Results 21 to 30 of about 1,523,383 (315)

RNA-specific ribonucleotidyl transferases [PDF]

open access: yes, 2007
RNA-specific nucleotidyl transferases (rNTrs) are a diverse family of template-independent polymerases that add ribonucleotides to the 3'-ends of RNA molecules.
Keller, W.   +3 more
core   +1 more source

Extracting Small RNAs from Human Biological Fluids for Subsequent Next-Generation Sequencing

open access: yesКреативная хирургия и онкология, 2019
A number of questions arise when choosing methods for experiments related to next-generation sequencing. On the one hand, while working with RNA extraction, added reagents and their residues can often inhibit sensitive chemicals with which the sequential
O. A. Beylerli   +2 more
doaj   +1 more source

Small RNAs in streptococci [PDF]

open access: yesRNA Biology, 2012
The group of streptococci includes species responsible for severe diseases in humans. To adapt to their environment and infect their hosts, streptococci depend on precise regulation of gene expression. The last decade has witnessed increasing findings of small RNAs (sRNAs) having regulatory functions in bacteria.
Anaïs, Le Rhun, Emmanuelle, Charpentier
openaire   +2 more sources

Ancient and novel small RNA pathways compensate for the loss of piRNAs in multiple independent nematode lineages [PDF]

open access: yes, 2015
Date of Acceptance: 02/01/2015Small RNA pathways act at the front line of defence against transposable elements across the Eukaryota. In animals, Piwi interacting small RNAs (piRNAs) are a crucial arm of this defence.
Jones, John T.   +60 more
core   +1 more source

Small RNA transcriptome analysis using parallel single-cell small RNA sequencing

open access: yesScientific Reports, 2023
miRNA and other forms of small RNAs are known to regulate many biological processes. Single-cell small RNA sequencing can be used to profile small RNAs of individual cells; however, limitations of efficiency and scale prevent its widespread application ...
Jia Li   +4 more
doaj   +1 more source

stepRNA: Identification of Dicer cleavage signatures and passenger strand lengths in small RNA sequences

open access: yesFrontiers in Bioinformatics, 2022
The enzyme Dicer is a component of many small RNA (sRNA) pathways involved in RNA processing for post-transcriptional regulation, anti-viral response and control of transposable elements.
Ben Murcott   +5 more
doaj   +1 more source

Silencing Dicer-Like Genes Reduces Virulence and sRNA Generation in Penicillium italicum, the Cause of Citrus Blue Mold

open access: yesCells, 2020
The Dicer protein is one of the most important components of RNAi machinery because it regulates the production of small RNAs (sRNAs) in eukaryotes. Here, Dicer1-like gene (Pit-DCL1) and Dicer2-like gene (Pit-DCL2) RNAi transformants were generated via ...
Chunxiao Yin   +4 more
doaj   +1 more source

Small RNAs and Immunity [PDF]

open access: yesImmunity, 2004
Small RNAs of 21-23 nucleotides are powerful regulators of gene expression and play essential roles in biological processes that include development, maintenance of genome stability, and viral adaptive defense mechanisms. Such small RNAs are simple in design yet rich in biology and have captivated the attention of biologists in many fields. This review
openaire   +2 more sources

Emerging role of a novel small non-coding regulatory RNA: tRNA-derived small RNA [PDF]

open access: yesExRNA, 2019
The discovery of small non-coding RNAs, such as miRNA and piRNA, has dramatically changed our understanding of the role RNA plays in organisms. Recent studies show that a novel small non-coding RNA generated from cleavage of tRNA or pre-tRNA, called tRNA-
Fangfang Jin, Zhigang Guo
doaj   +1 more source

Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS [PDF]

open access: yes, 2013
: OxyS and RprA are two small noncoding RNAs (sRNAs) that modulate the expression of rpoS, encoding an alternative sigma factor that activates transcription of multiple Escherichia coli stress-response genes.
Taylor, James E.   +28 more
core   +1 more source

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