Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS [PDF]
OxyS and RprA are two small noncoding RNAs (sRNAs) that modulate the expression of rpoS, encoding an alternative sigma factor that activates transcription of multiple Escherichia coli stress-response genes. While RprA activates rpoS for translation, OxyS
Callaghan, Anastasia +9 more
core +1 more source
Grad‐seq in a Gram‐positive bacterium reveals exonucleolytic sRNA activation in competence control
RNA–protein interactions are the crucial basis for many steps of bacterial gene expression, including post‐transcriptional control by small regulatory RNAs (sRNAs). In stark contrast to recent progress in the analysis of Gram‐negative bacteria, knowledge
Jens Hör +8 more
semanticscholar +1 more source
Background The RNA interference (RNAi) pathway is a gene regulation mechanism that utilizes small RNA (sRNA) and Argonaute (Ago) proteins to silence target genes.
Hanbang Zhang +3 more
doaj +1 more source
Hierarchy in Hfq Chaperon Occupancy of Small RNA Targets Plays a Major Role in Their Regulation
Summary: Bacterial small RNAs (sRNAs) are posttranscriptional regulators of gene expression that base pair with complementary sequences on target mRNAs, often in association with the chaperone Hfq. Here, using experimentally identified sRNA-target pairs,
Raya Faigenbaum-Romm +5 more
doaj +1 more source
Identification of small RNAs abundant in Burkholderia cenocepacia biofilms reveal putative regulators with a potential role in carbon and iron metabolism [PDF]
Small RNAs play a regulatory role in many central metabolic processes of bacteria, as well as in developmental processes such as biofilm formation. Small RNAs of Burkholderia cenocepacia, an opportunistic pathogenic beta-proteobacterium, are to date not ...
Coenye, Tom +2 more
core +3 more sources
A novel mechanism underlying the innate immune response induction upon viral-dependent replication of host cell mRNA: A mistake of +sRNA viruses' replicases [PDF]
Viruses are lifeless particles designed for setting virus-host interactome assuring a new generation of virions for dissemination. This interactome generates a pressure on host organisms evolving mechanisms to neutralize viral infection, which places the
Colombo, Maria Isabel +1 more
core +6 more sources
Myths about violence among judiciary professionals [PDF]
The presence of myths about violence (mistaken, but resilient and broadly shared opinions) among those professionals who deal with violence in their work could interfere with their educational advancement and professional development.
Srna Jelena, Tenjović Lazar
doaj +1 more source
Small RNAs (sRNAs) play a very important role in gene regulation at the posttranscriptional level. However, sRNAs from nonmodel microorganisms, extremophiles in particular, have been rarely explored.
Jiao Wen +5 more
doaj +1 more source
Baked licorice-derived sRNA alleviates lung injury mild ARDS mouse models possibly through targeting TNF-α [PDF]
Objective To explore the effect and mechanism of small RNA(sRNA)targeting at TNF-α in acute respiratory distress syndrome (ARDS). Methods Taking TNF-α as the target, screen sRNA from the sRNA database of Sini decoction by bioinformatics ...
JIANG Zhenyu, WANG Xiaona, TANG Kegong, CHEN Mingrui, JIANG Chengyu
doaj +1 more source
ARGONAUTE PIWI domain and microRNA duplex structure regulate small RNA sorting in Arabidopsis. [PDF]
Small RNAs (sRNAs) are loaded into ARGONAUTE (AGO) proteins to induce gene silencing. In plants, the 5'-terminal nucleotide is important for sRNA sorting into different AGOs.
Carbonell, Alberto +9 more
core +2 more sources

