mSphere, 2021 Juvenile pacific oysters have been subject in recent years to summer mortality episodes with deep economic consequences.
Xing Luo +3 more
doaj +3 more sources
Mining small RNA structure elements in untranslated regions of human and mouse mRNAs using structure-based alignment [PDF]
BMC Genomics, 2008 Background UnTranslated Regions (UTRs) of mRNAs contain regulatory elements for various aspects of mRNA metabolism, such as mRNA localization, translation, and mRNA stability.
Wen Dongrong +4 more
doaj +3 more sources
Small interfering RNA targeted to stem-loop II of the 5' untranslated region effectively inhibits expression of six HCV genotypes [PDF]
Virology Journal, 2006 Background The antiviral action of interferon alpha targets the 5' untranslated region (UTR) used by hepatitis C virus (HCV) to translate protein by an internal ribosome entry site (IRES) mechanism.
Dash Srikanta +2 more
doaj +4 more sources
Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos [PDF]
Nature Communications, 2021 Abstract Inheritance and clearance of maternal mRNAs are two of the most critical events required for animal early embryonic development. However, the mechanisms regulating this process are still largely unknown. Here, we show that together with maternal mRNAs, C.
Piergiuseppe Quarato +7 more
openaire +5 more sources
Expression of the ISPpu9 transposase of Pseudomonas putida KT2440 is regulated by two small RNAs and the secondary structure of the mRNA 5′-untranslated region [PDF]
Nucleic Acids Research, 2021 Abstract Insertion sequences (ISs) are mobile genetic elements that only carry the information required for their own transposition. Pseudomonas putida KT2440, a model bacterium, has seven copies of an IS called ISPpu9 inserted into repetitive extragenic palindromic sequences. This work shows that the gene for ISPpu9 transposase, tnp, is
Guillermo Gómez-García +4 more
openaire +3 more sources
Weight Change Alters the Small RNA Profile of Urinary Extracellular Vesicles in Obesity
Obesity Facts, 2022 Introduction: Various kidney diseases reportedly show different urinary extracellular vesicle (EV) RNA profiles. Although obesity is one of the main causes of chronic kidney disease, the expression pattern of urinary EV RNA in obesity is uncertain.
Dughyun Choi +12 more
doaj +1 more source
Small Untranslated RNA Antitoxin inBacillus subtilis [PDF]
Journal of Bacteriology, 2005 ABSTRACTToxin-antitoxin (TA) modules are pairs of genes in which one member encodes a toxin that is neutralized or whose synthesis is prevented by the action of the product of the second gene, an antitoxin, which is either protein or RNA. We now report the identification of a TA module in the chromosome ofBacillus subtilisin which the antitoxin is an ...
Jessica M, Silvaggi +2 more
openaire +2 more sources
Developmental mRNA clearance by PIWI-bound endo-siRNAs in Paramecium
Cell Reports, 2023 Summary: The clearance of untranslated mRNAs by Argonaute proteins is essential for embryonic development in metazoans. However, it is currently unknown whether similar processes exist in unicellular eukaryotes. The ciliate Paramecium tetraurelia harbors
Therese Solberg +3 more
doaj +1 more source
Migration of Small Ribosomal Subunits on the 5′ Untranslated Regions of Capped Messenger RNA [PDF]
International Journal of Molecular Sciences, 2019 Several control mechanisms of eukaryotic gene expression target the initiation step of mRNA translation. The canonical translation initiation pathway begins with cap-dependent attachment of the small ribosomal subunit (SSU) to the messenger ribonucleic acid (mRNA) followed by an energy-dependent, sequential ‘scanning’ of the 5′ untranslated regions ...
Nikolay E. Shirokikh +4 more
openaire +5 more sources
Retraction Note: Small interfering RNA targeted to stem-loop II of the 5′ untranslated region effectively inhibits expression of six HCV genotypes [PDF]
Virology Journal, 2021 The antiviral action of interferon alpha targets the 5' untranslated region (UTR) used by hepatitis C virus (HCV) to translate protein by an internal ribosome entry site (IRES) mechanism. Although this sequence is highly conserved among different clinical strains, approximately half of chronically infected hepatitis C patients do not respond to ...
Ramesh Prabhu +2 more
openaire +2 more sources