Serotonin reuptake inhibitors (SSRIs), along with serotonin norepinephrine reuptake inhibitors (SNRIs) and norepinephrine dopamine reuptake inhibitors (NDRIs), are the first-line drugs in the treatment of depression.
Ewa Krzewicka-Romaniuk +2 more
doaj +1 more source
Concomitant medication use and clinical outcome of repetitive Transcranial Magnetic Stimulation (rTMS) treatment of Major Depressive Disorder. [PDF]
BackgroundRepetitive Transcranial Magnetic Stimulation (rTMS) is commonly administered to Major Depressive Disorder (MDD) patients taking psychotropic medications, yet the effects on treatment outcomes remain unknown.
Chawla, Shweta A +7 more
core +1 more source
An n‐of‐1 gene‐directed drug repurposing trial for an ultrarare genetic condition
Abstract Objective Gain‐of‐function (GoF) variants in the KCNC1 potassium channel subunit gene (Kv3.1) cause motor/cognitive delays and hypotonia and have been associated with seizures. Fluoxetine has inhibitory effects on Kv3.1. However, open‐label nonrandomized administration is insufficient to guide clinical decision‐making in ultrarare conditions ...
Vedika Jha +13 more
wiley +1 more source
Depression in the elderly as a significant clinical problem
Introduction: Depression is a very common mental disorder among older people. It limits life activity and interests. It causes difficulties in making decisions or actions.
Eliza Niewiadomska +5 more
doaj +1 more source
Maternal methadone use in pregnancy : factors associated with the development of neonatal abstinence syndrome and implications for healthcare resources [PDF]
The objectives of this study were to investigate factors associated with the development of neonatal abstinence syndrome (NAS) and to assess the implications for healthcare resources of infants born to drug-misusing women. Design.
Dryden, C. +3 more
core +1 more source
ABSTRACT Introduction Adolescents with anorexia nervosa (AN) often present cognitive rigidity, impaired decision‐making, and difficulties processing emotions, all of which can impede engagement in treatment. The marked rise in paediatric hospitalisations for AN during the COVID‐19 pandemic highlights the urgent need for brief, targeted interventions in
Dario Marin +4 more
wiley +1 more source
Fluoxetine brakes the menstrual cycle: Uncovering the unexpected effect
Fluoxetine is one of the most commonly used antidepressants, classified under selective serotonin reuptake inhibitors (SSRIs). It is indicated for the treatment of depression, obsessive-compulsive disorder, anxiety, and eating disorders.
Barath Ramanathan +3 more
doaj +1 more source
Probability in the Everett World: Comments on Wallace and Greaves [PDF]
It is often objected that the Everett interpretation of QM cannot make sense of quantum probabilities, in one or both of two ways: either it can't make sense of probability at all, or it can't explain why probability should be governed by the Born rule ...
Price, Huw
core +1 more source
Selective Serotonin Reuptake Inhibitor Antidepressant Treatment Discontinuation Syndrome: A Review of the Clinical Evidence and the Possible Mechanisms Involved [PDF]
Besides demonstrated efficacy, selective serotonin reuptake inhibitors (SSRIs) hold other advantages over earlier antidepressants such as greater tolerability and a wider range of clinical applications.
Thibault Renoir
core +2 more sources
Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley +1 more source

