Results 91 to 100 of about 30,543 (245)

Association Between SGLT2 Inhibitors and DPP‐4 Inhibitors Use and Risk of Acute Pancreatitis: Findings From Nationwide Case‐Based Analyses

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims The Korean national health insurance claims database was utilised to investigate the association between sodium–glucose cotransporter 2 inhibitors (SGLT2i) or dipeptidyl peptidase‐4 inhibitors (DPP‐4i) and the risk of acute pancreatitis (AP). Materials and Methods Patients with type 2 diabetes mellitus prescribed DPP‐4i or SGLT2i at least
Ye‐Jee Kim   +5 more
wiley   +1 more source

Mental Health Disorders in End‐Stage Kidney Disease: A Narrative Review of Clinical Considerations for Integrated Management

open access: yesHemodialysis International, EarlyView.
ABSTRACT Introduction End stage kidney disease (ESKD) is associated with a high prevalence of depression and anxiety, arising from both biological factors and the psychosocial burden of chronic dialysis care. Approximately 25%–30% of dialysis patients experience clinically significant depressive symptoms when assessed by structured clinical interview ...
Kunal Malhotra   +2 more
wiley   +1 more source

Swiss Practice Recommendations for Chronic Prurigo Including Prurigo Nodularis

open access: yesInternational Journal of Dermatology, EarlyView.
Chronic prurigo, including prurigo nodularis, is a chronic, often treatment‐refractory condition characterized by persistent pruritus and chronic scratch lesions. Advances in the understanding of its underlying pathophysiology have enabled the development of novel targeted therapies; however, management remains challenging due to the expanding range of
Simon M. Mueller   +11 more
wiley   +1 more source

Influence of SSRI and SNRI co-prescription on benzodiazepine prescription trajectories

open access: yesDrug and Alcohol Dependence Reports
Purpose: This study examined whether co-prescription of selective serotonin reuptake inhibitors (SSRIs) or serotonin or norepinephrine reuptake inhibitors (SNRI)s with benzodiazepines is associated with differences in benzodiazepine prescriptions both ...
Kerry L. Kinney   +4 more
doaj   +1 more source

Cannabidiol, a promising therapy for post-traumatic stress disorder and depression. A mini-review

open access: yesActa Marisiensis - Seria Medica
Post-traumatic stress disorder (PTSD) is a mental health disorder, manifesting in people who have endured traumatic events like violence, war, natural disasters, accidents, or other life-threatening situations.
Jîtcă George
doaj   +1 more source

Substitution Patterns After Discontinuation of CNS‐Active Medications in Older Adults in Primary Care

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Little is known about substitution of alternative medications in the context of deprescribing. The objectives were to: (1) determine the frequency of medication substitutions among those who discontinued a central nervous system (CNS)‐active medication, and (2) characterize substitutions as potentially inappropriate (as per the 2023
Shelly L. Gray   +6 more
wiley   +1 more source

Social cognition in children and adolescents with fragile X syndrome: A comparison with individuals with autism symptoms and typical development

open access: yesJournal of Neuropsychology, EarlyView.
Abstract Most individuals with fragile X syndrome (FXS) exhibit symptoms of autism spectrum disorder (ASD), suggesting a substantial overlap in social cognitive profiles. This cross‐sectional study aimed to explore social cognitive abilities in children and adolescents with FXS in comparison with an age‐matched heterogeneous ASD group and typically ...
Kamil R. Hiralal   +8 more
wiley   +1 more source

CHARGE Syndrome: A Narrative Review and Update on Diagnosis, Assessment and Management

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background CHARGE syndrome (CS) is a rare multisystemic genetic condition caused by a pathogenic variant in the DNA‐binding protein‐7 CHD7 gene. The condition affects the development of neural crest cells, which give rise to craniofacial structures, cranial nerves, ears, eyes and the heart, resulting in diverse and complex clinical features ...
Eleni M. van Gelder   +7 more
wiley   +1 more source

Phenotypic Variability in Slow‐Wave Sleep in Depression: Associations With Clinical Profiles and Disorder Severity

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Slow‐wave sleep (SWS; stage N3) is often reported as reduced in depression, yet variability across depressive phenotypes remains poorly characterised. This study aimed to determine whether N3 architecture—proportion, duration, and latency—identifies clinically distinct profiles in major depressive episode (MDE).
Antoine Salmeron   +8 more
wiley   +1 more source

Psychophysiological indicators of emotional arousal in sexual assault survivors: Evaluating ANS reactivity to therapeutic COPE cards within the SEE FAR CBT framework for PTSD treatment

open access: yesPsychology and Psychotherapy: Theory, Research and Practice, EarlyView.
Abstract Objective SEE FAR CBT is an integrative treatment protocol for PTSD and anxiety disorders, utilizing imagery‐based (fantastic reality) methods through associative therapeutic COPE cards. Although preliminary evidence suggests potential impacts, further validation is necessary to confirm their efficacy in eliciting specific arousal‐affective ...
Sivan Raz, Noa Burchis, Mooli Lahad
wiley   +1 more source

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