Results 101 to 110 of about 2,331,184 (299)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

A Note on International Fiscal Policy Practices [PDF]

The paper proposes an overview of the literature in fiscal policies as well as a comparative assessment in an international context. A large section addresses the specific question of the European fiscal rule, namely the Stability and Growth Pact (SGP).
Thierry Warin
core  

Singapore: Financial System Stability Assessment

IMF Staff Country Reports, 2013
Singapore’s financial sector, which is dominated by the banking sector, remains robust despite a series of economic downturns and substantial asset price declines. Economic developments in the past few years have highlighted Singapore’s vulnerability to exogenous shocks, including the outbreak of Severe Acute Respiratory Syndrome (SARS).
openaire   +4 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Monetary Commitment, Institutional Constraints and Inflation: Empirical Evidence for OECD Countries since the 1970s [PDF]

Central bank independence (CBI) is a very important precondition for price stability. However, the empirical evidence for a correlation between both is relatively weak.
Andreas Freytag, Friedrich Schneider
core  

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Formulation and Evaluation of Radiance Serum Containing Astaxanthin–Zeaxanthin Nanoemulsions as an Anti-Wrinkle Agent: Stability, Ex Vivo, and In Vivo Assessments

Cosmetics
Reactive oxygen species (ROS), commonly known as free radicals, induced by UV radiation can compromise the dermal structure, leading to a loss of skin elasticity and subsequent wrinkle formation.
Lusi Nurdianti, Fajar Setiawan, Ira Maya, Taofik Rusdiana, Cahya Khairani Kusumawulan, Dolih Gozali, Dewi Peti Virgianti   +6 more
doaj   +1 more source

Evaluation of macroeconomic models for financial stability analysis [PDF]

As financial stability has gained focus in economic policymaking, the demand for analyses of financial stability and the consequences of economic policy has increased.
Dimitrios P. Tsomocos, Gunnar Bårdsen, Kjersti-Gro Lindquist   +2 more
core  

Belgium: Financial System Stability Assessment

IMF Staff Country Reports, 2013
This financial stability assessment provides an update on the significant regulatory and supervisory developments in the banking and insurance sectors of Belgium since 2006. The Belgian financial system is relatively large with solid capital buffers on aggregate, and the 2008 global financial crisis has had a major impact on the Belgian financial ...
openaire   +3 more sources