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Targeting SRC kinase (SRC) in melanoma cells.
Journal of Clinical Oncology, 20108584 Background: The SRC family of tyrosine kinases have been implicated in melanoma progression.
A. J. Eustace +8 more
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Nature, 1994
The activity of the c-Src protein is increased during cell-cycle stage G1 in fibroblasts stimulated with certain growth factors, and at the G2/M transition, but little is known about Src substrates in these circumstances. In contrast, cells transformed with activated Src contain many tyrosine-phosphorylated proteins.
S, Fumagalli +3 more
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The activity of the c-Src protein is increased during cell-cycle stage G1 in fibroblasts stimulated with certain growth factors, and at the G2/M transition, but little is known about Src substrates in these circumstances. In contrast, cells transformed with activated Src contain many tyrosine-phosphorylated proteins.
S, Fumagalli +3 more
openaire +2 more sources
Src activation in melanoma and Src inhibitors as therapeutic agents in melanoma
Melanoma Research, 2009Src signaling has been implicated in several malignancies including melanoma. The prevalence of Src activation in human melanoma and the effect of the newer Src inhibitors, dasatinib, and bosutinib (SKI-606), as single agents or in combination, on melanoma cell lines is not well established.
Jade, Homsi +8 more
openaire +2 more sources
Targeted Degradation of Transcription Coactivator SRC‐1 through the N‐Degron Pathway
Angewandte Chemie - International Edition, 2020Hyun Kyu Song, G-One Ahn, Do Hoon Kwon
exaly
Selected glimpses into the activation and function of Src kinase
Oncogene, 2000Donald J Fujita +2 more
exaly
Src in cancer: deregulation and consequences for cell behaviour
Biochimica Et Biophysica Acta: Reviews on Cancer, 2002Margaret Frame
exaly