Results 51 to 60 of about 40,743 (286)

Simulation of crack growth life in the skin elements of aviation constructions under variable-amplitude loading

open access: yesНаучный вестник МГТУ ГА, 2016
The paper shows possibility to use Paris-Erdogan equation for simulation of fatigue crack growth under random loading. In the considered equation effective stress intensity factor range was introduced.
V. V. Nikonov, V. S. Shapkin
doaj  

Suprathreshold dosing of selective serotonin reuptake inhibitors in treatment-resistant obsessive-compulsive disorder: A case series

open access: yesIndian Journal of Psychiatry
Supratherapeutic dosing of selective serotonin reuptake inhibitors (SSRIs) in obsessive-compulsive disorder (OCD) is an area of clinical interest, particularly for treatment-resistant cases.
Indranil Saha   +4 more
doaj   +1 more source

Secondary and side effects of particular Selective Serotonin Reuptake Inhibitors (SSRIs) antidepressants - literature review

open access: yesJournal of Education, Health and Sport, 2020
Serotonin reuptake inhibitors (SSRIs), along with serotonin norepinephrine reuptake inhibitors (SNRIs) and norepinephrine dopamine reuptake inhibitors (NDRIs), are the first-line drugs in the treatment of depression.
Ewa Krzewicka-Romaniuk   +2 more
doaj   +1 more source

SSRI Safety During Pregnancy [PDF]

open access: yes, 2012
Depression is one of the most common disorders in our country today. The most frequently used treatment for depression is the antidepressant drug class, selective serotonin reuptake inhibitors (SSRis).
Johnson, Julie N
core   +1 more source

Clozapine:norclozapine ratio as a marker of metabolic risk and therapeutic response and effect of valproate on clozapine levels

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Clozapine is the most effective antipsychotic in treatment‐resistant schizophrenia. Clozapine causes weight gain and increased diabetes risk. The role of its metabolite norclozapine and clozapine:norclozapine ratio (CLZ/NCLZ) in metabolic effects has been debated.
Susanna Maria Rask   +6 more
wiley   +1 more source

The linear model using in crack growth simulation under variable-amplitude loading

open access: yesНаучный вестник МГТУ ГА, 2016
The paper shows the possibility of using Paris-Erdogan equation for simulation fatigue crack growth under random loading. The considered equation has introduced the effective stress intensity factor range.
V. V. Nikonov, V. S. Shapkin
doaj  

Exposure to CYP2C19‐metabolized drugs following acute stroke: A longitudinal cohort study to inform implementation of CYP2C19 genotype testing

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Cytochrome P450 2C19 (CYP2C19) genotype testing is recommended to guide antiplatelet selection after ischaemic stroke and transient ischaemic attack. CYP2C19 also metabolizes several commonly prescribed non‐antiplatelet drugs. We aimed to quantify exposure to CYP2C19‐metabolized drugs in stroke patients at hospital discharge and during ...
Cleodie C. Swire   +3 more
wiley   +1 more source

Psychological and sexual functioning of persons suffering from post-SSRI sexual dysfunction – cases study

open access: yes
Background Post-SSRI syndrome is a condition following the discontinuation of selective serotonin reuptake inhibitors (SSRIs) where, despite ceasing to take the pharmacological agents, the effects persist – and they may develop upon drug initiation ...
Kacper Gargul   +1 more
core   +1 more source

Environmental impact of antidepressants: Is a new prescription framework possible?

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Antidepressants such as venlafaxine and sertraline pose high risks to water ecosystems. As depressive disorders and other mental health conditions become increasingly prevalent worldwide, prescription and environmental presence of these pharmaceuticals continue to rise. This study explores the practical viability of a new framework for prescribing
Matilde Bianconi   +5 more
wiley   +1 more source

Depression in the elderly as a significant clinical problem

open access: yesJournal of Education, Health and Sport, 2019
Introduction: Depression is a very common mental disorder among older people. It limits life activity and interests. It causes difficulties in making decisions or actions.
Eliza Niewiadomska   +5 more
doaj   +1 more source

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