Results 1 to 10 of about 7,596,148 (257)

Gel-free library preparation for next-generation RNA sequencing and small RNA quantification [PDF]

Communications Biology
Next-generation RNA sequencing (RNA-seq) is hampered by “primer dimer” (PD) artifacts and its quantitative performance reduced by polymerase fall-off (PF) at RNA modifications and secondary structures. Here we improve RNA-seq efficiency by incorporating (
Ruixi Chen, Daniel Yim, Lili Liu, Michael S. DeMott, Bo Cao, Peter C. Dedon   +5 more
doaj   +2 more sources

Modeling early germline immunization after horizontal transfer of transposable elements reveals internal piRNA cluster heterogeneity

BMC Biology, 2023
Background A fraction of all genomes is composed of transposable elements (TEs) whose mobility needs to be carefully controlled. In gonads, TE activity is repressed by PIWI-interacting RNAs (piRNAs), a class of small RNAs synthesized by heterochromatic ...
Amna Asif-Laidin, Karine Casier, Zoheir Ziriat, Antoine Boivin, Elise Viodé, Valérie Delmarre, Stéphane Ronsseray, Clément Carré, Laure Teysset   +8 more
doaj   +1 more source

Mechanistic insights into non-coding Y RNA processing

RNA Biology, 2022
Y RNAs (84–112 nt) are non-coding RNAs transcribed by RNA polymerase III and are characterized by a distinctive secondary structure. Human Y RNAs interact with the autoimmune proteins SSB and RO60 that together form a ribonucleoprotein (RNP) complex ...
Martina Billmeier, Darrell Green, Adam E. Hall, Carly Turnbull, Archana Singh, Ping Xu, Simon Moxon, Tamas Dalmay   +7 more
doaj   +1 more source

Early Drought-Responsive Genes Are Variable and Relevant to Drought Tolerance

G3: Genes, Genomes, Genetics, 2020
Drought stress is an important crop yield limiting factor worldwide. Plant physiological responses to drought stress are driven by changes in gene expression.
Cheng He, Yicong Du, Junjie Fu, Erliang Zeng, Sunghun Park, Frank White, Jun Zheng, Sanzhen Liu   +7 more
doaj   +1 more source

The roles of small RNAs: insights from bacterial quorum sensing [PDF]

ExRNA, 2019
Ribonucleic acids (RNAs) mainly played auxiliary roles in regulations of genetic processes while recent explorations into small non-coding RNAs (sRNAs) in bacteria have broadened the scope of RNAs studies in these processes.
Hongchang Fu, Rosalía Cardós Elena, Paola Handal Marquez   +2 more
doaj   +1 more source

Environmentally-Induced Transgenerational Epigenetic Inheritance: Implication of PIWI Interacting RNAs

Cells, 2019
Environmentally-induced transgenerational epigenetic inheritance is an emerging field. The understanding of associated epigenetic mechanisms is currently in progress with open questions still remaining.
Karine Casier, Antoine Boivin, Clément Carré, Laure Teysset   +3 more
doaj   +1 more source

vtRNA2-1/nc886 Produces a Small RNA That Contributes to Its Tumor Suppression Action through the microRNA Pathway in Prostate Cancer

Non-Coding RNA, 2020
vtRNA2-1 is a vault RNA initially classified as microRNA precursor hsa-mir-886 and recently proposed as “nc886”, a new type of non-coding RNA involved in cancer progression acting as an oncogene and tumor suppressor gene in different tissues.
Rafael Sebastián Fort, Beatriz Garat, José Roberto Sotelo-Silveira, María Ana Duhagon   +3 more
doaj   +1 more source

Characterization of carbapenem-resistant Acinetobacter baumannii isolates in a Chinese teaching hospital

Frontiers in Microbiology, 2015
Carbapenem-resistant Acinetobacter baumannii (CRAB) presents a serious therapeutic and infection control challenge. In this study, we investigated the epidemiological and molecular differences of CRAB, and the threatening factors for contributing to ...
Yaowen eChang, Guangxin eLuan, Ying eXu, Yanhong eWang, Min eShen, Chi eZhang, Wei eZheng, Jinwei eHuang, Jingni eYang, Xu eJia, Baodong eLing   +10 more
doaj   +1 more source

sRNA23, a novel small RNA, regulates to the pathogenesis of Streptococcus suis serotype 2

Virulence, 2021
Streptococcus suis serotype 2 (S. suis 2) is an important ubiquitous zoonotic pathogen. To date, regulatory factors and their implication in S. suis pathogenesis are not fully understood.
Quanming Xu, Hong Chen, Wen Sun, Yongyi Zhang, Dewen Zhu, Kul Raj Rai, Ji-Long Chen, Ye Chen   +7 more
doaj   +1 more source

Molecular Characterization of Reduced Susceptibility to Biocides in Clinical Isolates of Acinetobacter baumannii

Frontiers in Microbiology, 2017
Active efflux is regarded as a common mechanism for antibiotic and biocide resistance. However, the role of many drug efflux pumps in biocide resistance in Acinetobacter baumannii remains unknown. Using biocide-resistant A.
Fei Lin, Fei Lin, Ying Xu, Yaowen Chang, Yaowen Chang, Chao Liu, Chao Liu, Xu Jia, Baodong Ling   +8 more
doaj   +1 more source