Results 161 to 170 of about 242,192 (301)
Depression accelerates tumor growth by dysregulation of tumor immune microenvironment. (A) Modeling methods: Subcutaneous tumor models were established under chronic unpredictable mild stress conditions, including cold swimming, physical restraint, and food/water deprivation, leading to increased tumor growth.
Yakun Ren +6 more
wiley +1 more source
Objective Dermal systemic sclerosis (SSc) fibroblasts and their exosomes can activate keratinocytes in SSc, with long noncoding RNA (lncRNA) H19 highlighted as the most up‐regulated RNA in their cargo compared with healthy controls (HCs). The role of H19 in SSc pathogenesis has never been investigated.
Begoña Caballero‐Ruiz +3 more
wiley +1 more source
Objective Members of the superfamily of nuclear receptors have been implicated in inflammatory processes and pathologic tissue remodeling and have emerged as attractive targets for pharmaceutical intervention. However, the role of testicular receptor 4 (TR4; or Nr2c2) in fibroblast activation and rheumatologic diseases has not yet been investigated ...
Yun Zhang +16 more
wiley +1 more source
Inhibition of SRC prevents bone metastasis of breast cancer by blocking metastatic cell motility and bone directionality. [PDF]
Choi YJ +11 more
europepmc +1 more source
ABSTRACT Performance‐based assessments of sensory function provide essential insights into sensory integration challenges in autistic children and provide objective, standardized measurement data that can be used to tailor targeted interventions. We sought to evaluate the validity and reliability of data collected using the Evaluation in Ayres Sensory ...
Patricia Grady‐Dominguez +3 more
wiley +1 more source
<i>ACSL4</i>-driven ferroptosis susceptibility as a targetable vulnerability in monocytic acute myeloid leukemia. [PDF]
De Marchi F, Gottardi M.
europepmc +1 more source
Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert +6 more
wiley +1 more source
Steroid receptor coactivators in immunity - From function to emerging translational opportunities. [PDF]
Gilad Y, Lonard DM.
europepmc +1 more source

