Results 41 to 50 of about 14,887 (192)

sRNATargetDigger: A bioinformatics software for bidirectional identification of sRNA-target pairs with co-regulatory sRNAs information.

PLoS ONE, 2020
Identification of the target genes of microRNAs (miRNAs), trans-acting small interfering RNAs (ta-siRNAs), and small interfering RNAs (siRNAs) is an important step for understanding their regulatory roles in plants.
Xinghuo Ye, Zhihong Yang, Yeqin Jiang, Lan Yu, Rongkai Guo, Yijun Meng, Chaogang Shao   +6 more
doaj   +1 more source

Hfq CLASH uncovers sRNA-target interaction networks linked to nutrient availability adaptation

eLife, 2020
By shaping gene expression profiles, small RNAs (sRNAs) enable bacteria to efficiently adapt to changes in their environment. To better understand how Escherichia coli acclimatizes to nutrient availability, we performed UV cross-linking, ligation and ...
Ira Alexandra Iosub, Robert Willem van Nues, Stuart William McKellar, Karen Jule Nieken, Marta Marchioretto, Brandon Sy, Jai Justin Tree, Gabriella Viero, Sander Granneman   +8 more
doaj   +1 more source

The problem of corporal punishment of children and role of experts in its solving [PDF]

Temida, 2010
Corporal punishment of children is a serious social problem and as such more and more recognized around the world and in recent years in our environment as well.
Srna Jelena, Stevanović Ivana
doaj   +1 more source

Sibling sRNA RyfA1 Influences Shigella dysenteriae Pathogenesis [PDF]

Genes, 2017
Small regulatory RNAs (sRNAs) of Shigella dysenteriae and other pathogens are vital for the regulation of virulence-associated genes and processes. Here, we characterize RyfA1, one member of a sibling pair of sRNAs produced by S. dysenteriae. Unlike its nearly identical sibling molecule, RyfA2, predicted to be encoded almost exclusively by non ...
Megan Fris, William Broach, Sarah Klim, Peter Coschigano, Ronan Carroll, Clayton Caswell, Erin Murphy   +6 more
openaire   +3 more sources

RNA degradomics and proteomics reveal the mechanism of dsProsβ1‐mediated proteasome targeting in Psylliodes chrysocephala

Pest Management Science, EarlyView.
RNA degradomics revealed dsProsβ1‐derived siRNA‐mediated mRNA cleavage events, mainly at uracil‐guanine and adenine‐adenine pairs. Proteasome inhibition via dsProsβ1 increased mitochondrial and cytoskeletal proteins while reducing translation‐related and mRNA‐binding proteins.
Doga Cedden, Gözde Güney, Michael Rostás, Stefan Scholten   +3 more
wiley   +1 more source

Novel application of sRNA: Stimulation of ribosomal frameshifting: FIGURE 1. [PDF]

RNA, 2004
Small RNAs play an important role in regulation of gene expression in eukaryotic and eubacterial cells by modulating gene expression both at the level of transcription and translation. Here, we show that short complementary RNAs can also affect gene expression by stimulating ribosomal frameshifting in vitro.
Olsthoorn, R.R.C.L., Laurs, M., Sohet, F., Hilbers, C.W., Heus, H.A., Pleij, C.W.A.   +5 more
openaire   +4 more sources

Iflaviruses in arthropods: when small is mighty

Insect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia, Hannah‐Isadora Huditz, Monique M. van Oers, Vera I.D. Ros   +3 more
wiley   +1 more source

A conserved stem of the Myxococcus xanthus sRNA Pxr controls sRNA accumulation and multicellular development [PDF]

Scientific Reports, 2017
AbstractThe small RNA (sRNA) Pxr negatively controls multicellular fruiting body formation in the bacterium Myxococcus xanthus, inhibiting the transition from growth to development when nutrients are abundant. Like many other prokaryotic sRNAs, Pxr is predicted to fold into three stem loops (SL1-SL3).
Yu, Yuen-Tsu N., Cooper, Elizabeth, Velicer, Gregory J.   +2 more
openaire   +3 more sources

Characterization of the dynamic microbiome evolution across thrips species

Insect Science, EarlyView.
Comprehensive survey of the microbiome in thrips. The dominant bacterial genera found in thrips include intracellular ones, such as Wolbachia and Spiroplasma, and extracellular ones, including Serratia, Pantoea, and Acinetobacter. We isolated and sequenced high‐quality genomes of two dominant symbionts, Pantoea dispersa and Serratia marcescens.
Xiaodi Hu, Zhaohui Shi, Yangwei Gao, Hanze Zheng, Lin Lin, Jian‐Ping Chen, Yong Chen, Chuan‐Xi Zhang, Yiyuan Li   +8 more
wiley   +1 more source

Global analysis of sRNA target genes in Mycoplasma hyopneumoniae

BMC Genomics, 2018
Background Small RNAs (sRNAs) are noncoding molecules that regulate different cellular activities in several bacteria. The role of sRNAs in gene expression regulation is poorly characterized in the etiological agent of porcine enzootic pneumonia ...
Tiago Ebert Fritsch, Franciele Maboni Siqueira, Irene Silveira Schrank   +2 more
doaj   +1 more source