Remodeling of Metabolic and Secretory Organelles During Oncogenic and Oncomodulatory Viral Infections [PDF]
VirusesPersistent oncovirus infections account for 15–20% of the global cancer burden, driving multiple forms of human cancer. To maintain persistent infection and spread, oncoviruses drive alterations in host cell metabolism, immune signaling, and cell-to-cell
William Rodriguez, Ileana M. Cristea
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Hepatitis virus-associated B cell non-Hodgkin’s lymphoma involves dysregulated epigenetic and RNA-mediated regulatory gene expression and altered snoRNA transcription [PDF]
Scientific ReportsInfection with HBV and its satellite virus HDV remain a significant global health issue due to their involvement in hepatic and extrahepatic diseases, including B cell non-Hodgkin’s lymphoma (BNHL).
Amanda N. Henning +15 more
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The effect of virus-induced cellular transformation on oncogenesis [PDF]
Наука и инновации в медицине, 2023 Aim to summarize the scientific data presented in the recent publications on tumor-associated processes induced by viruses. We analyzed 23 international publications devoted to the development and course of tumor-related processes associated with ...
Aleksandr V. Moskalev +3 more
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Dendrosomal nanocurcumin prevents EBV-associated cell transformation by targeting the lytic cycle genes of the Epstein-Barr virus in the generation of lymphoblastoid cell line [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): Targeting the lytic cycle of the Epstein-Barr virus (EBV) has been considered a new treatment strategy for malignancies caused by this virus.
Mahboobeh Cheragh +3 more
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Protein Kinase CK2 and Epstein–Barr Virus
Biomedicines, 2023 Protein kinase CK2 is a pleiotropic protein kinase, which phosphorylates a number of cellular and viral proteins. Thereby, this kinase is implicated in the regulation of cellular signaling, controlling of cell proliferation, apoptosis, angiogenesis ...
Mathias Montenarh +2 more
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Differential methylation of the HPV 16 upstream regulatory region during epithelial differentiation and neoplastic transformation. [PDF]
PLoS ONE, 2011 High risk human papillomaviruses are squamous epitheliotropic viruses that may cause cervical and other cancers. HPV replication depends on squamous epithelial differentiation.
Svetlana Vinokurova +1 more
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Non-Coding RNA, 2022 Virus-encoded microRNAs (miRNAs) target viral and host mRNAs to repress protein production from viral and host genes, and regulate viral persistence, cell transformation, and evasion of the immune system.
Tetsuyuki Takahashi +4 more
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Viral Agents as Potential Drivers of Diffuse Large B-Cell Lymphoma Tumorigenesis
Viruses, 2022 Among numerous causative agents recognized as oncogenic drivers, 13% of total cancer cases occur as a result of viral infections. The intricacy and diversity of carcinogenic processes, however, raise significant concerns about the mechanistic function of
Esma Bilajac +6 more
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Scientific Reports, 2023 Infection with high-risk human papillomaviruses like HPV-16 and HPV-18 is highly associated with the development of cervical and other cancers. Malignant transformation requires viral oncoproteins E5, E6 and E7, which promote cell proliferation and ...
Jimena Hochmann +12 more
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Autophagy in Human T-Cell Leukemia Virus Type 1 (HTLV-1) Induced Leukemia
Frontiers in Oncology, 2021 Viruses play an important role in the development of certain human cancers. They are estimated to contribute 16% to all human cancers. Human T-cell leukemia virus type 1 (HTLV-1) was the first human retrovirus to be discovered and is the etiological ...
Nicolás Ducasa +10 more
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