Results 21 to 30 of about 23,078 (241)
Molecular mechanism of cargo recognition and handover by the mammalian signal recognition particle
Summary: Co-translational protein targeting to membranes by the signal recognition particle (SRP) is a universally conserved pathway from bacteria to humans.
Ahmad Jomaa +6 more
doaj +1 more source
Kinship in the SRP RNA family [PDF]
The signal recognition particle (SRP) is a ribonucleoprotein complex which participates in the targeting of protein to cellular membranes. The RNA component of the SRP has been found in all domains of life, but the size of the molecule and the number of RNA secondary structure elements vary considerably between the different phylogenetic groups.
Magnus Alm, Rosenblad +3 more
openaire +2 more sources
Molecular Crosstalk between the Nucleotide Specificity Determinant of the SRP GTPase and the SRP Receptor [PDF]
In signal recognition particle (SRP)-dependent targeting of proteins to the bacterial plasma membrane, two GTPases, Ffh (the SRP GTPase) and FtsY (the receptor GTPase), form a complex in which both proteins reciprocally stimulate each other's GTPase activities.
Shan, Shu-ou, Walter, Peter
openaire +3 more sources
The interaction network of the YidC insertase with the SecYEG translocon, SRP and the SRP receptor FtsY [PDF]
AbstractYidC/Oxa1/Alb3 are essential proteins that operate independently or cooperatively with the Sec machinery during membrane protein insertion in bacteria, archaea and eukaryotic organelles. Although the interaction between the bacterial SecYEG translocon and YidC has been observed in multiple studies, it is still unknown which domains of YidC are ...
Narcis-Adrian Petriman +7 more
openaire +3 more sources
The installation of high-capacity fast electric vehicle (EV) chargers at the residential level is posing a significant risk to the distribution grid.
Mohammad GOLGOL +5 more
doaj +1 more source
Biogenesis of the Signal Recognition Particle (Srp) Involves Import of Srp Proteins into the Nucleolus, Assembly with the Srp-Rna, and Xpo1p-Mediated Export [PDF]
The signal recognition particle (SRP) targets nascent secretory proteins to the ER, but how and where the SRP assembles is largely unknown. Here we analyze the biogenesis of yeast SRP, which consists of an RNA molecule (scR1) and six proteins, by localizing all its components.
H, Grosshans +3 more
openaire +2 more sources
Assessing the impact of social housing on urban regeneration in South African cities
Urban regeneration in South Africa addresses historical spatial inequalities and the growing demand for affordable housing. This study examines the impact of social housing on urban regeneration, with a particular focus on the role of the Social Housing ...
Noxolo N. Ngema +2 more
doaj +1 more source
Targeting inflammatory pathways is considered a common strategy to control type 2 diabetes (T2D) and periodontitis. This overview was to validate systemic antibiotics as an adjuvant to scaling and root planing (SRP) for the treatments of periodontal ...
Shih-Yun Wu +6 more
doaj +1 more source
Background and objective The aim of this study was to elucidate the clinical and myopathological characteristics of patients with anti-signal recognition particle (SRP) positive immune-mediated necrotizing myopathy (IMNM) overlap Sjogren’s syndrome (SS).
Li Xu +4 more
doaj +1 more source
Objective: The aim of this study was to evaluate the effects of probiotic (PRO) Lactobacillus reuteri (DSM17938) as an adjuvant to the treatment of experimental periodontitis (EP). Material and methods: Fifty-four male adult Wistar rats were included. EP
Valdir Gouveia Garcia +7 more
doaj +1 more source

