Results 101 to 110 of about 5,611,319 (281)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Simulation Research of Virtual Synchronous Machine Control System with Harmonic Suppression
Kongzhi Yu Xinxi Jishu, 2022 Virtual synchronous machine control strategy is an effective means to solve the problem of inertia lack in grid connection of new energy source, but oscillation link in control system makes harmonic content of the connection process of distributed power ...
CHENG Kun +4 more
doaj
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
AxiomsAccording to the World Health Organization (WHO), globally, cervical cancer ranks as the fourth most common cancer in women, with around 660,000 new cases in 2022.
Umar Shafique +4 more
doaj +1 more source
Distributed Cooperative Control of Multiple Vehicles Considering Communication Packets Losses
Kongzhi Yu Xinxi Jishu, 2022 Cooperative vehicle platoon control has great potential in relieving traffic congestion, improving driving safety and fuel economy, which is closely related to the progress of communication technology, especially the development of vehicle-to-vehicle ...
TAN Yan +6 more
doaj
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Hybrid Fuzzy Fractional for Multi-Phasic Epidemics: The Omicron–Malaria Case Study
Fractal and FractionalThis study introduces a novel Fuzzy Piecewise Fractional Derivative (FPFD) framework to enhance epidemiological modeling, specifically for the multi-phasic co-infection dynamics of Omicron and malaria.
Mohamed S. Algolam +6 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source