Results 131 to 140 of about 210,179 (329)

Psilocybin in alcohol use disorder and comorbid depressive symptoms: Results from a feasibility randomized clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psilocybin has emerged as a potential treatment for alcohol use disorder (AUD), but early efficacy data are inconsistent. Depression following alcohol detoxification significantly increases the risk of relapse. This pilot study aimed to evaluate the feasibility, acceptability, and preliminary efficacy of psilocybin‐assisted
Amandine Luquiens, Dahbia Belahda, Carine Graux, Noe Igounenc, Chris Serrand, Paul Rochefort, Thibault Mura, Felix Sergent   +7 more
wiley   +1 more source

Fitting Heterogeneous Lanchester Models on the Kursk Campaign

, 2019
The battle of Kursk between Soviet and German is known to be the biggest tank battle in the history. The present paper uses the tank and artillery data from the Kursk database for fitting both forms of homogeneous and heterogeneous Lanchester model ...
Das, Sumanta Kumar
core  

5‐Methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) for alcohol use disorder: An open‐label, phase 2, proof‐of‐concept, clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden, Michael Kelleher, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, Claire Roberts, James J. Rucker, Gemma Scott, Ivan Saeger, Francesca Small, Mathieu Seynaeve   +10 more
wiley   +1 more source

Cost‐Effectiveness of Venom Immunotherapy in Preventing Severe Bee and Wasp Sting Reactions

Allergy, EarlyView.
This study evaluates the cost‐effectiveness of Hymenoptera venom depot immunotherapy (HVDI) with Alutard SQ compared to adrenaline auto‐injectors (AAIs) in Denmark. The model incorporates both psychological and physiological benefits to estimate quality‐adjusted life years (QALYs).
Gunter Sturm, Maria Beatrice Bilò, Carmen Vidal, Joanna N.G. Oude Elberink, Jochen Schmitt, Andreas Kallsoy Slættanes, Thilo Jakob   +6 more
wiley   +1 more source

Exposures in Indoor Air Affecting Health

Allergy, EarlyView.
ABSTRACT Indoor air quality (IAQ) is influenced by a wide range of chemical, biological and physical agents that can negatively impact physical, immunological and mental health. Adverse health effects depend on the type and concentration of pollutants, duration of exposure, and individual susceptibility.
Maria Hartiala, Varpu Elenius, Alicia Aguado Pesquera, Silas Androulakis, Isabella Annesi‐Maesano, Artur Badyda, Sicco Brandsma, Ioanna Chatziprodromidou, Goran Gajski, Judith Garcia‐Aymerich, Chiara Giorio, Timo Hugg, Jouni J. K. Jaakkola, Sarah Koch, Pim E. G. Leonards, Angeliki Matrali, Lisa Melymuk, Natalie Mueller, Adam Muszyński, Jet Opbroek, Inês Paciência, Spyros N. Pandis, Sofya Pozdniakova, Aino K. Rantala, Sandra Rodríguez Sufuentes, Linda Schenk, Eva Sugeng, Adrià Sunyer‐Caldú, Apostolos Vantarakis, Alexander Zherebker, Ernesto Alfaro‐Moreno, Pernilla Bohlin Nizzetto, José Fermoso Dominguez, Stylianos Karatzas, Francesco Mureddu, Heidi Salonen, Nikolaos Papadopoulos, Tuomas Jartti, the IDEAL Consortium   +38 more
wiley   +1 more source

Development of a nomogram for sperm retrieval at microTESE for idiopathic non‐obstructive azoospermia in a multi‐center cohort study

Andrology, EarlyView.
Abstract Background Non‐obstructive azoospermia (NOA) affects approximately 10% of infertile men and represents a major challenge in assisted reproductive technology (ART). A model that includes histological variants could be helpful in predicting sperm retrieval rate (SRR) after microdissection testicular sperm extraction (mTESE) in patients affected ...
Giorgio Ivan Russo, Edoardo Pozzi, Fausto Negri, Marco Falcone, Emanuele Zupo, Mirko Preto, Maria Giovanna Asmundo, Sandrine Chamayou, Murat Dursun, Ateş Kadıoğlu, Andrea Salonia   +10 more
wiley   +1 more source

Dynamic 16S rRNA Sequencing of the Abdominal Wall Surgical Site Highlights Potential Pathways of Incisional Surgical Site Infection in Colorectal Surgery

ANZ Journal of Surgery, EarlyView.
ABSTRACT Introduction Understanding the microbial changes within the surgical site may enhance our understanding of the origin and subsequent role of microbes in the causation of incisional surgical site infections (SSIs). In this study we used 16S rRNA sequencing to establish the dynamic microbiota of the surgical site in patients undergoing bowel ...
Veral Vishnoi, Emily C. Hoedt, Matthew Watson, Madelyn Gramlick, Michelle Zhao, Natalie Lott, Rosemary Carroll, Peter Pockney, Stephen R. Smith, Simon Keely   +9 more
wiley   +1 more source

Climatic Variables and Virulence May Contribute to the Population Dynamics of Pyricularia oryzae at Local Scale. [PDF]

Microbiologyopen
The Italian population structure of P. oryzae was analyzed using SSR genotyping to identify possible determinants shaping its local genetic diversity, including spatial, temporal, environmental, and biological factors. ABSTRACT Rice blast disease, caused by Pyricularia oryzae Cavara, is the most threatening rice pathogen in Italy.
Bosco S, Sillo F, Ruffa P, Bergonzi L, Tenni D, Abbruscato P, Torello Marinoni D, Romani M, Spadaro D.   +8 more
europepmc   +2 more sources

Metastatic potential of small posterior uveal melanomas

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate the prevalence of aggressive traits in small posterior uveal melanomas (UM). Methods This retrospective, multicentre cohort study included 804 patients with small posterior UM (≤9 mm in largest basal diameter, ≤3 mm in thickness) from centres in the UK, Germany, and Sweden.
Gustav Stålhammar, Helen Kalirai, Sarah E. Coupland, Salvatore Grisanti, Svenja Rebecca Sonntag, Ayseguel Tura, Antonio Eleuteri, Rumana N. Hussain, Heinrich Heimann, Hannah Coudé Adam   +9 more
wiley   +1 more source

A comparative greenness assessment of chromatographic methods for cilnidipine analysis and its combination

Green Analytical Chemistry
The greenness assessment of analytical methods is an important aspect of green analytical chemistry, which focuses on making analytical procedures eco-friendly and safer.
Kavita Suthar, Sonal Desai
doaj   +1 more source