Results 11 to 20 of about 1,523,383 (315)

Accurate Adapter Information Is Crucial for Reproducibility and Reusability in Small RNA Seq Studies

open access: yesNon-Coding RNA, 2019
A necessary pre-processing data analysis step is the removal of adapter sequences from the raw reads. While most adapter trimming tools require adapter sequence as an essential input, adapter information is often incomplete or missing.
Xiangfu Zhong   +3 more
doaj   +2 more sources

An improved method for surface immobilisation of RNA: application to small Non-Coding RNA - mRNA pairing [PDF]

open access: yes, 2013
Characterisation of RNA and its intermolecular interactions is increasing in importance as the inventory of known RNA functions continues to expand. RNA-RNA interactions are central to post-transcriptional gene regulation mechanisms in bacteria, and the ...
Darren M. Gowers (485354)   +29 more
core   +1 more source

Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism [PDF]

open access: yes, 2010
For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degradation.
Andrzej Dziembowski   +3 more
core   +1 more source

sRNA23, a novel small RNA, regulates to the pathogenesis of Streptococcus suis serotype 2

open access: yesVirulence, 2021
Streptococcus suis serotype 2 (S. suis 2) is an important ubiquitous zoonotic pathogen. To date, regulatory factors and their implication in S. suis pathogenesis are not fully understood.
Quanming Xu   +7 more
doaj   +1 more source

Small RNA Cloning [PDF]

open access: yes, 2010
The next generation sequencing technologies have made the exhaustive sequencing of all small RNA species within a small RNA library possible. Thus, comparative studies on the changes in small-RNA transcriptomes between two biological samples represent a powerful means of revealing the functions of small RNAs in physiological and pathological processes.
Seungil, Ro, Wei, Yan
openaire   +2 more sources

Characterization of carbapenem-resistant Acinetobacter baumannii isolates in a Chinese teaching hospital

open access: yesFrontiers in Microbiology, 2015
Carbapenem-resistant Acinetobacter baumannii (CRAB) presents a serious therapeutic and infection control challenge. In this study, we investigated the epidemiological and molecular differences of CRAB, and the threatening factors for contributing to ...
Yaowen eChang   +10 more
doaj   +1 more source

Computational discovery of animal small RNA genes and targets [PDF]

open access: yes, 2007
Though recently discovered, small RNAs appear to play a wealth of regulatory roles, being involved in degradation of target mRNAs, translation silencing of target genes, chromatin remodeling and transposon silencing.
Gaidatzis, Dimosthenis
core   +1 more source

Molecular Characterization of Reduced Susceptibility to Biocides in Clinical Isolates of Acinetobacter baumannii

open access: yesFrontiers in Microbiology, 2017
Active efflux is regarded as a common mechanism for antibiotic and biocide resistance. However, the role of many drug efflux pumps in biocide resistance in Acinetobacter baumannii remains unknown. Using biocide-resistant A.
Fei Lin   +8 more
doaj   +1 more source

The ribose methylation enzyme FTSJ1 has a conserved role in neuron morphology and learning performance

open access: yesLife Science Alliance, 2023
This study adds insights into FTSJ1 tRNA 2′-O-methylation–associated pathologies in humans and Drosophila by identification of novel FTSJ1 targets and neuron morphology defects.
Mira Brazane   +20 more
doaj   +1 more source

AtXRN4 Affects the Turnover of Chosen miRNA*s in Arabidopsis

open access: yesPlants, 2020
Small RNA (sRNA) turnover is a key but poorly understood mechanism that determines the homeostasis of sRNAs. Animal XRN genes contribute the degradation of sRNAs, AtXRN2 and AtXRN3 also contribute the pri-miRNA processing and miRNA loop degradation in ...
Yan Liu   +7 more
doaj   +1 more source

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