Results 91 to 100 of about 40,396 (302)

Applications of Little's Law to stochastic models of gene expression

open access: yes, 2010
The intrinsic stochasticity of gene expression can lead to large variations in protein levels across a population of cells. To explain this variability, different sources of mRNA fluctuations ('Poisson' and 'Telegraph' processes) have been proposed in ...
Elgart, Vlad   +2 more
core   +1 more source

Oropouche virus: clinical, epidemiological, and molecular aspects of a neglected orthobunyavirus. [PDF]

open access: yes, 2017
Oropouche virus (OROV) is an important cause of arboviral illness in Latin American countries, more specifically in the Amazon region of Brazil, Venezuela and Peru, as well as in other countries such as Panama.
Acrani, Gustavo Olszanski   +6 more
core   +1 more source

Epigenetic regulation of mycorrhizal symbioses: from plastic responses to transgenerational legacies

open access: yesNew Phytologist, EarlyView.
Summary Mycorrhizal symbioses represent one of the most widespread and ecologically significant plant–microbe interactions, shaping plant nutrition, stress resilience, and ecosystem functioning. Beyond their role in nutrient exchange and systemic defense, growing evidence suggests that these symbioses also influence plant plasticity within and across ...
Gerson Beltrán‐Torres   +9 more
wiley   +1 more source

Genetic basis of sRNA quantitative variation analyzed using an experimental population derived from an elite rice hybrid

open access: yeseLife, 2015
We performed a genetic analysis of sRNA abundance in flag leaf from an immortalized F2 (IMF2) population in rice. We identified 53,613,739 unique sRNAs and 165,797 sRNA expression traits (s-traits).
Jia Wang   +4 more
doaj   +1 more source

Hfq‐dependent mRNA unfolding promotes sRNA‐based inhibition of translation

open access: yesEMBO Journal, 2019
Small RNAs post‐transcriptionally regulate many processes in bacteria. Base‐pairing of sRNAs near ribosome‐binding sites in mRNAs inhibits translation, often requiring the RNA chaperone Hfq. In the canonical model, Hfq simultaneously binds sRNAs and mRNA
Mirthe Hoekzema   +3 more
semanticscholar   +1 more source

Differentially Expressed Salivary miRNAs in Temporomandibular Disorders

open access: yesOrthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objective Temporomandibular disorders (TMDs) are heterogeneous conditions of unclear aetiology involving the temporomandibular joint, masticatory muscles and neural tissues. Limited understanding of their pathogenesis hampers accurate diagnosis and targeted treatment. Therefore, this study aimed to identify salivary microRNA (miRNA) signatures
Karolina Elżbieta Kaczor‐Urbanowicz   +13 more
wiley   +1 more source

sRNA‐FISH: versatile fluorescent in situ detection of small RNAs in plants

open access: yesThe Plant Journal, 2019
Localization of mRNA and small RNAs (sRNAs) is important for understanding their function. Fluorescent in situ hybridization (FISH) has been used extensively in animal systems to study the localization and expression of sRNAs.
Kun Huang   +3 more
semanticscholar   +1 more source

High‐Efficiency and Eco‐Friendly Management of Multiple Fungal Diseases by a Novel Carbon Dots sCDP Delivered RNA Nano‐Pesticides

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT RNA‐based pesticides represent a transformative approach in agricultural disease management, offering an environmentally sustainable alternative to conventional chemical fungicides. However, key challenges such as rapid RNA degradation in the environment and inefficient uptake hinder widespread adoption.
Chunhao Jiang   +10 more
wiley   +1 more source

A rhlI 5′ UTR-Derived sRNA Regulates RhlR-Dependent Quorum Sensing in Pseudomonas aeruginosa

open access: yesmBio, 2019
The opportunistic human pathogen Pseudomonas aeruginosa possesses multiple quorum sensing systems that regulate and coordinate production of virulence factors and adaptation to different environments.
Maureen K. Thomason   +10 more
semanticscholar   +1 more source

MicroRNA‐Induced Gene Silencing (MIGS): A Tool for Multi‐Gene Silencing and Targeting Viruses in Plants

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Since its discovery, RNA interference (RNAi, also known as gene silencing) has been a key tool to downregulate gene expression in plants for a range of applications, including protection against viruses. Many of these applications require the silencing of multiple genes concomitantly.
Marie‐Emilie A. Gauthier   +5 more
wiley   +1 more source

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