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The Sheffield RNAi Screening Facility (SRSF): Portfolio Growth and Technology Development
The Sheffield RNAi Screening Facility (SRSF) (www.rnai.group.shef.ac.uk) was established in 2008 with Wellcome Trust and University of Sheffield funding, with the task to provide the first UK RNAi screening resource for academic groups interested in identifying genes required in a diverse range of biological processes using Drosophila cell culture. The
Stephen Brown
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Bim is a member of the pro‐apoptotic BH3‐only Bcl‐2 family of proteins. Bim gene undergoes alternative splicing to produce three predominant splicing variants (BimEL, BimL and BimS). The smallest variant BimS is the most potent inducer of apoptosis. Zinc (Zn2+) has been reported to stimulate apoptosis in various cell types.
Hirokazu, Hara +6 more
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Abstract Breast cancer is the most common cancer in women worldwide, and luminal/estrogen receptor positive (ER+) breast cancer accounts for ∼50% of breast cancer deaths. Our lab has identified serine auxotrophy as a metabolic vulnerability of luminal/ER+ breast tumors due to low levels of the serine synthesis enzyme phosphoserine ...
Philippa Burns +7 more
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Breast cancer is the most common cancer in women worldwide, and luminal/estrogen receptor positive (ER+) breast cancer accounts for ∼50% of breast cancer deaths. Our lab has identified serine auxotrophy as a metabolic vulnerability of luminal/ER+ breast tumors due to low levels of the serine synthesis enzyme phosphoserine aminotransferase 1 (PSAT1 ...
Philippa Burns +7 more
openaire +2 more sources
SRSF formår ikke at tale til følelserne
Friis Larsen, Michael +4 more
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