Results 121 to 130 of about 192,408 (300)

Burrow Persistence and Spatial Distribution of Federally and State‐Protected Gopher Tortoise (Gopherus polyphemus) Populations in Southwest Alabama

Animal Conservation, EarlyView.
The gopher tortoise (Gopherus polyphemus), a keystone species and ecosystem engineer, has declined by ~80% over the past century due to primarily habitat loss. In a 28‐year resurvey of federally protected Mobile County and state‐protected Baldwin County, we found tortoise populations persisted at ~59% and ~31% of sites, respectively, with significant ...
Robin B. Lloyd Jr., Jeremiah A. Henning, Steven R. Schultze, David H. Nelson, Adam D. Chupp   +4 more
wiley   +1 more source

Psilocybin in alcohol use disorder and comorbid depressive symptoms: Results from a feasibility randomized clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psilocybin has emerged as a potential treatment for alcohol use disorder (AUD), but early efficacy data are inconsistent. Depression following alcohol detoxification significantly increases the risk of relapse. This pilot study aimed to evaluate the feasibility, acceptability, and preliminary efficacy of psilocybin‐assisted
Amandine Luquiens, Dahbia Belahda, Carine Graux, Noe Igounenc, Chris Serrand, Paul Rochefort, Thibault Mura, Felix Sergent   +7 more
wiley   +1 more source

5‐Methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) for alcohol use disorder: An open‐label, phase 2, proof‐of‐concept, clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden, Michael Kelleher, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, Claire Roberts, James J. Rucker, Gemma Scott, Ivan Saeger, Francesca Small, Mathieu Seynaeve   +10 more
wiley   +1 more source

Resolving Endoplasmic Reticulum‐Protein Misfolding Restores Corticosteroid Sensitivity in Experimental Models of Severe Asthma

Allergy, EarlyView.
This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake, Alexandra C. Brown, Nikhil T. Awatade, Philip M. Hansbro, Katherine J. Baines, Richard Y. Kim, Nathan W. Bartlett, Jay C. Horvat, Peter A. B. Wark   +8 more
wiley   +1 more source

Development of a nomogram for sperm retrieval at microTESE for idiopathic non‐obstructive azoospermia in a multi‐center cohort study

Andrology, EarlyView.
Abstract Background Non‐obstructive azoospermia (NOA) affects approximately 10% of infertile men and represents a major challenge in assisted reproductive technology (ART). A model that includes histological variants could be helpful in predicting sperm retrieval rate (SRR) after microdissection testicular sperm extraction (mTESE) in patients affected ...
Giorgio Ivan Russo, Edoardo Pozzi, Fausto Negri, Marco Falcone, Emanuele Zupo, Mirko Preto, Maria Giovanna Asmundo, Sandrine Chamayou, Murat Dursun, Ateş Kadıoğlu, Andrea Salonia   +10 more
wiley   +1 more source

Using sleep to enhance exposure treatment for anxious children: A pilot study

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives: Exposure therapy is a well‐established treatment for anxiety disorders in children; however, many young people do not fully respond to treatment. Advances in strategies to enhance extinction learning from exposure therapy are urgently needed.
Ella L. Oar, Ronald M. Rapee, Cassie H. Lavell, Allison G. Harvey, Thomas H. Ollendick   +4 more
wiley   +1 more source

Self‐criticism and dependency in adolescents with depression: Associations with clinical features and psychological functioning

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives The personality dimensions of self‐criticism and dependency have been shown to confer vulnerability to depression, and psychopathology more broadly, in adults. However, evidence for the roles of these personality dimensions in young people is weaker, particularly because most studies in this area have been conducted in non‐clinical ...
Yushi Bai, Nick Midgley, Patrick Luyten
wiley   +1 more source

The tree‐parasitic fungus Cryphonectria carpinicola discovered on European chestnut and European hornbeam in Azerbaijan

EPPO Bulletin, EarlyView.
Abstract The ascomycetous fungus Cryphonectria carpinicola is typically found in its asexual form on the European hornbeam, and its sexual state has only recently been discovered in deadwood of different Carpinus species in Japan. Recently, this fungus has been added to the EPPO Alert List due to its increasing incidence in the EPPO region and a ...
Carolina Cornejo, Dilzara Aghayeva, Ludwig Beenken   +2 more
wiley   +1 more source

Transcriptomic profiling of gill biopsies to define predictive markers for seawater survival in farmed Atlantic salmon

Journal of Fish Biology, EarlyView.
Abstract Wild Atlantic salmon migrate to sea following completion of a developmental process known as parr‐smolt transformation (PST), which establishes a seawater (SW) tolerant phenotype. Effective imitation of this aspect of anadromous life history is a crucial aspect of commercial salmon production, with current industry practice being marred by ...
Lars Grønvold, Mattis J. van Dalum, Anja Striberny, Domniki Manousi, Trine Ytrestøyl, Turid Mørkøre, Solomon Boison, Bjarne Gjerde, Even Jørgensen, Simen R. Sandve, David G. Hazlerigg   +10 more
wiley   +1 more source

Enhanced Risk Stratification of Atrial Fibrillation Detected After Ischemic Stroke and TIA: The Role of Apnoea–Hypopnoea Index and Hypoxic Burden—A Study From the Bern Sleep‐Stroke Registry

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep‐disordered breathing is an independent risk factor for stroke and atrial fibrillation. Accurate assessment of atrial fibrillation in stroke patients with sleep‐disordered breathing is crucial for secondary prevention. This study aimed to determine whether combining apnoea–hypopnoea index and hypoxic burden improves risk stratification ...
Xiaoli Yang, Julian Lippert, Irina Filchenko, Christian M. Horvath, Sebastien Baillieul, Corrado Bernasconi, Stefan A. Bauer‐Gambelli, Anne‐Kathrin Brill, David J. Seiffge, Elias Auer, Tobias Reichlin, Urs Fischer, Marcel Arnold, Markus H. Schmidt, Claudio L. A. Bassetti   +14 more
wiley   +1 more source