RBM15 Mediated m6A Modification of SRSF1 Inhibits Cuproptosis in Non‐Small Cell Lung Cancer by Mediating ATP7B Alternative Splicing [PDF]
Kaohsiung Journal of Medical SciencesInhibition of cuproptosis contributes to the development of non‐small cell lung cancer (NSCLC). The expression of RNA‐binding motif protein 15 (RBM15) is upregulated in NSCLC. Nonetheless, its relationship with cuproptosis remains unclear.
Shan‐shan Mao +3 more
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High expression of SRSF1 facilitates osteosarcoma progression and unveils its potential mechanisms [PDF]
BMC CancerBackground SRSF1, a member of Serine/Arginine-Rich Splicing Factors (SRSFs), has been observed to significantly influence cancer progression. However, the precise role of SRSF1 in osteosarcoma (OS) remains unclear.
Shuqi Li +5 more
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Cyperotundone promotes chemosensitivity of breast cancer via SRSF1 [PDF]
Frontiers in PharmacologyBreast cancer is among the most common malignancies and the leading cause of cancer-related deaths in women. SRSF1 proteins belong to an important splicing factor (SF) family and bind to different splicing regulatory elements (SREs) to promote or inhibit
Chao Li +8 more
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SRSF1 promotes proliferation, invasion and migration of esophageal squamous cell carcinoma Eca9706 cells by regulating VEGFA mRNA alternative splicing [PDF]
Zhongguo aizheng zazhi, 2022 Background and purpose: Serine/arginine-rich splicing factor 1 (SRSF1) is closely related to the development of tumor. Esophageal carcinoma is the common malignant tumor of digestive system.
DUAN Yuqing, XIA Ning, JIA Yunlong, ZHENG Wenya, LIU Lihua
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Prognostic Value of the Immunohistochemical Expression of Serine and Arginine-Rich Splicing Factor 1 (SRSF1) in Uveal Melanoma: A Clinico-Pathological and Immunohistochemical Study on a Series of 85 Cases [PDF]
Applied Sciences, 2021 Uveal melanoma (UM) is the most frequent primary ocular malignancy of adults; it exhibits an almost invariably poor prognosis with onset of liver metastases within 10–15 years after the diagnosis.
Giuseppe Broggi +14 more
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iScience, 2023 Summary: Oral squamous cell carcinoma (OSCC) is a common cancer of the head and neck. Despite ongoing efforts, there remains a dearth of targeted drugs capable of effectively inhibiting OSCC growth.
Yi Qu +4 more
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Journal of Hepatocellular Carcinoma, 2023 Zhilu Yao,1,2,* Ning Liu,3,* Hui Lin,1 Yingqun Zhou2,4 1Department of Gastroenterology, Jingan District Zhabei Central Hospital, Shanghai, 200072, People’s Republic of China; 2Clinical Medical College of Shanghai Tenth People’s Hospital, Nanjing ...
Yao Z, Liu N, Lin H, Zhou Y
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Supplementary Material_IJMS-circSLC41A1-miR-9820-5p-SRSF1
, 2021 S1 ; S2 ; S3 miR-9820-5p ssc-circSLC41A1/ SRSF1 ; S7 FISH ; S1 miR-9820-5p
Huiming Wang
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Serine Arginine-Rich Splicing Factor 1 (SRSF1) Contributes to the Transcriptional Activation of CD3ζ in Human T Cells. [PDF]
PLoS ONE, 2015 T lymphocytes from many patients with systemic lupus erythematosus (SLE) express decreased levels of the T cell receptor (TCR)-associated CD3 zeta (ζ) signaling chain, a feature directly linked to their abnormal phenotype and function.
Vaishali R Moulton +4 more
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SRSF1 regulates exosome microRNA enrichment in human cancer cells [PDF]
Cell Communication and Signaling, 2020 Background Exosomes are extracellular vesicles containing a variety of biological molecules including microRNAs (miRNAs). We have recently demonstrated that certain miRNA species are selectively and highly enriched in pancreatic cancer exosomes with miR ...
Yi-Fan Xu +7 more
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