Results 161 to 170 of about 64,955 (305)

Physiological and anatomical determinants of placental drug transfer

The Journal of Physiology, EarlyView.
Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis, Anandita Umapathy, Jane K. Cleal, Bram G. Sengers   +3 more
wiley   +1 more source

Serotonergic antidepressants are associated with increased bleeding events within 30-days after total shoulder arthroplasty: a propensity-matched analysis of 54,291 patients. [PDF]

Arch Orthop Trauma Surg
Strony JT, Moyal AJ, Adelstein JM, Burkhart RJ, Imbrogno AM, Abid R, Gillespie RJ, Chen RE.   +7 more
europepmc   +1 more source

Modulation of pain by affective touch: effects of childhood trauma, depression, chronic pain, and spinal segment

The Journal of Physiology, EarlyView.
Abstract figure legend Patients with fibromyalgia and no‐pain controls completed questionnaire ratings of chronic pain, childhood trauma, anxiety and depression. During the first session a conditioned pain modulation task was administered, with heat pain applied via thermode and cold pain via cold water‐bath.
Benedetta Albinni, Marisa Zimmerman, Vincent Alasha, Jacob Ross, Lindsey Crankshaw, Emrys Jones, Jeffery Lewis, Sandy R. Hu, Nathaniel Schuster, Laura Case   +9 more
wiley   +1 more source

Managing anxiety-related disorders from pregnancy to parenthood. [PDF]

Arch Gynecol Obstet
Scholten W, Saris I, Eigenhuis E, de Koning L, Muntingh A, Schut B, Seldenrijk A, van Oppen P, Batelaan N.   +8 more
europepmc   +1 more source

Real Output in Mental Health Care During the 1990s [PDF]

Health accounts document changes over time in the level and composition of health spending. There has been a continued evolution in the ability to track such outlays. Less rapid has been the ability to interpret changes in spending.
Alisa B. Busch, Ernst R. Berndt, Richard G. Frank, Sharon-Lise Normand   +3 more
core  

Distinct effects of fibromyalgia pain, depression and anxiety on perception of affective touch and pain

The Journal of Physiology, EarlyView.
Abstract figure legend Patients with fibromyalgia (FM) and no‐pain controls completed questionnaire‐based ratings of chronic pain, childhood trauma, anxiety and depression. Brief touch stimuli were then administered, including slow brushing at the C‐tactile optimal velocity of 3 cm/s, deep oscillating pressure with a compression sleeve, roboticized ...
Benedetta Albinni, Marisa Zimmerman, Vincent Alasha, Jacob Ross, Lindsey Crankshaw, Sandy R. Hu, Nathaniel Schuster, Laura Case   +7 more
wiley   +1 more source

Antidepressant Use and Risk of Reoperation After Distal Radius Open Reduction and Internal Fixation: A Propensity Score-Matched Cohort Study. [PDF]

J Hand Surg Glob Online
Kurbanov F, Dussik C, Phan A, Rouege Z, Wilbur D, Ketonis C.   +5 more
europepmc   +1 more source

Implementation of OMOP and ConcePTION Common Data Models in CPRD GOLD: Risk of Bleeding and Cardiovascular Outcomes From Anticoagulant Use

Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1574-1583, June 2026.
The impact of the choice of common data model (CDM) approach on the study results in a real‐world evidence (RWE) study is unknown. We aimed to determine potential differences in the results of an RWE study when data were mapped to two different CDMs, ConcePTION and OMOP. With the same instance of CPRD GOLD, data were mapped to both CDMs. Using the same
Nicholas B. Hunt, Patrick Souverein, Marloes Bazelier, Nicola Barclay, Antonella Delmestri, Miriam Sturkenboom, Daniel Prieto‐Alhambra, Helga Gardarsdottir, Olaf Klungel   +8 more
wiley   +1 more source

Pharmacological treatment of obsessive-compulsive disorder in children and adolescents: An overview. [PDF]

World J Clin Pediatr
Rajalakshmi AK, Pawar AKS, Baweja R.
europepmc   +1 more source

Serum Amyloid β Oligomer May Predict Treatment Response in Middle‐Aged and Late‐Life Patients With Depression

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
After 4 weeks of antidepressant treatment, patients with serum amyloid β oligomers showed a significantly lower treatment response compared with those without Aβ oligomers among middle‐aged and late‐life patients with major depressive disorder. ABSTRACT Aim Late‐life patients with depression are reportedly less responsive to antidepressant treatment ...
Kentaro Shimizu, Seita Yasuda, Hitoshi Maeshima, Tomoya Ichikawa, Hajime Baba   +4 more
wiley   +1 more source