Results 61 to 70 of about 133,957 (286)

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Relationships among tissues, biofluids, and otolith selenium concentrations in wild female burbot (Lota lota)

Integrated Environmental Assessment and Management, EarlyView., 2023
Abstract In the Lake Koocanusa‐Kootenai River system (Montana, USA and British Columbia, Canada), selenium (Se) contamination has become an international concern and is suspected to contribute to the observed burbot (Lota lota) population collapse. Due to our limited ability to sample burbot in Lake Koocanusa for monitoring studies, we used a reference
Stephanie D. Graves, Noëlie Molbert, David M. Janz, Lauren D. Hayhurst, Jessica E. Brandt, Lauren Timlick, Vince P. Palace   +6 more
wiley   +1 more source

Constraints on decay plus oscillation solutions of the solar neutrino problem [PDF]

, 2002
We examine the constraints on non-radiative decay of neutrinos from the observations of solar neutrino experiments. The standard oscillation hypothesis among three neutrinos solves the solar and atmospheric neutrino problems.
A. Acker, A. Acker, A. Acker, A. Bandyopadhyay, A.S. Joshipura, Anjan S. Joshipura, B.T. Cleveland, D.E. Groom, E. Massó, Eduard Massó, J. Bahcall, J. Bahcall, J. Bahcall, J.A. Frieman, J.N. Abdurashitov, J.N. Bahcall, J.N. Bahcall, J.N. Bahcall, J.N. Bahcall, John F. Beacom, M. Altmann, M. Apollonio, M. Lindner, Q.R. Ahmad, Q.R. Ahmed, Q.R. Ahmed, S. Choubey, S. Fukuda, S. Fukuda, Subhendra Mohanty, W. Hampel, Y. Fukuda   +31 more
core   +2 more sources

Controllable Dynamic Mechanical Cell Stimulation using Magnetically Actuated Artificial Cilia

Advanced Healthcare Materials, EarlyView.
This paper introduces a platform based on magnetic artificial cilia for providing controllable dynamic mechanical stimulation to single cells, suitable for investigating large cell populations and enabling live cell imaging. Proof‐of‐principle experiments show that cell morphology is strongly influenced by the artificial cilia, that cellular forces can
Roel Kooi, Tanveer Ul Islam, Oscar M.J.A. Stassen, Naomie Amsing, Jan de Boer, Jaap M.J. den Toonder   +5 more
wiley   +1 more source

Stoichiometry‐Programmed MXenes via Precursor Engineering for High‐Performance EMI Shielding and Energy Storage

Advanced Materials, EarlyView.
Precursor carbon stoichiometry programs internal strain and oxygen substitution in Ti3AlCxO2‐x, deterministically switching Ti3CxO2‐xTz MXenes between highly aligned 2D nanosheets and spontaneous 1D nanoscrolls. This synthesis‐stage architecture control enables ultrathin X/W‐band EMI shielding with outstanding mass‐normalized performance and bending ...
Jaeeun Park, Ju‐Hyoung Han, Yujin Chae, Mincheal Kim, Juwon Han, Younggeun Jang, Young Ho Jin, Jaewon Wang, Shi‐Hyun Seok, Yeoseon Sim, Zonghoon Lee, EunMi Choi, Soon‐Yong Kwon   +12 more
wiley   +1 more source

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

Advanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade, Ashna A. Kumar, Samuel O. Nitschke, Paul Joyce, Elahe Minaei, Stephanie E. Reuter Lange, Chelsea Penney, Holly Warren, Ruby Shepherd, Jeremy N. Dinoro, Gordon G. Wallace, Anthony Dosseto, Sameera Ansar, Naila Islam, Alistair Lochhead, George Sharbeen, Phoebe A. Phillips, Morteza Aghmesheh, Wayne J. Hawthorne, Kara L. Vine‐Perrow   +19 more
wiley   +1 more source

Enabling Real‐Time, Non‐Ionizing 3D Imaging of Implantable Magnetic Cements Using Magnetic Particle Imaging

Advanced Materials Interfaces, EarlyView.
This study reports the first implantable resin cement capable of orientation‐sensitive Magnetic Particle Imaging (MPI). By coating the cement with an ultrathin iron film, the authors achieve a strong, angle‐dependent MPI signal that enables non‐ionizing, real‐time tracking of both implant position and orientation, opening new possibilities for safe ...
Gabriel C. Pinto, João M. Costa, Simão P. Fernandes, Gabriela F. Resende, Eduardo T. C. Coimbra, Patrick Vogel, Mariana B. Oliveira, Marco Giardiello, Ricardo M. Silva, Armando A.C.S. Lourenço, Nuno J. O. Silva   +10 more
wiley   +1 more source

An educational tool to assist the design process of switched reluctance machines [PDF]

, 2016
The design of electric machines is a hot topic in the syllabuses of several undergraduate and graduate courses. With the development of hybrid and electrical vehicles, this subject is gaining more popularity, especially in electrical engineering ...
García Espinosa, Antonio, Riba Ruiz, Jordi-Roger, Romero, Itamar   +2 more
core   +2 more sources

Formation Control of Multi‐Agent System with Local Interaction and Artificial Potential Field

Advanced Robotics Research, EarlyView.
This article proposes a local interaction‐based formation control method for Multi‐Agent system, integrating consensus and leader‐follower strategies with a stress response mechanism—artificial potential field to reduce communication overhead and enable obstacle avoidance. Experimental results on triangular, square, and hexagonal formations confirm its
Luoyin Zhao, Zheping Yan, Yuqing Wang, Raye Chen‐Hua Yeow   +3 more
wiley   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source