Clinical Characteristics of PMS Co-Morbid with MDD and Effectiveness of SSRIs in its Treatment
Background: Data on the clinical characteristics of premenstrual syndrome (PMS) with co-morbid major depressive disorder (MDD) are scarce. Although selective serotonin re-uptake inhibitors (SSRIs) are widely used to treat both PMS and MDD there is little
Yakimova R. +4 more
doaj +1 more source
Fluoxetine Prevents the Development of Depressive-like Behavior in a Mouse Model of Cancer Related Fatigue [PDF]
Cancer patients frequently suffer from fatigue, a complex syndrome associated with tiredness and depressed mood. Cancer-related fatigue (CRF) can be present at the time of diagnosis, escalates during treatment, and can persist for years after treatment ...
Bicer, Sabahattin +7 more
core +2 more sources
Maternal fluoxetine exposure alters cortical hemodynamic and calcium response of offspring to somatosensory stimuli [PDF]
Epidemiological studies have found an increased incidence of neurodevelopmental disorders in populations prenatally exposed to selective serotonin reuptake inhibitors (SSRIs).
Brier, Lindsey M +4 more
core +1 more source
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley +1 more source
Profiling placental DNA methylation associated with maternal SSRI treatment during pregnancy
Selective serotonin reuptake inhibitors (SSRIs) for treatment of prenatal maternal depression have been associated with neonatal neurobehavioral disturbances, though the molecular mechanisms remain poorly understood.
Amy M. Inkster +12 more
doaj +1 more source
Adverse Drug Events on the Use of Sertraline in Clinical Studies: A Review
Major depressive disorder (MDD) and anxiety are known as a widespread public health problem treated with sertraline, a class of Selective Serotonin Reuptake Inhibitor (SSRI) drugs as first-line therapy.
Syahrul Hidayat, Irma M. Puspitasari
doaj +1 more source
Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery. [PDF]
BACKGROUND: Stroke is the major cause of adult disability. Selective serotonin reuptake inhibitors (SSRIs) have been used for many years to manage depression.
Anne Claxton +6 more
core +1 more source
The 3‐Hit Metabolic Signaling Model for Autism Spectrum Disorder: A Summary
ABSTRACT Autism spectrum disorder (ASD) is a highly heritable yet environmentally sensitive neurodevelopmental condition whose biological heterogeneity has resisted a unifying causal explanation for over 100 years. The 3‐hit metabolic signaling model proposes that ASD arises from abnormal persistence of an evolutionarily conserved stress‐response ...
Robert K. Naviaux
wiley +1 more source
Examining the reversibility of long-term behavioral disruptions in progeny of maternal SSRI exposure [PDF]
Serotonergic dysregulation is implicated in numerous psychiatric disorders. Serotonin plays widespread trophic roles during neurodevelopment; thus perturbations to this system during development may increase risk for neurodevelopmental disorders ...
Akula, Shyam +7 more
core +1 more source
ABSTRACT Cortical thickness (CT) differences between autistic individuals (AI) and neurotypical controls have been consistently reported, yet the neurochemical mechanisms underlying these differences remain insufficiently understood. Neurotransmitter receptor systems exhibit distinct spatial distributions across the cortex and influence synaptic ...
Livio Tarchi +9 more
wiley +1 more source

