Characterization of the Small Untranslated RNA RyhB and Its Regulon inVibrio cholerae [PDF]
Journal of Bacteriology, 2005 ABSTRACTNumerous small untranslated RNAs (sRNAs) have been identified inEscherichia coliin recent years, and their roles are gradually being defined. However, few of these sRNAs appear to be conserved inVibrio cholerae, and both identification and characterization of sRNAs inV. choleraeremain at a preliminary stage. We have characterized one of the few
Brigid M, Davis +4 more
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Cell Reports, 2020 Summary: Bacterial pathogens often employ RNA regulatory elements located in the 5′ untranslated regions (UTRs) to control gene expression. Using a comparative structural analysis, we examine the structure of 5′ UTRs at a global scale in the pathogenic ...
Dmitriy Ignatov +10 more
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Satellite RNA-Derived Small Interfering RNA satsiR-12 Targeting the 3′ Untranslated Region of Cucumber Mosaic Virus Triggers Viral RNAs for Degradation [PDF]
Journal of Virology, 2011 ABSTRACT RNA silencing provides protection against RNA viruses by targeting both the helper virus and its satellite RNA (satRNA). Virus-derived small interfering RNAs (vsiRNAs) bound with Argonaute (AGO) proteins are presumed participants in the silencing process.
Hui, Zhu +6 more
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Genome-wide double-stranded RNA sequencing reveals the functional significance of base-paired RNAs in Arabidopsis. [PDF]
PLoS Genetics, 2010 The functional structure of all biologically active molecules is dependent on intra- and inter-molecular interactions. This is especially evident for RNA molecules whose functionality, maturation, and regulation require formation of correct secondary ...
Qi Zheng +8 more
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Cells, 2021 Ribosomal proteins (RPs) are mostly derived from the energy-consuming enzyme families such as ATP-dependent RNA helicases, AAA-ATPases, GTPases and kinases, and are important structural components of the ribosome, which is a supramolecular ...
Abu Musa Md Talimur Reza, Yu-Guo Yuan
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New Insight about of microRNAs & short interfering RNA in Treatment of COVID-19; a Narrative Review
Men's Health Journal, 2022 Since 31 December 2019, the coronavirus disease 2019 (COVID-19) resulted in a state of hyperinflammation syndrome and multiorgan failure. In areas with pandemic outbreaks, despite several emerging vaccines, supportive treatments to mitigate fatality ...
Mohammad Ali Salahshoor, Reza Mahjub
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Frontiers in Chemistry, 2021 G-quadruplexes are believed to have important biological functions, so many small molecules have been screened or developed for targeting G-quadruplexes.
Xiao-Xia Hu +12 more
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SUMO-Modification of the La Protein Facilitates Binding to mRNA In Vitro and in Cells. [PDF]
PLoS ONE, 2016 The RNA-binding protein La is involved in several aspects of RNA metabolism including the translational regulation of mRNAs and processing of pre-tRNAs.
Venkatesh Kota +6 more
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Inhibition of hepatitis C virus IRES-mediated translation by small RNAs analogous to stem-loop structures of the 5'-untranslated region [PDF]
Nucleic Acids Research, 2004 Translation of the hepatitis C virus (HCV) RNA is mediated by the interaction of ribosomes and cellular proteins with an internal ribosome entry site (IRES) located within the 5'-untranslated region (5'-UTR). We have investigated whether small RNA molecules corresponding to the different stem-loop (SL) domains of the HCV IRES, when introduced in trans,
Ray, Partho Sarothi, Das, Saumitra
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A small yeast RNA selectively inhibits internal initiation of translation programmed by poliovirus RNA: specific interaction with cellular proteins that bind to the viral 5'-untranslated region [PDF]
Journal of Virology, 1994 We have purified, sequenced, and prepared a synthetic clone of a small (60-nucleotide) RNA molecule from the yeast Saccharomyces cerevisiae that had previously been isolated on the basis of its ability to selectively block the translation of poliovirus mRNA. RNA derived from the clone by transcription with T7 RNA polymerase appears to block translation
S, Das, P, Coward, A, Dasgupta
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