Results 41 to 50 of about 30,543 (245)

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source

Secondary and side effects of particular Selective Serotonin Reuptake Inhibitors (SSRIs) antidepressants - literature review

Journal of Education, Health and Sport, 2020
Serotonin reuptake inhibitors (SSRIs), along with serotonin norepinephrine reuptake inhibitors (SNRIs) and norepinephrine dopamine reuptake inhibitors (NDRIs), are the first-line drugs in the treatment of depression.
Ewa Krzewicka-Romaniuk, Dagna Siedlecka, Artur Romaniuk   +2 more
doaj   +1 more source

The linear model using in crack growth simulation under variable-amplitude loading

Научный вестник МГТУ ГА, 2016
The paper shows the possibility of using Paris-Erdogan equation for simulation fatigue crack growth under random loading. The considered equation has introduced the effective stress intensity factor range.
V. V. Nikonov, V. S. Shapkin
doaj  

Comparison of the groups treated with mirtazapine and selective serotonine reuptake inhibitors with respect to birth outcomes and severity of psychiatric disorder

Psychiatry and Clinical Psychopharmacology, 2019
Objective: The literature provides very limited information on mirtazapine usage in the pregnancy period. The groups including pregnant women who used SSRI or mirtazapine as a single treatment, SSRI–mirtazapine combination treatment and unmedicated ...
Buket Belkız Güngör, Nalan Öztürk, Ayça Öngel Atar, Nazan Aydın   +3 more
doaj   +1 more source

Associations Between Microbial Depletion and Autonomic Dysregulation in Binge‐Eating Disorder

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective The interplay between the gut microbiome and autonomic nervous system remains unexplored in binge‐eating disorder (BED). We aimed to explore specific microbial alterations in BED and examine their potential association with cardiac vagal tone as a distinct bio‐behavioral phenotype.
Shuang Liang, Esben Strodl, Leanne Barron, Matthew Bambling, Luis Vitetta   +4 more
wiley   +1 more source

Sexual dysfunctions, depression and antidepressants

Psychiatry and Behavioral Sciences, 2011
Normal sexual function is a biopsychosocial process; sexual problems almost always has organic and psychological components and requires multidisciplinary evaluation and treatment.
Sultan Doğan
doaj   +1 more source

An n‐of‐1 gene‐directed drug repurposing trial for an ultrarare genetic condition

Epilepsia, EarlyView.
Abstract Objective Gain‐of‐function (GoF) variants in the KCNC1 potassium channel subunit gene (Kv3.1) cause motor/cognitive delays and hypotonia and have been associated with seizures. Fluoxetine has inhibitory effects on Kv3.1. However, open‐label nonrandomized administration is insufficient to guide clinical decision‐making in ultrarare conditions ...
Vedika Jha, Christina Tsetsos, Mark Bedford, Gregory Costain, Sunita Vohra, Juan Pablo Diaz Martinez, Elise Heon, Jacob Vorstman, Carolina Gorodetsky, Ajoy Vincent, Jesiqua Rapley, Lori Anderson, Evdokia Anagnostou, Danielle A. Baribeau   +13 more
wiley   +1 more source

Effects of SSRI medication on heart rate and blood pressure in individuals with hypertension and depression

Clinical and Experimental Hypertension, 2019
Objective: To test the role of escitalopram on blood pressure and heart rate of individuals with hypertension and depression. Methods: A total of 30 individuals participated in this study who were being treated for hypertension and were diagnosed with ...
MF Peixoto, MLR Cesaretti, SD Hood, A Tavares   +3 more
doaj   +1 more source

SSRI Induced Apathy Syndrome

Psychiatry and Behavioral Sciences, 2018
Objective: Apathy is defined as diminished motivation and reduced goal-directed behavior accompanied by decreased emotional responsiveness. Besides being a symptom of some neurological conditions and psychiatric disorders, apathy is also a known to be an
Elcin Ozsin Aydemir, Eda Aslan, Mustafa Kemal Yazici   +2 more
doaj   +1 more source

Resumption of Menses and Normalisation of Body Weight in Adolescents Undergoing Specialised Treatment for Anorexia Nervosa Inpatient or Outpatient Treatment

European Eating Disorders Review, EarlyView.
ABSTRACT Objective To predict resumption of menses (ROM) in patients with anorexia nervosa (AN). Method Females aged 9–17 years with AN, receiving inpatient multimodal treatment (IMT) or family‐based treatment (FBT) underwent assessments at baseline, 6‐month and 12‐month follow‐up (12FU).
Annika Woltmann, Linus Imken, Vivien Kaiser, Johanna L. Keeler, Daniel Le Grange, Christoph U. Correll, Verena Haas   +6 more
wiley   +1 more source