Results 221 to 230 of about 260,978 (272)

Baicalin Induces Ferroptosis in Breast Cancer Through a Novel STAT3/HO‐1/GPX4 Regulatory Axis

Phytotherapy Research, EarlyView.
BA inhibits STAT3 phosphorylation and activation in BC cells, accompanied by decreased expression of HO‐1 and GPX4. Reduced GPX4 activity impairs lipid peroxide clearance, promoting ROS accumulation and lipid peroxidation, which ultimately triggers ferroptosis and inhibits cell proliferation.
Tingting Guo, Fansu Meng, Detang Li, Maciej Mazur, Alicia Marcelina Díaz García, Mulazim Hussain Asim, Zhong Chen, Yiqi Chen, Yixuan Lin, Zhenjiang Yang, Panpan Wang, Yu Cai   +11 more
wiley   +1 more source

Salvianolic Acid A Induces Ferroptosis in Non-Small Cell Lung Cancer via the SRC/YAP/GPX4 Axis. [PDF]

Int J Mol Sci
Jiang R, Liu H, Xiang H, Tang X, Zhao L, Zeng D, Zhang Y, Xie J, Gong Y, Yang L.   +9 more
europepmc   +1 more source

Integrative Approaches in Cardiovascular Disease: The Role of Nutraceuticals in Heart Failure, Atrial Fibrillation, and Related Conditions

Phytotherapy Research, EarlyView.
Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli, Ivan Corazza, Roberta Budriesi, Luca Camarda, Maria Carelli, Alberto Spadotto, Igor Diemberger   +6 more
wiley   +1 more source

Damage recognition by intestinal stem cells via Draper promotes adult Drosophila midgut regeneration. [PDF]

EMBO J
Legido M, Srotyr M, Wafer R, Patel PH.
europepmc   +1 more source

Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine

Phytotherapy Research, EarlyView.
By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao, Huiming Huang, Xuejiao Wei, Xiaoxue Wang, Wanying Xie, Xinyu Qiu, Fei Wang, Zhuguo Wang, Ruoxin Zhang, Yilin Cai, Changhai Qu, Zhongdong Hu   +11 more
wiley   +1 more source

Using reference intervals to improve interpretation of youth sport-related concussion biomarkers using a research platform. [PDF]

Brain Commun
Achalu K, Cooper JG, Tabor JB, Ghodsi M, Huang J, Josafatow-García N, Penner LC, Stukas S, Galarneau JM, Fraser DD, Smirl J, Yeates KO, Debert CT, Emery CA, Wellington CL.   +14 more
europepmc   +1 more source

Stair‐Climbing Wheelchairs for Enhanced Mobility: A Comprehensive Review of Fundamental Mechanisms, Design Concepts, and Performance Analysis

Journal of Field Robotics, EarlyView.
ABSTRACT People with physical disabilities face significant mobility challenges while climbing uneven surfaces and staircases. In these circumstances, traditional wheelchairs do not provide stable, safely controlled mobility, underscoring the importance of building superior stair‐climbing wheelchairs for both medical and infrastructure purposes.
Gopisetti Manikanta, S. M. Abhinandan, Anand Reddy, G. Chandana, Divya, P. Anil Kumar, Ch. Venkata Rao, Ashish Garg, Ravi C. Soni, Jogendra Kumar, Bhargav Akkinepally   +10 more
wiley   +1 more source

Quantitative bias analyses to address measurement error in time-to-event endpoints. [PDF]

Am J Epidemiol
Ackerman B, Gan RW, Zhang Y, Hayden J, Wang JR, Meyer CS, Siddique J, Lund JL, Weberpals J, Schneeweiss S, Stürmer T, Roose J, Nadeem O, Raje N, Ailawadhi S, Giri S, Hester L, Brayer J, Batavia AS.   +18 more
europepmc   +1 more source

Generative AI‐Driven Supply Chain Digital Innovation: Enabling Integration, Resilience, and Sustainable Business Value Creation

Sustainable Development, EarlyView.
ABSTRACT In today's volatile, uncertain, complex, and ambiguous (VUCA) business environment, organizations face mounting pressure to develop agile and resilient supply chains capable of withstanding increasingly frequent disruptions. At the same time, sustainability has evolved into a strategic necessity, requiring firms to balance competitiveness with
Arsalan Zahid Piprani, Sajid Nazir, Mahmood Ali, Sumona Mukhuty, Jyri Vilko   +4 more
wiley   +1 more source

World Models for Robotic Manipulation: A Survey

SmartBot, EarlyView.
World models enable robots to anticipate how candidate actions may alter object configurations, contact states, and scene geometry before physical execution. This survey examines world models for robotic manipulation as action‐conditioned predictive systems and organizes the literature according to predicted representations, interfaces between ...
Fangyuan Wang, Ziyuan Wang, Guorui Pei, Mengshi Zhang, Canxi Liang, Jun Hu, Zhongxuan Li, Jinsong Wu, Ning Han, Zeqing Zhang, Jiaming Qi, Hongmin Wu, Shiyao Zhang, Pai Zheng, Jia Pan, David Navarro‐Alarcon, Sichao Liu, Peng Zhou   +17 more
wiley   +1 more source