Varicellovirus UL 49.5 proteins differentially affect the function of the transporter associated with antigen processing, TAP [PDF]
Cytotoxic T-lymphocytes play an important role in the protection against viral infections, which they detect through the recognition of virus-derived peptides, presented in the context of MHC class I molecules at the surface of the infected cell.
Wiertz, E.J.H.J. +80 more
core +2 more sources
Viral genome integration of canine papillomavirus 16
Papillomaviruses infect humans and animals, most often causing benign proliferations on skin or mucosal surfaces. Rarely, these infections persist and progress to cancer.
Jennifer Luff +5 more
doaj +1 more source
Unravelling the structure of viral replication complexes at super-resolution [PDF]
This work was supported by Biotechnology and Biomedical Sciences Research Council grant BB/H018719/1During infection, many RNA viruses produce characteristic inclusion bodies that contain both viral and host components.
Karl J. Oparka +12 more
core +1 more source
SPOC1-mediated antiviral host cell response is antagonized early in human adenovirus type 5 infection. [PDF]
Little is known about immediate phases after viral infection and how an incoming viral genome complex counteracts host cell defenses, before the start of viral gene expression.
Sabrina Schreiner +8 more
doaj +1 more source
Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection [PDF]
Deletion, anergy, and a spectrum of functional impairments can affect virus-specific CD8 cells in chronic viral infections. Here we characterize a low frequency population of CD8 cells present in chronic hepatitis B virus (HBV) infection which survive in
Ogg, GS +29 more
core +1 more source
Extensive studies of HTLV-1 and HTLV-2 over the last three decades have provided detailed knowledge on viral transformation, host-viral interactions and pathogenesis.
Rajaneesh eAnupam +2 more
doaj +1 more source
Overview on HTLV-I p12, p8, p30, p13: accomplices in persistent infection and viral pathogenesis.
The human T-lymphotropic virus type-1 (HTLV-1) is etiologically linked to adult T-cell leukemia/lymphoma (ATLL) and tropical spastic paraparesis/ HTLV-1 associated myelopathy (TSP/HAM).
Christophe eNicot, xue tao ebai
doaj +1 more source
In-vitro demonstration of cell-mediated immunity to vaccinia virus in man [PDF]
Cell mediated immunity to vaccinia virus in man was studied by lymphocyte transformation. Vaccinia antigen, propagated on BHK-21 and Vero cells, could be used successfully for in-vitro testing after partial purification as well as crude infectious ...
Koszinowski, Ulrich H. +2 more
core +1 more source
The role of coronin 1 during cell mediated immune responses [PDF]
Coronin 1 is one of 7 mammalian isoforms member of the evolutionary conserved WD40-repeat proteins that are involved in a variety of activities such a cell migration and cytokinesis.
Tchang, Vincent Sam Yong
core +1 more source
Herpesviral microRNAs in Cellular Metabolism and Immune Responses
The microRNAs (miRNAs) function as a key regulator in many biological processes through post-transcriptional suppression of messenger RNAs. Recent advancements have revealed that miRNAs are involved in many biological functions of cells.
Hyoji Kim +4 more
doaj +1 more source

