Results 101 to 110 of about 25,800,498 (305)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Simulation Research of Virtual Synchronous Machine Control System with Harmonic Suppression
Kongzhi Yu Xinxi Jishu, 2022 Virtual synchronous machine control strategy is an effective means to solve the problem of inertia lack in grid connection of new energy source, but oscillation link in control system makes harmonic content of the connection process of distributed power ...
CHENG Kun +4 more
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
AxiomsAccording to the World Health Organization (WHO), globally, cervical cancer ranks as the fourth most common cancer in women, with around 660,000 new cases in 2022.
Umar Shafique +4 more
doaj +1 more source
Distributed Cooperative Control of Multiple Vehicles Considering Communication Packets Losses
Kongzhi Yu Xinxi Jishu, 2022 Cooperative vehicle platoon control has great potential in relieving traffic congestion, improving driving safety and fuel economy, which is closely related to the progress of communication technology, especially the development of vehicle-to-vehicle ...
TAN Yan +6 more
doaj
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Comparison of three power system software packages for small-signal stability analysis [PDF]
, 2009 Includes bibliographical references (leaves 131-133).Many power system simulation tools exist for small-signal stability analysis. This is due to the rapid development of computer systems, higher industrial growth and the need for reliable power system ...
Mudau, Dovhani Selby
core +1 more source
Hybrid Fuzzy Fractional for Multi-Phasic Epidemics: The Omicron–Malaria Case Study
Fractal and FractionalThis study introduces a novel Fuzzy Piecewise Fractional Derivative (FPFD) framework to enhance epidemiological modeling, specifically for the multi-phasic co-infection dynamics of Omicron and malaria.
Mohamed S. Algolam +6 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source