Results 31 to 40 of about 90,859 (300)

Security Sector Reform [PDF]

, 2011
The persistent gap between theory and practice in SSR can be a source of much irritation and disappointment at failures to implement SSR norms as well as in response to concepts and strategies that seem unhelpfully far removed from local realities.
Schnabel, Albrecht, Born, Hans
core   +2 more sources

Axial Function Reflects Global Severity in Inherited Ataxias: The Upright Stability Score in Ambulatory Friedreich vs. Spinocerebellar Ataxia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Inherited ataxias are clinically diverse neurodegenerative diseases, complicating the choice of outcome measures for trials. In spinocerebellar ataxia (SCA), regulatory concerns about the Scale for the Assessment and Rating of Ataxia (SARA) caused a shift toward functional SARA (f‐SARA), contributing to pivotal trial failure.
Christian Rummey, S. H. Subramony, David R. Lynch, Louise A. Corben, Martin B. Delatycki, Jörg B. Schulz, Kathrin Reetz, Massimo Pandolfo, Matthis Synofzik, Theresa Zesiewicz, Antoine Duquette, Matthew Burns, Martin Vyhnálek, Lucie Stovickova, Sinead M. Murphy, Petya Bogdanova‐Mihaylova, Mary Kearney, Richard Walsh, Richard H. Roxburgh, Khalaf Bushara, Marie Y. Davis, Enrico S. Bertini, Gessica Vasco, Shweta Sahni, Mohammed Faruq, Achal K. Srivastava, Bart van de Warrenburg, Elisabetta Indelicato, Sylvia Boesch, Andrew Billnitzer, Tetsuo Ashizawa, Anoopum S. Gupta, Grace Yoon, Georgios Koutsis, Chrysoula Koniari, Zofia Fleszar, Christopher M. Gomez, Andrea Martinuzzi, Gabriella Paparella, Ali G. Hamedani, Puneet Opal, Rizwan S. Akhtar, Caterina Mariotti, Henry Paulson, Peter Todd, Sharan R. Srinivasan, George Wilmot, Ludger Schöls, Susan Perlman, Jeremy D. Schmahmann, Sheng‐Han Kuo, Liana S. Rosenthal, Vikram G. Shakkottai   +52 more
wiley   +1 more source

An Integrated Oxygen‐Supplying Device and Predictive Multiphysics Model for Extended Ambient Transport of Insulin‐Producing Cells

Advanced Functional Materials, EarlyView.
Cell therapies typically rely on cold‐chain logistics and cryopreservation, limiting access and compromising cell quality. Here, a dual‐chamber device separates an oxygen‐supplying chamber from a hyaluronic acid cargo chamber, sustaining oxygen delivery for over 70 h and enabling ambient‐temperature shipment.
Daniel A. Domingo‐Lopez, Ruth Tarpey, Benjamin Brennan, Bryan D. Boyle, Amir M. Alsharabasy, Abhik Mallick, Gabriella Bellavia, Abhay Pandit, Garry P. Duffy, Ruth E. Levey   +9 more
wiley   +1 more source

Green bioanalytical method development and validation for estimation of Imeglimin hydrochloride using human plasma in pure form by LC–MS/MS

Future Journal of Pharmaceutical Sciences
Background A bioanalytical method was developed and validated in accordance with US FDA guidelines for estimating Imeglimin hydrochloride levels in human plasma using liquid chromatography with mass spectrometry (LC–MS/MS).
Chandni V. Chandarana, Vidhi H. Vashi, Anjana Bera, Jaiminkumar Patel   +3 more
doaj   +1 more source

Management of Bleeding in Extrahepatic Portal Venous Obstruction

International Journal of Hepatology, 2013
Extrahepatic portal venous obstruction, although rare in the western world, is a common cause of major and life threatening upper gastrointestinal bleeding among the poor in developing countries. Patients have large spleens and stunted growth.
N. Chaudhary, S. Mehrotra, M. Srivastava, S. Nundy   +3 more
doaj   +1 more source

Development and Characterization of SSR Markers via de Novo Transcriptome Assembly in Apocynum. hendersonii

Journal of Natural Fibers, 2023
To provide a theoretical and practical foundation for the genetic analysis of Apocynum species, SSRs were identified based on the transcriptomic data of A.hendersonii leaves. A total of 50,957 unigenes containing 5 660 SSR motifs with an average of 1 SSR
Gang Gao, Chunming Yu, Jikang Chen, Kunmei Chen, Xiaofei Wang, Aiguo Zhu, Ping Chen   +6 more
doaj   +1 more source

SSR-data

, 2018
Data from 15 SSR loci for the 484 Malus accessions included in Larsen et al.
Myles, Sean, Gardner, Kyle, Marian Ørgaard (5635151), Toldam-Andersen, Torben Bo, Kyle Gardner (2808238), Torben Bo Toldam-Andersen (5635154), Zoë Migicovsky (2808235), Sean Myles (47114), Larsen, Bjarne, Migicovsky, Zoë, Ørgaard, Marian, Bjarne Larsen (5635148), Pedersen, Carsten, Carsten Pedersen (258350)   +13 more
core   +1 more source

A high-density consensus map of barley linking DArT markers to SSR, RFLP and STS loci and agricultural traits [PDF]

, 2006
Background: Molecular marker technologies are undergoing a transition from largely serial assays measuring DNA fragment sizes to hybridization-based technologies with high multiplexing levels.
Wenzl Peter, Haobing Li, Harsh Raman, Andris Kleinhofs, Huttner, E., Xia Ling, Zhou, M., Wang, J., Hearnden, P., Zhou Meixue, Meixue Zhou, Chalmers, K.J., Paul, E., Ovesná, J., Smith, K., Li Haobing, Muehlbauer Gary J, Caig, V., Huttner Eric, Hearnden Phillippa, Chalmers Ken J, Kleinhofs Andris, Smith Kevin P, Jaroslava Ovesná, Kevin P Smith, Andrzej Kilian, Muehlbauer, G., Rosy Raman, et al., Chalmers, K., Gary J Muehlbauer, Kilian, A., Carling, J., Ken J Chalmers, Paul Edie, David Poulsen, Kilian Andrzej, Raman, R., Junping Wang, Poulsen David, Edie Paul, Phillippa Hearnden, Carling Jason, Peter Wenzl, Ling Xia, Ovesná Jaroslava, Eric Huttner, Wang Junping, Maier Christina, Kleinhofs, A., Mehmet Cakir, Raman, H., Cakir Mehmet, Maier, C., Raman Harsh, Smith, K.P., Muehlbauer, G.J., Caig Vanessa, Jason Carling, Christina Maier, Cakir, M., Raman Rosy, Xia, L., Poulsen, D., Li, H., Vanessa Caig, Wenzl, P., Plant Science   +67 more
core   +2 more sources

Early Spatial and Contextual Coding Deficits in Hippocampal CA1 Precede Performance Decline in an Alzheimer's Disease Model

Advanced Science, EarlyView.
Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li, Mary Ann Go, Hualong Zhang, Robertas Aleksynas, Juliana Kim, Mingyang Gao, Seigfred Prado, Magdalena Sastre, Simon R. Schultz   +8 more
wiley   +1 more source

Security Sector Reform and Citizen Security [PDF]

, 2019
While widely considered a core pillar of the peace and security architecture, Security Sector Reform (SSR) is coming under fire. SSR theory and practice are criticized for being overly focused on traditional conflict and post-conflict settings and for ...
de Boer, John, Muggah, Robert
core   +3 more sources