Results 51 to 60 of about 4,889 (179)

Global impact of somatic structural variation on the DNA methylome of human cancers

Genome Biology, 2019
Background Genomic rearrangements exert a heavy influence on the molecular landscape of cancer. New analytical approaches integrating somatic structural variants (SSVs) with altered gene features represent a framework by which we can assign global ...
Yiqun Zhang, Lixing Yang, Melanie Kucherlapati, Angela Hadjipanayis, Angeliki Pantazi, Christopher A. Bristow, Eunjung Alice Lee, Harshad S. Mahadeshwar, Jiabin Tang, Jianhua Zhang, Sahil Seth, Semin Lee, Xiaojia Ren, Xingzhi Song, Huandong Sun, Jonathan Seidman, Lovelace J. Luquette, Ruibin Xi, Lynda Chin, Alexei Protopopov, Peter J. Park, Raju Kucherlapati, Chad J. Creighton   +22 more
doaj   +1 more source

Arthroscopic Partial Repair and Arthroscopic Debridement Improve Pain and Functional Outcomes in Older Patients With Massive Irreparable Rotator Cuff Tears: A Systematic Review

Arthroscopy, Sports Medicine, and Rehabilitation, Volume 8, Issue 4, August 2026.
Purpose To evaluate the current evidence on patient‐reported outcomes and complications after arthroscopic partial repair and arthroscopic debridement for massive irreparable rotator cuff tears (MIRCTs) in patients aged 65 years or older. Methods A systematic search of MEDLINE, Embase, and Cochrane Library databases was conducted through September 2025
Dave Osinachukwu Duru, Andrew Kailin Zhou, Rahul Geetala, Andrew Metcalfe, Salma Chaudhury   +4 more
wiley   +1 more source

The Effects of High‐ and Moderate‐Intensity Exercise on Epithelial Integrity Markers and Inflammatory Responses in Healthy Young Men

European Journal of Sport Science, Volume 26, Issue 8, August 2026.
ABSTRACT The effects of exercise intensity on airway epithelial integrity markers and inflammatory responses remain unknown. Therefore, we investigated the effects of high‐ and moderate‐intensity exercise on airway epithelial integrity markers (club cell protein 16 [CC16], surfactant protein D [SP‐D], and the CC16/SP‐D ratio), along with systemic ...
Saeid Nikoukheslat, Hadi Pourmanaf, Vahid Sari‐Sarraf, Ramin Amirsasan, Dean E. Mills   +4 more
wiley   +1 more source

Mechanical Behavior Simulation and Performance Curve Investigation of Subsurface Safety Valves

Shiyou jixie, 2023
To eliminate potential hazards caused by the changes in wellbore mechanical behaviors, it is necessary to investigate the performance of subsurface safety valves(SSVs)under different working conditions.Taking the 31/2' SP SSV commonly used in oilfields
Zhu Shuai, Wang Zhiyong, Jiang Liping, Nan Huanghe, Li Mingfei, Dou Yihua   +5 more
doaj  

A Novel Small‐Molecule Dual Adiponectin Receptor 1/2 Agonist Induces Myogenesis and Ameliorates Skeletal Muscle Atrophy

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Skeletal muscle atrophy is a hallmark of ageing and chronic diseases, yet effective pharmacotherapies remain unavailable. Adiponectin signalling through AdipoR1 and AdipoR2 regulates skeletal muscle metabolism, regeneration and oxidative capacity, but the therapeutic use of adiponectin is limited by its large size and complex ...
Shubhrajyoti Das, Pallavi Awasthi, Md. Rameez Moin, Shyamal Pal, Anushka Talukdar, Akhilesh Kumar, Nikhil Nikolas, Shruti Suhas Varode, Shamima Khatoon, Nabanita Das, Sourav Chattopadhyay, Madhav Nilkanth Mugale, Rajdeep Guha, Sabyasachi Sanyal, Atul Goel   +14 more
wiley   +1 more source

Advanced Characterization of DNA Molecules in rAAV Vector Preparations by Single-stranded Virus Next-generation Sequencing

Molecular Therapy: Nucleic Acids, 2015
Recent successful clinical trials with recombinant adeno-associated viral vectors (rAAVs) have led to a renewed interest in gene therapy. However, despite extensive developments to improve vector-manufacturing processes, undesirable DNA contaminants in ...
Emilie Lecomte, Benoît Tournaire, Benjamin Cogné, Jean-Baptiste Dupont, Pierre Lindenbaum, Mélanie Martin-Fontaine, Frédéric Broucque, Cécile Robin, Matthias Hebben, Otto-Wilhelm Merten, Véronique Blouin, Achille François, Richard Redon, Philippe Moullier, Adrien Léger   +14 more
doaj   +1 more source

Image Watermarking Scheme Based on DWT-DCT and SSV

International Journal of Security and Its Applications, 2016
With the fast development of network, it becomes urgent to protect copyright and rightful ownership of an image, and digital watermark technology is a comprising solution to do that. However, the false positive problem exists in a number of watermarking schemes based on singular value decomposition (SVD).
Zhi Zhang, Chengyou Wang, Xiao Zhou
openaire   +1 more source

Sustainable and Antistatic Nanocomposites Based on Poly(Lactic Acid) (PLA): Effect of the Green Plasticizer and Plasma‐Functionalized Carbon Nanotubes

Polymers for Advanced Technologies, Volume 37, Issue 8, August 2026.
ABSTRACT Conductive and sustainable polymer nanocomposites combine functional performance with environmental responsibility. In this study, flexible and sustainable nanocomposites based on poly(lactic acid) (PLA), epoxidized soybean oil (ESO), and carbon nanotubes (MWCNT), before and after oxygen plasma functionalization (MWCNTf), were developed by ...
Flávio Urbano da Silva, Carlos Bruno Barreto Luna, Eduardo da Silva Barbosa Ferreira, Fabiano Santana da Silva, Valmar da Silva Severiano Sobrinho, Thércio Henrique de Carvalho Costa, Renate Maria Ramos Wellen, Edcleide Maria Araújo   +7 more
wiley   +1 more source

Disentangling Internal Tides From Balanced Motions With Deep Learning and Surface Field Synergy

Journal of Advances in Modeling Earth Systems, Volume 18, Issue 8, August 2026.
Abstract A fundamental challenge in ocean dynamics is disentangling balanced motions and internal waves. Extracting internal tidal (IT) imprints from surface data is a central part of this challenge. Traditional harmonic analysis fails under strong incoherence and poor temporal sampling, as in global satellite observations.
Han Wang, Jeffrey Uncu, Kaushik Srinivasan, Nicolas Grisouard   +3 more
wiley   +1 more source

Mesopic microperimetry in Stargardt disease: Application and reliability

Acta Ophthalmologica, Volume 104, Issue 5, Page e544-e554, August 2026.
Abstract Purpose Mesopic microperimetry (mMP) is a promising functional endpoint in clinical trials for Stargardt disease type 1 (STGD1). This study evaluated the test–retest variability of mMP and influencing factors, which is essential for ensuring reliability in future STGD1 trials.
Sybren H. Kootstra, Jeroen A. A. H. Pas, Patty P. A. Dhooge, Steffen Schmitz‐Valckenberg, Maurizio Battaglia Parodi, Philipp Herrmann, Frank G. Holz, Andrew J. Lotery, Katarina Stingl, Thomas H. Wheeler‐Schilling, Camiel J. F. Boon, Carel B. Hoyng, Soraprazan Consortium   +12 more
wiley   +1 more source