Liver Cell Transformation in Chronic HBV Infection
Viruses, 2009 Epidemiological studies have provided overwhelming evidence for a causal role of chronic HBV infection in the development of hepatocellular carcinoma (HCC), but the molecular mechanisms underlying virally-induced tumorigenesis remain largely debated.
Marie Annick Buendia +3 more
doaj +1 more source
EFFECT OF BOVINE VIRUS DIARRHOEA ON THE IMMUNE RESPONSE OF EGYPTIAN BUFFALO CALVES [PDF]
Veterinary Medical Journal - Giza, 1994 Five buffalo calves were experimentally infected with Singer strain of bovine viral diarrhea virus (BVDV). The hematological changes and immune response were investigated.
I REDA +7 more
doaj +1 more source
EFFECT OF BOVINE VIRUS DIARRHOEA ON THE IMMUNE RESPONSE OF EGYPTIAN BUFFALO CALVES [PDF]
Veterinary Medical Journal - Giza, 1992 Five buffalo calves were experimentally infected with Singer strain of bovine viral diarrhea virus (BVDV). The hematological changes and immune response were investigated.
A EL-SANOUSI +6 more
doaj +1 more source
Similarities and differences between the E5 oncoproteins of bovine papillomaviruses type 1 and type 4: Cytoskeleton, motility and invasiveness in E5-transformed bovine and mouse cells [PDF]
, 2006 Bovine papillomaviruses (BPVs) are oncogenic viruses. In cattle, BPV-1/2 is associated with urinary bladder cancer and BPV-4 with upper GI tract cancer. BPV E5 is a small hydrophobic protein localised in the endoplasmic reticulum (ER) and Golgi apparatus
Ullah, R. +13 more
core +1 more source
Viral DNA in Polyoma- and SV40-Transformed Cell Lines [PDF]
Proceedings of the National Academy of Sciences, 1968 It is clear that cells transformed by the small DNA-containing viruses, polyoma virus (Py) and SV40, harbor the viral DNA since they contain viral mRNA,1 and some lines even yield infectious virus after fusion with cells able to support the multiplication of the virus.2, 3 Very little is known, however, about the state of the viral DNA in these cells ...
H, Westphal, R, Dulbecco
openaire +2 more sources
Non-viral approaches to gene therapy [PDF]
, 1993 Several advances in non-viral gene transfer technology have been reported over the past year. Cationic lipids have been successfully used to deliver genes in vivo, providing a clear alternative to recombinant viruses.
Wagner, Ernst, Cotten, Matt
core +1 more source
Human Cytomegalovirus glycoprotein UL16 causes intracellular sequestration of NKG2D ligands, protecting against NK cell cytotoxicity. [PDF]
, 2003 The activating receptor, NKG2D, is expressed on a variety of immune effector cells and recognizes divergent families of major histocompatibility complex (MHC) class I-related ligands, including the MIC and ULBP proteins.
Sutherland, CL +13 more
core +1 more source
In vivo antagonistic role of the Human T-Cell Leukemia Virus Type 1 regulatory proteins Tax and HBZ.
PLoS Pathogens, 2021 Adult T cell leukemia (ATL) is an aggressive malignancy secondary to chronic infection by the human T-cell leukemia virus type 1 (HTLV-1) infection. Two viral proteins, Tax and HBZ, play central roles in ATL leukemogenesis.
Abdou Akkouche +6 more
doaj +1 more source
Immunodominance of lytic cycle antigens in Epstein-Barr virus-specific CD4+ T cell preparations for therapy. [PDF]
, 2007 Epstein-Barr virus (EBV) is associated with a number of human malignancies. EBV-positive post-transplant lymphoproliferative disease in solid organ and hematopoietic stem cell transplant recipients has been successfully treated by the adoptive transfer ...
Burdach, S. +36 more
core +1 more source
Epstein-Barr virus provides a new paradigm: a requirement for the immediate inhibition of apoptosis. [PDF]
PLoS Biology, 2005 DNA viruses such as herpesviruses are known to encode homologs of cellular antiapoptotic viral Bcl-2 proteins (vBcl-2s), which protect the virus from apoptosis in its host cell during virus synthesis.
Markus Altmann, Wolfgang Hammerschmidt
doaj +2 more sources