisition (TMT‐DDA) on Orbitrap Exploris/Eclipse instruments against label ...
Ursula M. Glocker, Michael Steidel, Henrik Hammarén, Carola Doce, Katrin Marcus, Nico Zinn, Marcus Bantscheff, H. Christian Eberl   +7 more
wiley   +1 more source

N-Myristoyltransferase 2 Is Regulated by Polyphosphate-Driven Lysine Interactions. [PDF]

Biomolecules
Martins I, Bailey K, Ge A, Belrose E, Yang X, Jia Z.   +5 more
europepmc   +1 more source

Aboveground herbivory elevates belowground rhizosphere volatile organic compound concentrations in ambient and polluted air, independent of volatile sampling methodology

PLANTS, PEOPLE, PLANET, EarlyView.
The effect of air pollution on plants is still underexplored, especially belowground. We used a field facility that released diesel exhaust and ozone at concentrations equivalent to those near a busy road in Reading, UK, to measure belowground gas exchange of Scots pine together with feeding by large pine weevils, a major pest of conifers.
Tihomir Simin, Luke Bell, James M. W. Ryalls, Robbie D. Girling, Oliver E. I. Welling, Neil J. Mullinger, Muhammad Usman Rasheed, James D. Blande   +7 more
wiley   +1 more source