Results 221 to 230 of about 71,639 (305)

Effect of carbamazepine on the pharmacokinetics of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader, in healthy adults

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2183-2192, July 2026.
Aim To evaluate the effects of carbamazepine, a strong cytochrome P450 (CYP)3A4 inducer, on the pharmacokinetics and safety of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader. Methods This was a phase 1, open‐label, fixed‐sequence, two‐period study in healthy adult participants.
Hechuan Wang   +7 more
wiley   +1 more source

Cross-species transferability and genetic diversity analysis in Linum species using microsatellite markers. [PDF]

open access: yesSci Rep
Raut VK   +8 more
europepmc   +1 more source

MXenes in Advanced High‐Performance Energy Storage Technologies: Synthesis, Properties, Applications, and Challenges

open access: yesBattery Energy, Volume 5, Issue 4, July 2026.
MXene‐based electrodes are established as high‐performance electrochemical energy storage materials. Sustainable energy storage systems are enabled through biologically derived MXene synthesis routes. Electrochemical kinetics and charge storage are enhanced by biomimetic MXene structures.
Shajjadur Rahman Shajid   +3 more
wiley   +1 more source

α7nAChR agonist GTS‐21 ameliorates sepsis‐induced acute kidney injury via MEF2/PGC‐1α/HO‐1 axis in mice

open access: yesClinical and Translational Medicine, Volume 16, Issue 7, July 2026.
This diagram illustrates opposing pathways regulating AKI (acute kidney injury). The left pathway shows LPS/TLR4 triggering mitochondrial damage (low MMP, Cyt C release, ROS) leading to apoptosis. The right pathway shows α7nAChR agonists activating MEF2 to upregulate PGC‐1α/HO‐1, promoting mitochondrial biogenesis and inhibiting injury, highlighting ...
Yu‐Jia Tang   +15 more
wiley   +1 more source

Socio‐Structural Factors as Predictors of Parents' Intentions to Enrol Their Children in Swimming Lessons

open access: yesHealth Promotion Journal of Australia, Volume 37, Issue 3, July 2026.
ABSTRACT Issue Addressed Swimming lessons are an effective drowning prevention strategy, yet uptake remains socially patterned. Socio‐structural factors such as parent age, sex and family income may shape parents' decisions to enrol their children in swimming lessons.
Kyra Hamilton   +5 more
wiley   +1 more source

Current Evidence of the Effect of Breastfeeding on Ear Molding Outcomes: A Scoping Review

open access: yesThe Laryngoscope, Volume 136, Issue 7, Page 2868-2875, July 2026.
ABSTRACT Objective To provide an overview on auricular molding and to investigate whether breastfeeding is associated with greater cartilage malleability or improved perinatal auricular molding outcomes. Data Sources Embase, MEDLINE, and CENTRAL databases.
Harry Chiang   +5 more
wiley   +1 more source

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